Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kay O. Schink"'
Publikováno v:
Molecular & Cellular Oncology, Vol 6, Iss 6 (2019)
Secretion of matrix metalloproteinases (MMPs) enables cancer cells to degrade extracellular matrix, thus promoting tumor invasion and metastasis. We have recently found that the endosomal protein WDFY2 serves as a gatekeeper for MMP recycling from en
Externí odkaz:
https://doaj.org/article/e629ecaef6414a519d3b161d7da5a6e3
Autor:
Kari-Anne M. Frikstad, Elisa Molinari, Marianne Thoresen, Simon A. Ramsbottom, Frances Hughes, Stef J.F. Letteboer, Sania Gilani, Kay O. Schink, Trond Stokke, Stefan Geimer, Lotte B. Pedersen, Rachel H. Giles, Anna Akhmanova, Ronald Roepman, John A. Sayer, Sebastian Patzke
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1907-1922.e6 (2019)
Summary: CEP104 is an evolutionarily conserved centrosomal and ciliary tip protein. CEP104 loss-of-function mutations are reported in patients with Joubert syndrome, but their function in the etiology of ciliopathies is poorly understood. Here, we sh
Externí odkaz:
https://doaj.org/article/64cd3655c3764130ba8e0811b1fe5fe9
Autor:
Johan Sternemalm, Stefan Geimer, Kari-Anne M Frikstad, Kay O Schink, Trond Stokke, Sebastian Patzke
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 8, p e0134789 (2015)
PLoS ONE, Vol 10, Iss 8, p e0134789 (2015)
Deleterious mutations of the Centrosome/Spindle Pole associated Protein 1 gene, CSPP1, are causative for Joubert-syndrome and Joubert-related developmental disorders. These disorders are defined by a characteristic mal-development of the brain, but f
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 35(10)
Phosphatidylinositol 3-phosphate (PtdIns3P) is generated on the cytosolic leaflet of cellular membranes, primarily by phosphorylation of phosphatidylinositol by class II and class III phosphatidylinositol 3-kinases. The bulk of this lipid is found on
Autor:
Alina C Stiebler, Johannes Freitag, Kay O Schink, Thorsten Stehlik, Britta A M Tillmann, Julia Ast, Michael Bölker
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004685 (2014)
Translation of mRNA into a polypeptide chain is a highly accurate process. Many prokaryotic and eukaryotic viruses, however, use leaky termination of translation to optimize their coding capacity. Although growing evidence indicates the occurrence of
Externí odkaz:
https://doaj.org/article/49e739a892c34350bb49356d76d0aac6
Autor:
Clara L Oeste, Mario Pinar, Kay O Schink, Javier Martínez-Turrión, Harald Stenmark, Miguel A Peñalva, Dolores Pérez-Sala
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107190 (2014)
The C-terminal ends of small GTPases contain hypervariable sequences which may be posttranslationally modified by defined lipid moieties. The diverse structural motifs generated direct proteins towards specific cellular membranes or organelles. Howev
Externí odkaz:
https://doaj.org/article/7b33b3aa711644969a46dd3d54e503ad