Evidence of Extended Thermo-Stability of Typhoid Polysaccharide Conjugate Vaccines

Autor: Fang Gao, Kay Lockyer, Alastair Logan, Sarah Davis, Barbara Bolgiano, Sjoerd Rijpkema, Gopal Singh, Sai D. Prasad, Samuel Pradeep Dondapati, Gurbaksh Singh Sounkhla

Publikováno v: Microorganisms, Vol 9, Iss 8, p 1707 (2021)

Typhoid conjugate vaccines (TCV) are effective in preventing enteric fever caused by Salmonella enterica serovar Typhi in Southeast Asia and Africa. To facilitate vaccination with the Vi capsular polysaccharide–tetanus toxoid conjugate vaccine, Typ

Externí odkaz: https://doaj.org/article/381c9022afef4323a74babf715a1a9eb

Evidence of Extended Thermo-Stability of Typhoid Polysaccharide Conjugate Vaccines

Autor: Barbara Bolgiano, Alastair Logan, Kay Lockyer, Gopal Singh, Gurbaksh Singh Sounkhla, Samuel Pradeep Dondapati, Sai D Prasad, Sjoerd Rijpkema, Sarah Davis, Fang Gao

Publikováno v: Microorganisms
Volume 9
Issue 8
Microorganisms, Vol 9, Iss 1707, p 1707 (2021)

Typhoid conjugate vaccines (TCV) are effective in preventing enteric fever caused by Salmonella enterica serovar Typhi in Southeast Asia and Africa. To facilitate vaccination with the Vi capsular polysaccharide–tetanus toxoid conjugate vaccine, Typ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845560047731e4226ef428685fcb8d1c

Higher mass meningococcal group C-tetanus toxoid vaccines conjugated with carbodiimide correlate with greater immunogenicity

Autor: Fang Gao, Barbara Bolgiano, Robert J. Francis, Bhagwati Khatri, Jeremy P. Derrick, Richard Stebbings, Kay Lockyer, David Eastwood

Publikováno v: Derrick, J & et al. 2020, ' Higher mass meningococcal group C-tetanus toxoid vaccines conjugated with carbodiimide correlate with greater immunogenicity ', Vaccine, vol. 38, no. 13 . https://doi.org/10.1016/j.vaccine.2020.02.012

To examine the link between meningococcal C (MenC) vaccine size and immunogenic response, a panel of MenC glycoconjugate vaccines were prepared differing in chain length, molar mass and hydrodynamic volume. The preparations consisted of different len

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0ee881d12badf9d336f0909fb20dd5
https://pubmed.ncbi.nlm.nih.gov/32089463

Evaluation of two WHO First International Standards for Vi polysaccharide from Citrobacter freundii and Salmonella enterica subspecies enterica serovar Typhi

Autor: Kay Lockyer, Carolyn Swann, Alastair Logan, Peter Rigsby, Barbara Bolgiano, Sjoerd Rijpkema, Fang Gao

Publikováno v: Biologicals : journal of the International Association of Biological Standardization. 57

Numerous Vi capsular polysaccharide (Vi PS) conjugate vaccines to protect young children and infants from Typhoid are either licensed or under development. These vaccines are evaluated by laboratory methods to ensure their potency and that quality re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25d7af3627baa5f8ecc8f961059aa71
https://pubmed.ncbi.nlm.nih.gov/30502020

A physico-chemical assessment of the thermal stability of pneumococcal conjugate vaccine components

Autor: Fang Gao, Barbara Bolgiano, Karena Burkin, Kay Lockyer, Dennis T. Crane

Publikováno v: Human Vaccines & Immunotherapeutics

Physico-chemical analysis of pneumococcal polysaccharide (PS)-protein conjugate vaccine components used for two commercially licensed vaccines was performed to compare the serotype- and carrier protein-specific stabilities of these vaccines. Nineteen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4a7c17a7ff86dc5e176dcc5c5530a7
http://europepmc.org/articles/PMC4977451