Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kay Katada"'
Autor:
Louis R. Parham, Patrick A. Williams, Kay Katada, Shaneice K. Nettleford, Priya Chatterji, Kofi K. Acheampong, Charles H. Danan, Xianghui Ma, Lauren A. Simon, Kaitlyn E. Naughton, Rei Mizuno, Tatiana Karakasheva, Emily A. McMillan, Kelly A. Whelan, Donita C. Brady, Sydney M. Shaffer, Kathryn E. Hamilton
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 3, Pp 439-451 (2024)
Background & Aims: The intestinal epithelium interfaces with a diverse milieu of luminal contents while maintaining robust digestive and barrier functions. Facultative intestinal stem cells are cells that survive tissue injury and divide to re-establ
Externí odkaz:
https://doaj.org/article/2d55833f363e489b8c29b533990b04ea
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionLeptin inhibits insulin secretion from isolated islets from multiple species, but the cell type that mediates this process remains elusive. Several mouse models have been used to explore this question. Ablation of the leptin receptor (Lep
Externí odkaz:
https://doaj.org/article/af902a1448a44e28be6ae02936fac204
Autor:
Michael A. Schumacher, Cambrian Y. Liu, Kay Katada, Megan H. Thai, Jonathan J. Hsieh, Britany J. Hansten, Amanda Waddell, Michael J. Rosen, Mark R. Frey
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 4, Pp 971-984 (2023)
Background & Aims: Deep crypt secretory (DCS) cells are a critical component of the colonic stem cell niche. However, the regulatory mechanisms controlling DCS cell numbers and function are not well understood. Sprouty2 is an inflammation-responsive
Externí odkaz:
https://doaj.org/article/0db920d5c1054969a72b7ab89e630e78
Autor:
Michael A. Schumacher, Jonathan J. Hsieh, Cambrian Y. Liu, Keren L. Appel, Amanda Waddell, Dana Almohazey, Kay Katada, Jessica K. Bernard, Edie B. Bucar, Safina Gadeock, Kathryn M. Maselli, M. Kay Washington, Tracy C. Grikscheit, David Warburton, Michael J. Rosen, Mark R. Frey
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Dynamic regulation of colonic secretory cell numbers is a critical component of the response to intestinal injury and inflammation. Here, the authors show that loss of the intracellular signalling regulator Sprouty2 in the intestinal epithelial cells
Externí odkaz:
https://doaj.org/article/52880ff6d53e4e2d9bd21438503b7553
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 324:G91-G98
The profound complexity of the intestinal mucosa demands a spatial approach to the study of gut transcriptomics. Although single-cell RNA sequencing has revolutionized our ability to survey the diverse cell types of the intestine, knowledge of cell t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c2c3c24b99e19b4833d530705cd49d
https://doi.org/10.1152/ajpgi.00191.2022
https://doi.org/10.1152/ajpgi.00191.2022
Autor:
Charles H. Danan, Kaitlyn E. Naughton, Katharina E. Hayer, Sangeevan Vellappan, Emily A. McMillan, Yusen Zhou, Rina Matsuda, Shaneice K. Nettleford, Kay Katada, Louis R. Parham, Xianghui Ma, Afrah Chowdhury, Benjamin J. Wilkins, Premal Shah, Matthew D. Weitzman, Kathryn E. Hamilton
Intestinal epithelial transit amplifying cells are essential stem progenitors required for intestinal homeostasis, but their rapid proliferation renders them vulnerable to DNA damage from radiation and chemotherapy. Despite their critical roles in in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ba4e1d29349598369deb0938fa2c80
https://doi.org/10.1101/2023.04.06.535853
https://doi.org/10.1101/2023.04.06.535853
Publikováno v:
bioRxiv
The transcription factor FOXM1 regulates β-cell proliferation and insulin secretion. Our previous work demonstrates that expressing an activated form of FOXM1 (FOXM1*) in β cells increases β-cell proliferation and mass in aged male mice. Additiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c982208f683951cc8d941756f7529014
https://doi.org/10.1101/2023.01.12.523673
https://doi.org/10.1101/2023.01.12.523673
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8edd27c111ba6b2b7a8410be7c4ba89d
https://doi.org/10.1096/fasebj.2022.36.s1.r5010
https://doi.org/10.1096/fasebj.2022.36.s1.r5010
Autor:
Louis R. Parham, Patrick A. Williams, Priya Chatterji, Kofi K. Acheampong, Charles H. Danan, Kay Katada, Xianghui Ma, Lauren A. Simon, Kaitlyn E. Naughton, Rei Mizuno, Tatiana Karakasheva, Emily A. McMillan, Kelly A. Whelan, Donita C. Brady, Sydney M. Shaffer, Kathryn E. Hamilton
Homeostatic tissue maintenance requires coordinated regulation of metabolic processes including macroautophagy/autophagy. Autophagy dysregulation underlies numerous human diseases. Our prior work revealed that the RNA binding protein IGF2BP1/IMP1 bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e81235c991a2c078f486f90778a5711
https://doi.org/10.1101/2022.02.28.482365
https://doi.org/10.1101/2022.02.28.482365
Autor:
Edie B Bucar, Jonathan J. Hsieh, Amanda Waddell, Mark R. Frey, Kathryn M. Maselli, Safina Gadeock, Michael A. Schumacher, Jessica K. Bernard, Dana Almohazey, Kay Katada, Michael J. Rosen, M. Kay Washington, Cambrian Y. Liu, Keren Appel, David Warburton, Tracy C. Grikscheit
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Dynamic regulation of intestinal cell differentiation is crucial for both homeostasis and the response to injury or inflammation. Sprouty2, an intracellular signaling regulator, controls pathways including PI3K and MAPKs that are implicated in differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8dc0b79d9effcb3b465e035b6d4766a
http://europepmc.org/articles/PMC7864916
http://europepmc.org/articles/PMC7864916