Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Kay Nolte"'
Autor:
Celine Chiu, Alma Küchler, Christel Depienne, Corinna Preuße, Adela Della Marina, Andre Reis, Frank J. Kaiser, Kay Nolte, Andreas Hentschel, Ulrike Schara-Schmidt, Heike Kölbel, Andreas Roos
Publikováno v:
Skeletal Muscle, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Background TCF4 acts as a transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5 motif. Dominant variants in TCF4 are associated with the manifestation of Pitt-Hopkins syndrome, a rare disease characterized by severe mental
Externí odkaz:
https://doaj.org/article/2e484f64d83a4c958c3c49c8b122eed4
Autor:
Jingjin Liu, Michael Veldeman, Anke Höllig, Kay Nolte, Lisa Liebenstund, Antje Willuweit, Karl-Josef Langen, Rolf Rossaint, Mark Coburn
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract In a previous study from our group, argon has shown to significantly attenuate brain injury, reduce brain inflammation and enhance M2 microglia/macrophage polarization until 7 days after ischemic stroke. However, the long-term effects of arg
Externí odkaz:
https://doaj.org/article/8eafe687fe8f415fa7a21f588f4b672a
Autor:
Jingjin Liu, Kay Nolte, Gary Brook, Lisa Liebenstund, Agnieszka Weinandy, Anke Höllig, Michael Veldeman, Antje Willuweit, Karl-Josef Langen, Rolf Rossaint, Mark Coburn
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-13 (2019)
Abstract Background In recent years, argon has been shown to exert neuroprotective effects in an array of models. However, the mechanisms by which argon exerts its neuroprotective characteristics remain unclear. Accumulating evidence imply that argon
Externí odkaz:
https://doaj.org/article/5856d56a38d142378c1ae3d8da066bf3
Autor:
Anne Brücken, Christian Bleilevens, Philipp Berger, Kay Nolte, Nadine T. Gaisa, Rolf Rossaint, Gernot Marx, Matthias Derwall, Michael Fries
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Guidelines endorse targeted temperature management to reduce neurological sequelae and mortality after cardiac arrest (CA). Additional therapeutic approaches are lacking. Inhaled nitric oxide (iNO) given post systemic ischemia/reperfusion in
Externí odkaz:
https://doaj.org/article/133d2956de0f4dc6af449015ff033bd7
Autor:
Miriam Christina Heinen, Anne Babler, Joachim Weis, Johannes Elsas, Kay Nolte, Markus Kipp, Willi Jahnen-Dechent, Martin Häusler
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206597 (2018)
BACKGROUND:The liver-derived plasma protein fetuin-A is strongly expressed during fetal life, hence its name. Fetuin-A protein is normally present in most fetal organs and tissues, including brain tissue. Fetuin-A was neuroprotective in animal models
Externí odkaz:
https://doaj.org/article/b351d3ab60394cf2880eedb8389fa803
Autor:
Michael Veldeman, Mark Coburn, Rolf Rossaint, Hans Clusmann, Kay Nolte, Benedikt Kremer, Anke Höllig
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
ObjectiveThe neuroprotective properties of the noble gas xenon have already been demonstrated using a variety of injury models. Here, we examine for the first time xenon’s possible effect in attenuating early brain injury (EBI) and its influence on
Externí odkaz:
https://doaj.org/article/3c38753410c5472980c7a6508eb68b10
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123398 (2015)
Recently aside from the "classic" endovascular monofilament perforation technique to induce experimental subarachnoid hemorrhage (SAH) a modification using a tungsten wire advanced through a guide tube has been described. We aim to assess both techni
Externí odkaz:
https://doaj.org/article/bef515674b1d4232a315771d3c07fdbf
Autor:
Agnieszka Weinandy, Marc D. Piroth, Anand Goswami, Kay Nolte, Bernd Sellhaus, Jose Gerardo-Nava, Michael Eble, Stefan Weinandy, Christian Cornelissen, Hans Clusmann, Bernhard Lüscher, Joachim Weis
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 3, Pp 207-220.e4 (2014)
Overexpression of the epidermal growth factor receptor (EGFR) is observed in a large number of neoplasms. The monoclonal antibody cetuximab/Erbitux is frequently applied to treat EGFR-expressing tumors. However, the application of cetuximab alone or
Externí odkaz:
https://doaj.org/article/681e81e275144f8a84ccf59996f54d45
Autor:
Martin Hasselblatt, Christian Thomas, Aniello Federico, Karolina Nemes, Pascal D. Johann, Brigitte Bison, Susanne Bens, Sonja Dahlum, Uwe Kordes, Antje Redlich, Lienhard Lessel, Kristian W. Pajtler, Christian Mawrin, Ulrich Schüller, Kay Nolte, Christof M. Kramm, Felix Hinz, Felix Sahm, Caterina Giannini, Judith Penkert, Christian P. Kratz, Stefan M. Pfister, Reiner Siebert, Werner Paulus, Marcel Kool, Michael C. Frühwald
Atypical teratoid/rhabdoid tumor (AT/RT) is a malignant central nervous system tumor predominantly affecting infants. Mutations of SMARCB1 or (rarely) SMARCA4 causing loss of nuclear SMARCB1 or SMARCA4 protein expression are characteristic features,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea3e29193baaa69a9da863682580409
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/95197
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/95197
Autor:
Matthias Begemann, Steffen Koschmieder, Inger Johanne Thuestad, Mats Geijer, Christopher Lindberg, Kay Nolte, Elizabeth J. Luna, Anders Oldfors, Burkhard Gess, Yassir Abdul Rahim, Miriam Elbracht, Michael Gramlich, Lea Hitpass, Cordula Knopp, Hanns Lochmüller, Carola Hedberg-Oldfors, Robert Meyer, Kittichate Visuttijai, Eva Lausberg, Florian Kraft, Rebekka Götzl, Joachim Weis, Ingo Kurth, Kristjan Karason
Publikováno v:
Brain
Hedberg-Oldfors et al. report that mutations in supervillin cause a novel structural myopathy with prominent lobulated type 1 fibres, myofibrillar disintegration and signs of altered proteostasis and impaired autophagy. Clinical signs include anomali