Metabolic responses to mild cold acclimation in type 2 diabetes patients

Autor: Carlijn M. E. Remie, Michiel P. B. Moonen, Kay H. M. Roumans, Emmani B. M. Nascimento, Anne Gemmink, Bas Havekes, Gert Schaart, Esther Kornips, Peter J. Joris, Vera B. Schrauwen-Hinderling, Joris Hoeks, Sander Kersten, Matthijs K. C. Hesselink, Esther Phielix, Wouter D. van Marken Lichtenbelt, Patrick Schrauwen

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)

Cold acclimation has been shown to have beneficial metabolic effects, including improved insulin sensitivity in patients with type 2 diabetes. Here the authors show that a mild cold acclimation regiment during which overt shivering was prevented did

Externí odkaz: https://doaj.org/article/1c9d9177ddf8413ba3d5b7a5b26199f5

Three weeks of time-restricted eating improves glucose homeostasis in adults with type 2 diabetes but does not improve insulin sensitivity: a randomised crossover trial

Autor: Charlotte Andriessen, Ciarán E. Fealy, Anna Veelen, Sten M. M. van Beek, Kay H. M. Roumans, Niels J. Connell, Julian Mevenkamp, Esther Moonen-Kornips, Bas Havekes, Vera B. Schrauwen-Hinderling, Joris Hoeks, Patrick Schrauwen

Publikováno v: Diabetologia, 65(10):s00125-022-05752-z, 1710-1720. Springer, Cham

Aims/hypothesis Time-restricted eating (TRE) is suggested to improve metabolic health by limiting food intake to a defined time window, thereby prolonging the overnight fast. This prolonged fast is expected to lead to a more pronounced depletion of h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996d5a7fa78f4465d3b92b5853aa9ef3
https://doi.org/10.1007/s00125-022-05752-z

Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

Autor: Patrick Schrauwen, Riekelt H. Houtkooper, Michiel P.B. Moonen, Johan Auwerx, Bas Havekes, Joris Hoeks, Hyung L. Elfrink, Esther Phielix, Esther Lutgens, Suzanne A. B. M. Aarts, Niels J. Connell, Vera H. W. de Wit, Kay H. M. Roumans, Julian Mevenkamp, Tineke van de Weijer, Vera B. Schrauwen-Hinderling, Carlijn M. E. Remie, Lucas Lindeboom, Bauke V. Schomakers, Rubén Zapata-Pérez

Publikováno v: American Journal of Clinical Nutrition, 112(2), 413-426. Oxford University Press
American journal of clinical nutrition, 112(2), 413-426. American Society for Nutrition
The American Journal of Clinical Nutrition

Background: Nicotinamide riboside (NR) is an NAD(+) precursor that boosts cellular NAD(+) concentrations. Preclinical studies have shown profound metabolic health effects after NR supplementation.
Objectives: We aimed to investigate the effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56be3b6ee2771f0f66e56bb2d722920
https://doi.org/10.1093/ajcn/nqaa072

Metabolic responses to mild cold acclimation in type 2 diabetes patients

Autor: Sander Kersten, Wouter D. van Marken Lichtenbelt, Peter J. Joris, Carlijn M. E. Remie, Esther Phielix, Patrick Schrauwen, Esther Kornips, Michiel P.B. Moonen, Matthijs K. C. Hesselink, Emmani B.M. Nascimento, Gert Schaart, Joris Hoeks, Kay H. M. Roumans, Anne Gemmink, Bas Havekes, Vera B. Schrauwen-Hinderling

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications, 12(1)
Nature Communications 12 (2021) 1
Nature Communications, 12(1):1516. Nature Publishing Group

Mild cold acclimation for 10 days has been previously shown to markedly improve insulin sensitivity in patients with type 2 diabetes. Here we show in a single-arm intervention study (Trialregister.nl ID: NL4469/NTR5711) in nine patients with type 2 d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7cb56e36c3ec963db2516b38e205254
https://doi.org/10.1038/s41467-021-21813-0

Effects of dietary macronutrients on liver fat content in adults: a systematic review and meta-analysis of randomized controlled trials

Autor: Vera B. Schrauwen-Hinderling, Babette G. de Roos, Harry P. F. Peters, Esther Winters-van Eekelen, Marjan Alssema, Peter L. Zock, Kay H. M. Roumans, Jan W. Schoones, Frits R. Rosendaal, Inge Verkouter, Patrick Schrauwen, Olaf M. Dekkers, Renée de Mutsert

Publikováno v: European Journal of Clinical Nutrition. SPRINGERNATURE
European Journal of Clinical Nutrition
Winters-van Eekelen, E, Verkouter, I, Peters, H P F, Alssema, M, de Roos, B G, Schrauwen-Hinderling, V B, Roumans, K H M, Schoones, J W, Zock, P L, Schrauwen, P, Rosendaal, F R, Dekkers, O M & de Mutsert, R 2021, ' Effects of dietary macronutrients on liver fat content in adults : a systematic review and meta-analysis of randomized controlled trials ', European Journal of Clinical Nutrition, vol. 75, no. 4, pp. 588-601 . https://doi.org/10.1038/s41430-020-00778-1

Dietary macronutrient composition may affect hepatic liver content and its associated diseases, but the results from human intervention trials have been equivocal or underpowered. We aimed to assess the effects of dietary macronutrient composition on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98f4234aa36cd0867f5730aaa93c3d5
https://doi.org/10.1038/s41430-020-00778-1