Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kaya Zhu"'
Autor:
Kyle R Cron, Kaya Zhu, Deepa S Kushwaha, Grace Hsieh, Dmitry Merzon, Jonathan Rameseder, Clark C Chen, Alan D D'Andrea, David Kozono
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73710 (2013)
Despite optimal radiation therapy (RT), chemotherapy and/or surgery, a majority of patients with locally advanced non-small cell lung cancer (NSCLC) fail treatment. To identify novel gene targets for improved tumor control, we performed whole genome
Externí odkaz:
https://doaj.org/article/5c1b9c99f508418da82f020479a25f2b
Autor:
Marina K Ayrapetov, Chang Xu, Yingli Sun, Kaya Zhu, Kalindi Parmar, Alan D D'Andrea, Brendan D Price
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26064 (2011)
Hypoxia inducible factor 1α (Hif1α) is a stress responsive transcription factor, which regulates the expression of genes required for adaption to hypoxia. Hif1α is normally hydroxylated by an oxygen-dependent prolylhydroxylase, leading to degradat
Externí odkaz:
https://doaj.org/article/a4ad1f0b9b1d4c9288621b5a0b7beeda
Autor:
Daniel T. Ruan, Francis D. Moore, Edward E. Whang, Kaya Zhu, Matthew A. Nehs, David Kozono, Chi-Iou Lin, Jacob Moalem, Nancy L. Cho
Publikováno v:
Surgery. 150:1032-1039
Necroptosis is a recently described mechanism of programmed cellular death. We hypothesize that necroptosis plays an important role in radiation-induced cell death in endocrine cancers.Thyroid and adrenocortical carcinoma cell lines were exposed to i
Autor:
Dmitry Merzon, Donald P. Pizzo, Hideyuki Saya, Olivier Harismendy, Scott R. VandenBerg, Ichiro Nakano, Valya Ramakrishnan, Hiroko Matsui, Masayuki Nitta, Deepa Kushwaha, Jie Li, Shan Zhu, Kaya Zhu, Chang-Hyuk Kwon, Clark C. Chen, Wei Hua, David D. Gonda, Oltea Sampetrean, Ying Mao, David Kozono
Publikováno v:
Proceedings of the National Academy of Sciences. 112
The available evidence suggests that the lethality of glioblastoma is driven by small subpopulations of cells that self-renew and exhibit tumorigenicity. It remains unclear whether tumorigenicity exists as a static property of a few cells or as a dyn
Autor:
Kyle R. Cron, Peter Deraska, Deepa Kushwaha, Alan D. D'Andrea, Colin O’Leary, Kaya Zhu, David Kozono
Background and Purpose: Radiotherapy (RT) is vital for the treatment of locally advanced non-small cell lung cancer (NSCLC), yet its delivery is limited by tolerances of adjacent organs. We sought therefore to identify and characterize gene targets w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081309b0b6c25b63852e407f2c50a62a
https://europepmc.org/articles/PMC4622494/
https://europepmc.org/articles/PMC4622494/
Autor:
Liat Stoler-Barak, Jerrold Weiss, Ofer Levy, Christine M. Barbon, Janice Russell, Alan D. D'Andrea, Robert J. Soiffer, Kaya Zhu, Jo-Anne Vergilio, Eva C. Guinan, Jeff Kutok, Geoffrey Cole, Leslie A. Kalish, Leighanne C. Gallington, Christine D. Palmer, Kalindi Parmar, Eugenie E. Suter, Annie R. Voskertchian, Christy J. Mancuso
Publikováno v:
Science translational medicine. 3(110)
Identification of safe, effective treatments to mitigate toxicity after extensive radiation exposure has proven challenging. Only a limited number of candidate approaches have emerged, and the U.S. Food and Drug Administration has yet to approve any
Autor:
Kalindi Parmar, Chang Xu, Brendan D. Price, Yingli Sun, Alan D. D'Andrea, Marina K. Ayrapetov, Kaya Zhu
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26064 (2011)
PLoS ONE
PLoS ONE
Hypoxia inducible factor 1α (Hif1α) is a stress responsive transcription factor, which regulates the expression of genes required for adaption to hypoxia. Hif1α is normally hydroxylated by an oxygen-dependent prolylhydroxylase, leading to degradat
Autor:
Abigail Hamilton, Jeffery L. Kutok, Koichi Akashi, Stephen M. Sykes, D. Gary Gilliland, Kalindi Parmar, Akiko Shimamura, Patricia Stuckert, Alan D. D'Andrea, Jung Min Kim, Mary Kathryn Deloach, Kaya Zhu
Fanconi anemia (FA) is a human genetic disease characterized by a DNA repair defect and progressive bone marrow failure. Central events in the FA pathway are the monoubiquitination of the Fancd2 protein and the removal of ubiquitin by the deubiquitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f206617739b6bf9027baaa0ac4436948
https://europepmc.org/articles/PMC2910804/
https://europepmc.org/articles/PMC2910804/
Autor:
Chang-Hyuk Kwon, Shan Zhu, Valya Ramakrishnan, Hideyuki Saya, Scott R. VandenBerg, Kaya Zhu, Wei Hua, David D. Gonda, Deepa Kushwaha, Oltea Sampetrean, Ichiro Nakano, Clark C. Chen, Masayuki Nitta, Hiroko Matsui, Donald P. Pizzo, Olivier Harismendy, Jie Li, Ying Mao, Dmitry Merzon, David Kozono
Publikováno v:
Neuro-Oncology. 17:v86.2-v86
Glioblastoma is one of the most devastating of human cancers, with near-uniform fatality within two years of diagnosis. Therapeutic failure is thought to be related to small subpopulation of cells that exhibit the properties of self-renewal and tumor
Autor:
Kaya Zhu, Valya Ramakrishnan, Donald P. Pizzo, Deepa Kushwaha, Clark C. Chen, Kimberly Ng, Webster K. Cavenee, Masayuki Nitta, Chang-Hyuk Kwon, Wei Hua, Olivier Harismendy, David D. Gonda, Oltea Sampetrean, Hideyuki Saya, Frank B. Furnari, Jie Li, Keith L. Ligon, Hiroko Matsui, Ying Mao, Dmitry Merzon, David Kozono, Shan Zhu, Scott R. VandenBerg, Bob S. Carter
Publikováno v:
Molecular Cancer Research. 13:PR02-PR02
Glioblastoma is one of the most devastating of human cancers, with near-uniform fatality within two years of diagnosis. Therapeutic failure is thought to be related to small subpopulation of cells that exhibit the properties of self-renewal and tumor