Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kay M. Crissman"'
Autor:
Kay M. Crissman, David B. Peden, Neil E. Alexis, Michelle L. Hernandez, Haibo Zhou, Carole Robinette, Bingqing Zhou, Gary E. Hatch
Publikováno v:
Inhalation Toxicology. 21:173-181
Oxidative stress plays a significant role in allergic airway inflammation. Supplementation with alpha-tocopherol (alone or combined with ascorbate/vitamin C) has been assessed as an intervention for allergic airway diseases with conflicting results.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a62153d03e4da0829b56ec8ccf47c9
https://doi.org/10.1080/08958370802161077
https://doi.org/10.1080/08958370802161077
Autor:
Lisa A. Dailey, Elizabeth D. Hilborn, Robert F. Foronjy, Andrew J. Ghio, Dale Uyeminami, Judy H. Richards, Jacqueline G. Stonehuerner, Kay M. Crissman, Jacqueline D. Carter, Kent E. Pinkerton
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 178:1130-1138
Lung injury after cigarette smoking is related to particle retention. Iron accumulates with the deposition of these particles.We tested the postulate that (1) injury after smoking correlates with exposure to the particulate fraction of cigarette smok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbfab13ed3332cf9998aa319a04e0af
https://doi.org/10.1164/rccm.200802-334oc
https://doi.org/10.1164/rccm.200802-334oc
Autor:
J. E. Schmid, Gary E. Hatch, Kay M. Crissman, Allen D. Ledbetter, William O. Ward, Judy E. Richards, Urmila P. Kodavanti, Mette C. Schladweiler
Publikováno v:
Inhalation toxicology. 27
We examined the hypothesis that antioxidant substances and enzymes in lung, heart and in bronchoalveolar lavage fluid (BALF) are altered in response to O3 in cardiovascular disease and/or metabolic syndrome (CVD)-prone rat models. CVD strains [sponta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd3078c78b877c59f824575b635d98e
https://pubmed.ncbi.nlm.nih.gov/26667331
https://pubmed.ncbi.nlm.nih.gov/26667331
Autor:
Eva Nozik-Grayck, Andrew T. McKie, Xinchao Wang, Andrew J. Ghio, Claude A. Piantadosi, Lisa B. Mamo, Kay M. Crissman, Jennifer L. Turi
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 291:L272-L280
Catalytically active iron in the lung causes oxidative stress and promotes microbial growth that can be limited by intracellular sequestration of iron within ferritin. Because cellular iron uptake requires membrane ferrireductase activity that in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7197a4e330820047aa9cc7bc9fb01f4a
https://doi.org/10.1152/ajplung.00342.2005
https://doi.org/10.1152/ajplung.00342.2005
Autor:
John K. McGee, Peter S. Gilmour, Urmila P. Kodavanti, Jerry Highfill, Kent E. Pinkerton, David Davies, Judy H. Richards, Daniel L. Costa, Debora L. Andrews, Kay M. Crissman, Leon Walsh, Mette C. Schladweiler, Allen D. Ledbetter
Publikováno v:
Environmental Health Perspectives
Several studies have reported health effects of concentrated ambient particles (CAP) in rodents and humans; however, toxicity end points in rodents have provided inconsistent results. In 2000 we conducted six 1-day exposure studies where spontaneousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e600961304575cad0844b0816e86caad
https://doi.org/10.1289/ehp.7868
https://doi.org/10.1289/ehp.7868
Autor:
J. J. L. Sienra-Monge, Hortensia Moreno-Macías, Kay M. Crissman, M X Ruiz-Navarro, Norma Isabel Reyes-Ruiz, Gary E. Hatch, Isabelle Romieu, Matiana Ramirez-Aguilar, B. E. del Rio-Navarro, Ralph Slade, Robert B. Devlin
Publikováno v:
Clinical and Experimental Immunology. 138:317-322
SUMMARY The inflammatory response to ozone in atopic asthma suggests that soluble mediators of inflammation are released in response to oxidant stress. Antioxidants may alleviate additional oxidative stress associated with photochemical oxidant pollu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26cdd9b3e80a79cd5092ba30682c8c11
https://doi.org/10.1111/j.1365-2249.2004.02606.x
https://doi.org/10.1111/j.1365-2249.2004.02606.x
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 281:L807-L815
Epidemiology studies show association of morbidity and mortality with exposure to ambient air particulate matter (PM). Metals present in PM may catalyze oxidation of important lipids and proteins present in the lining of the respiratory tract. The pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30edf0d941a9b154616a5d5de9a74e25
https://doi.org/10.1152/ajplung.2001.281.4.l807
https://doi.org/10.1152/ajplung.2001.281.4.l807
Publikováno v:
Toxicology and Industrial Health. 17:285-293
The present study compares acute and subchronic episodic exposures to phosgene to test the applicability of the `concentration×time’ ( C×T) product as a measure of exposure dose, and to relate acute toxicity and adaptive responses to chronic toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0731bf5e5172dcf77a6be55164bd28
https://doi.org/10.1191/0748233701th123oa
https://doi.org/10.1191/0748233701th123oa
Publikováno v:
Chest. 118:814-823
Study objectives: The extravasation of erythrocytes into the human lung occurs in a myriad of pulmonary disorders. Metal that is initially included in hemoglobin has been postulated to precipitate a disequilibrium in iron metabolism, to present an ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d6d8934678202c7907f38140bd21ea
https://doi.org/10.1378/chest.118.3.814
https://doi.org/10.1378/chest.118.3.814
Autor:
Heather H. Bobb, Judy H. Richards, Kay M. Crissman, Jacqueline D. Carter, Funmei Yang, Andrew J. Ghio
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 278:L1051-L1061
Using the hypotransferrinemic (Hp) mouse model, we studied the effect of altered iron homeostasis on the defense of the lung against a catalytically active metal. The homozygotic ( hpx/ hpx) Hp mice had greatly diminished concentrations of both serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d120ab0ca67bf19af5907708585a3c
https://doi.org/10.1152/ajplung.2000.278.5.l1051
https://doi.org/10.1152/ajplung.2000.278.5.l1051