Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Kay L. Double"'
Publikováno v:
Research Integrity and Peer Review, Vol 8, Iss 1, Pp 1-7 (2023)
Abstract Background This study aimed to investigate how strongly Australian university codes of research conduct endorse responsible research practices. Methods Codes of research conduct from 25 Australian universities active in health and medical re
Externí odkaz:
https://doaj.org/article/96ff9f1c110c426b9725ea23796beaed
Autor:
Benjamin G. Trist, Jennifer A. Fifita, Alison Hogan, Natalie Grima, Bradley Smith, Claire Troakes, Caroline Vance, Christopher Shaw, Safa Al-Sarraj, Ian P. Blair, Kay L. Double
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Multiple neurotoxic proteinopathies co-exist within vulnerable neuronal populations in all major neurodegenerative diseases. Interactions between these pathologies may modulate disease progression, suggesting they may constitute targets for
Externí odkaz:
https://doaj.org/article/6009cd789000488891a5da5a25f5909a
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract The Bradford Hill model evaluates the causal inference of one variable on another by assessing whether evidence of the suspected causal variable aligns with a set of nine criteria proposed by Bradford Hill, each representing fundamental tene
Externí odkaz:
https://doaj.org/article/5bcfbed266bc4ea58c4afce7e0cd8331
Autor:
Louis C. Penning, Marina Berenguer, Anna Czlonkowska, Kay L. Double, Petr Dusek, Carmen Espinós, Svetlana Lutsenko, Valentina Medici, Wiebke Papenthin, Wolfgang Stremmel, Jose Willemse, Ralf Weiskirchen
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 420 (2023)
Wilson disease (WD) is a rare, inherited metabolic disorder manifested with varying clinical presentations including hepatic, neurological, psychiatric, and ophthalmological features, often in combination. Causative mutations in the ATP7B gene result
Externí odkaz:
https://doaj.org/article/acc995f2df7b45f3959c8fccf8a57327
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247920 (2021)
BackgroundTranscranial sonography is increasingly used to aid clinical diagnoses of movement disorders, for example, to identify an enlarged area of substantia nigra echogenicity in patients with Parkinson's disease.ObjectiveThe current study investi
Externí odkaz:
https://doaj.org/article/5cc1aa3ea5174b86bb1d2c6cafd75a80
Autor:
Gabrielle Todd, Caroline D. Rae, Janet L. Taylor, Nigel C. Rogasch, Jane E. Butler, Michael Hayes, Robert A. Wilcox, Simon C. Gandevia, Karl Aoun, Adrian Esterman, Simon J. G. Lewis, Julie M. Hall, Elie Matar, Jana Godau, Daniela Berg, Christian Plewnia, Anna‐Katharina von Thaler, Clarence Chiang, Kay L. Double
Publikováno v:
Journal of Neuroscience Research. 101:263-277
Substantia nigra (SN) hyperechogenicity, viewed with transcranial ultrasound, is a risk marker for Parkinson's disease. We hypothesized that SN hyperechogenicity in healthy adults aged 50–70 years is associated with reduced short-interval intracort
Autor:
Jacqueline Shehadeh, Kay L. Double, Karen E. Murphy, Larisa Bobrovskaya, Stefanie Reyes, Peter R. Dunkley, Glenda M. Halliday, Phillip W. Dickson
Publikováno v:
Neurobiology of Disease, Vol 130, Iss , Pp 104524- (2019)
Tyrosine hydroxylase is the key enzyme controlling the synthesis of the catecholamines including dopamine. The breakdown of dopamine into toxic compounds has been suggested to have a key role in the degeneration of the dopaminergic neurons in Parkins
Externí odkaz:
https://doaj.org/article/9c2ed183cbfe49b9b4a0b1484f716687
Autor:
Dominic J Hare, Bárbara Rita Cardoso, Erika P Raven, Kay L Double, David I Finkelstein, Ewa A Szymlek-Gay, Beverley-Ann Biggs
Publikováno v:
npj Parkinson's Disease, Vol 3, Iss 1, Pp 1-5 (2017)
Abstract Iron accumulates gradually in the ageing brain. In Parkinson’s disease, iron deposition within the substantia nigra is further increased, contributing to a heightened pro-oxidant environment in dopaminergic neurons. We hypothesise that ind
Externí odkaz:
https://doaj.org/article/f22c5328fdf74dc0b1ae3c8bb9fca3a3
Autor:
Glenda M. Halliday, Benjamin G. Trist, Asuncion Carmona, Gerald Falkenberg, Stéphane Roudeau, Richard Ortega, Stéphane Claverol, Stijn Van Malderen, Katherine M. Davies, Yann Rufin, Kay L. Double
Publikováno v:
Analytical Chemistry
Analytical Chemistry, American Chemical Society, 2021, 93 (32), pp.11108-11115. ⟨10.1021/acs.analchem.1c01128⟩
Analytical chemistry 93(32), 11108-11115 (2021). doi:10.1021/acs.analchem.1c01128
Analytical Chemistry, American Chemical Society, 2021, 93 (32), pp.11108-11115. ⟨10.1021/acs.analchem.1c01128⟩
Analytical chemistry 93(32), 11108-11115 (2021). doi:10.1021/acs.analchem.1c01128
Analytical chemistry 93(32), 11108 - 11115 (2021). doi:10.1021/acs.analchem.1c01128
Studies of the metal content of metalloproteins in tissues from the human central nervous system (CNS) can be compromised by preparative techniques which alter l
Studies of the metal content of metalloproteins in tissues from the human central nervous system (CNS) can be compromised by preparative techniques which alter l
Iron has a long and storied history in Parkinson disease and related disorders. This essential micronutrient is critical for normal brain function, but abnormal brain iron accumulation has been associated with extrapyramidal disease for a century. Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d8f3e8c67b0c3efdd76a75f20519eb
https://hdl.handle.net/10453/163644
https://hdl.handle.net/10453/163644