Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kay Schreiter"'
Autor:
Grit Zahn, Diana M. Willmes, Nermeen N. El-Agroudy, Christopher Yarnold, Richard Jarjes-Pike, Sabine Schaertl, Kay Schreiter, Wiebke Gehrmann, Andrea Kuan Cie Wong, Tommaso Zordan, Jörg König, Jens Jordan, Andreas L. Birkenfeld
Publikováno v:
Metabolites, Vol 12, Iss 8, p 732 (2022)
Mammalian INDY (mINDY, NaCT, gene symbol SLC13A5) is a potential target for the treatment of metabolically associated fatty liver disease (MAFLD). This study evaluated the effects of a selective, cross-species active, non-competitive, non-substrate-l
Externí odkaz:
https://doaj.org/article/df864a926cf9414baf12212f6718bd61
Publikováno v:
Xenobiotica. 47:538-546
1. The pharmacokinetics and metabolism of lumiracoxib in male C57bl/6J mice were investigated following a single oral dose of 10 mg/kg. 2. Lumiracoxib achieved peak observed concentrations in the blood of 1.26 + 0.51 μg/mL 0.5 h (0.5–1.0) post-dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06712fafe93ae7eafcdcbb2ddc462fc1
https://doi.org/10.1080/00498254.2016.1206239
https://doi.org/10.1080/00498254.2016.1206239
Autor:
Lisbeth N Fink, Christina Schmidt, Søren L. Pedersen, Viggo B. Kristiansen, Nicolai Rhee, Kristin Breitschopf, Erik Wandall, Tina Vilsbøll, Matthias Schäfer, Chen Zhang, Tina Jorsal, Steffen U. Friis, Katrine Fabricius, Kay Schreiter, Ebbe Langholz, Thomas Hübschle, Filip K. Knop, Henrik H. Hansen, Maria Luisa Fernandez-Cachon, Jacob Jelsing, Peter Vilmann, Philip J. Larsen, Thorsten Schmidt, Kristoffer T. G. Rigbolt, Lisbeth Elster, Stefan Theis
Publikováno v:
Peptides. 101
Aim To determine whether intestinal expression of guanylate cyclase activator 2A (GUCA2A) and guanylate cyclase activator 2B (GUCA2B) genes is regulated in obese humans following Roux-en-Y gastric bypass (RYGB), and to evaluate the corresponding guan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6274d402d5a89d4ea987ac6f35e72a50
https://pubmed.ncbi.nlm.nih.gov/29289697
https://pubmed.ncbi.nlm.nih.gov/29289697
Autor:
Michael Feigh, Joseph Grimsby, Pernille Barkholt, Matthias Austen, John Le Lay, Terrence O'Day, Lutz Jermutus, Chester Bittencourt Sacramento, David M. Smith, Christina Reers, Stephanie Oldham, Maria Sörhede Winzell, James L. Trevaskis, Christopher J. Rhodes, Victor G. Howard, Brandon B. Boland, Jennifer Cann, Nicholas Bhagroo, Cord Dohrmann, Yuan Chang, Safina Ali, Cristina M. Rondinone, Uwe Andag, Kay Schreiter, Arun Sharma, Hani A. Jouihan, Matthew P. Coghlan, Simon Thompson
Publikováno v:
Diabetes. 66(7)
Neurturin (NRTN), a member of the glial-derived neurotrophic factor family, was identified from an embryonic chicken pancreatic cDNA library in a screen for secreted factors. In this study, we assessed the potential antidiabetic activities of NRTN re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22df68faf7c73de1a63baaf903cf58d6
https://pubmed.ncbi.nlm.nih.gov/28408435
https://pubmed.ncbi.nlm.nih.gov/28408435
Autor:
Markus Zweckstetter, Herbert Jäckle, Catharina Netter, Markus C. Wahl, Min-Kyu Cho, Kay Schreiter, Babette Aicher, Stefan Jäkel, Ralf Jauch
Publikováno v:
The EMBO Journal. 25:4020-4032
Autoinhibition is a recurring mode of protein kinase regulation and can be based on diverse molecular mechanisms. Here, we show by crystal structure analysis, nuclear magnetic resonance (NMR)-based nucleotide affinity studies and rational mutagenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec04efee2958f3e9133a3d64ade8fd72
https://doi.org/10.1038/sj.emboj.7601285
https://doi.org/10.1038/sj.emboj.7601285
Autor:
Herbert Jäckle, Babette Aicher, Catharina Netter, Stefan Jäkel, Kay Schreiter, Ralf Jauch, Markus C. Wahl
Publikováno v:
Structure. 13(10):1559-1568
Human mitogen-activated protein kinases (MAPK)-interacting kinases 1 and 2 (Mnk1 and Mnk2) target the translational machinery by phosphorylation of the eukaryotic initiation factor 4E (eIF4E). Here, we present the 2.1 A crystal structure of a nonphos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45d082e66b054b89f9e10d0e7d621d8
Autor:
Renate Renkawitz-Pohl, Leonie U. Hempel, Nicole Blümer, Ansgar Santel, Martin Hollmann, Mireille A. Schäfer, Kay Schreiter
Publikováno v:
Mechanisms of development. 110(1-2)
The Drosophila don juan (dj) gene encodes a basic protein that is expressed solely in the male germline and shows structural similarities to the linker histone H1. Don Juan is located in two different subcellular structures: in the nucleus during the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21b63de361f3304874be7e77fc17998
https://pubmed.ncbi.nlm.nih.gov/11744372
https://pubmed.ncbi.nlm.nih.gov/11744372