Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kay-Martin Johnsen"'
Autor:
Wei Meng, Christopher G. Fenton, Kay-Martin Johnsen, Hagar Taman, Jon Florholmen, Ruth H. Paulssen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract DNA methylation has been implied to play a role in the immune dysfunction associated with inflammatory bowel disease (IBD) and the disease development of ulcerative colitis (UC). Changes of the DNA methylation and correlated gene expression
Externí odkaz:
https://doaj.org/article/bc54cd138aab4111b45ebe330b96abf6
Publikováno v:
Frontiers in Gastroenterology, Vol 2 (2024)
BackgroundModerate to severe ulcerative colitis (UC) is generally treated with a step-up algorithm from 5-aminosalicylic acid (5-ASA) to biological agents. There is no general recommendation if or when to de-escalate or discontinue biological therapy
Externí odkaz:
https://doaj.org/article/e4b73ea1ffe244e1bc70aaa0e8a0109c
Autor:
Rasmus Goll, Øystein K. Moe, Kay-Martin Johnsen, Renate Meyer, Joachim Friestad, Mona D. Gundersen, Hege Kileng, Knut Johnsen, Jon R. Florholmen
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background and aims Biological therapy for inflammatory bowel disease is efficient in many cases but not all. The underlying molecular mechanisms behind non-response to biological therapy in inflammatory bowel disease are poorly described. T
Externí odkaz:
https://doaj.org/article/24585aa8af0c4f278536725289b66640
Autor:
Kay-Martin Johnsen, Jon Florholmen, Øystein K. Moe, Mona Gundersen, Julia Beilfuss, Hege Kileng, Sveinung W. Sørbye, Rasmus Goll
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background The long-term outcomes of Ulcerative colitis (UC) after discontinuation of biological therapy are largely unknown. There is also a lack of accurate and validated markers that can predict outcome after withdrawal accurately. The ai
Externí odkaz:
https://doaj.org/article/da78846b309b46bb9fe878e44427527f
Autor:
Jon R. Florholmen, Kay-Martin Johnsen, Renate Meyer, Trine Olsen, Øystein K. Moe, Petter Tandberg, Mona D. Gundersen, Jan-Magnus Kvamme, Knut Johnsen, Terje Løitegård, Gabriele Raschpichler, Cecilia Vold, Sveinung W. Sørbye, Rasmus Goll
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background There are no accurate markers that can predict clinical outcome in ulcerative colitis at time of diagnosis. The aim of this study was to explore a comprehensive data set to identify and validate predictors of clinical outcome in t
Externí odkaz:
https://doaj.org/article/9177c6b0487643b7b2d2feb0352a80cd
Autor:
Oddmund Nestegard, Behrouz Moayeri, Fred-Arne Halvorsen, Tor Tønnesen, Sveinung Wergeland Sørbye, Eyvind Paulssen, Kay-Martin Johnsen, Rasmus Goll, Jon Ragnar Florholmen, Kjetil K. Melby
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Background Increasing prevalence of antibiotic resistance especially to clarithromycin and metronidazole has been observed in Helicobacter pylori (H. pylori). Aim To characterize the antimicrobial resistance pattern of H. pylori before and after trea
Externí odkaz:
https://doaj.org/article/f9106bca6b4b4323a3d35e3061a30945
Autor:
Oddmund Nestegard, Kay-Martin Johnsen, Sveinung W Sørbye, Fred-Arne Halvorsen, Tor Tønnessen, Eyvind J Paulssen, Kjetil K Melby, Rasmus Goll, Jon Florholmen
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238944 (2020)
Background and aimsPatients that have failed therapy for Helicobacter pylori (H. pylori) infection are incompletely characterized. The aim of this study was to characterize a H. pylori treatment resistant cohort compared to the cohorts of newly diagn
Externí odkaz:
https://doaj.org/article/f1efa49d151243efba30d24ab2327013
Publikováno v:
Functional & Integrative Genomics. 23
Due to the lack of clinical, immunologic, genetic, and laboratory markers to predict remission in ulcerative colitis (UC) without relapse, there is no clear recommendation regarding withdrawal of therapy. Therefore, this study was to investigate if t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c16bf24ead8d6896aa558109dedbe082
https://doi.org/10.1007/s10142-023-01099-9
https://doi.org/10.1007/s10142-023-01099-9
Autor:
Mona Dixon Gundersen, Kenneth Bowitz Larsen, Kay Martin Johnsen, Rasmus Goll, Jon Florholmen, Guttorm Haraldsen
Epithelial alarmins are gaining interest as therapeutic targets for chronic inflammation. The nuclear alarmin interleukin-33 (IL-33) is upregulated in the colonic mucosa of acute ulcerative colitis (UC) and may represent an early instigator of the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017c3d8c94536639d9d4398ec8443e13
https://hdl.handle.net/10037/27414
https://hdl.handle.net/10037/27414
Autor:
Terje Løitegård, Jon Florholmen, Jan-Magnus Kvamme, Øystein Kittel Moe, Trine Olsen, Rasmus Goll, Cecilia Vold, Kay-Martin Johnsen, Mona Dixon Gundersen, Petter Tandberg, Gabriele Raschpichler, Knut Johnsen, Sveinung Wergeland Sørbye, Renate Meyer
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Gastroenterology
BMC Gastroenterology
Background There are no accurate markers that can predict clinical outcome in ulcerative colitis at time of diagnosis. The aim of this study was to explore a comprehensive data set to identify and validate predictors of clinical outcome in the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc33be21f597ac47913d3b06fd8a0588
https://doi.org/10.1186/s12876-020-01447-0
https://doi.org/10.1186/s12876-020-01447-0