Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Kay E. Gurley"'
Autor:
Goldie Y.L. Lui, Reid Shaw, Franz X. Schaub, Isabella N. Stork, Kay E. Gurley, Caroline Bridgwater, Robert L. Diaz, Rachele Rosati, Hallie A. Swan, Tan A. Ince, Thomas C. Harding, Vijayakrishna K. Gadi, Barbara A. Goff, Christopher J. Kemp, Elizabeth M. Swisher, Carla Grandori
Publikováno v:
EBioMedicine, Vol 60, Iss , Pp 102988- (2020)
Background: Homologous recombination deficiencies (HRD) are present in approximately half of epithelial ovarian cancers, for which PARP inhibitors (PARPi) are becoming a preferred treatment option. However, a considerable proportion of these carcinom
Externí odkaz:
https://doaj.org/article/3e5e8f98aab5402f8b8ee8783a2b4b38
Autor:
Christopher J. Kemp, James M. Moore, Russell Moser, Brady Bernard, Matt Teater, Leslie E. Smith, Natalia A. Rabaia, Kay E. Gurley, Justin Guinney, Stephanie E. Busch, Rita Shaknovich, Victor V. Lobanenkov, Denny Liggitt, Ilya Shmulevich, Ari Melnick, Galina N. Filippova
Publikováno v:
Cell Reports, Vol 7, Iss 4, Pp 1020-1029 (2014)
Epigenetic alterations, particularly in DNA methylation, are ubiquitous in cancer, yet the molecular origins and the consequences of these alterations are poorly understood. CTCF, a DNA-binding protein that regulates higher-order chromatin organizati
Externí odkaz:
https://doaj.org/article/48463119a5594710b0d33483242f11b5
Autor:
Carla Grandori, Christopher J. Kemp, Martin Morgan, Jerry Davison, Heather L. Howie, Kay E. Gurley, Kristin Robinson, Masafumi Toyoshima, Russell Moser
PDF file - 101K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae730dd98105a2e078abfa80f9b64cc9
https://doi.org/10.1158/1541-7786.22516593
https://doi.org/10.1158/1541-7786.22516593
Autor:
Carla Grandori, Christopher J. Kemp, Martin Morgan, Jerry Davison, Heather L. Howie, Kay E. Gurley, Kristin Robinson, Masafumi Toyoshima, Russell Moser
PDF file - 502K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ac3df4f5addd479fac2d3999b85d3f
https://doi.org/10.1158/1541-7786.22516599
https://doi.org/10.1158/1541-7786.22516599
Autor:
Christopher J. Kemp, Carla Grandori, Elizabeth M. Swisher, Tan A. Ince, Robert L. Diaz, Rachele Rosati, Grace Durenberger, Kay E. Gurley, Russell Moser, Reid Shaw, Goldie Y.L. Lui, Shogo Shigeta
Supplementary Figure 2. Gene Ontology (GO) enrichment analysis indicates OCI-C5x cells are more vulnerable to epigenetic interventions than OCI-P5x cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2354bb286dbcd1d1d9e63161bd05f9
https://doi.org/10.1158/1535-7163.22522126.v1
https://doi.org/10.1158/1535-7163.22522126.v1
Autor:
Carla Grandori, Christopher J. Kemp, Martin Morgan, Jerry Davison, Heather L. Howie, Kay E. Gurley, Kristin Robinson, Masafumi Toyoshima, Russell Moser
PDF file - 114K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5149ea943b5b78af9988a53513c213a1
https://doi.org/10.1158/1541-7786.22516596
https://doi.org/10.1158/1541-7786.22516596
Autor:
Carla Grandori, Christopher J. Kemp, Martin Morgan, Jerry Davison, Heather L. Howie, Kay E. Gurley, Kristin Robinson, Masafumi Toyoshima, Russell Moser
PDF file - 5.8MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e59c01ea6bbc9b9c140f58446fea2cd
https://doi.org/10.1158/1541-7786.22516584.v1
https://doi.org/10.1158/1541-7786.22516584.v1
Autor:
Carla Grandori, Christopher J. Kemp, Martin Morgan, Jerry Davison, Heather L. Howie, Kay E. Gurley, Kristin Robinson, Masafumi Toyoshima, Russell Moser
MYC-induced DNA damage is exacerbated in WRN-deficient cells, leading to replication stress and accelerated cellular senescence. To determine whether WRN deficiency impairs MYC-driven tumor development, we used both xenograft and autochthonous tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e0021c712f0ebcdd70633a6a6d28ec
https://doi.org/10.1158/1541-7786.c.6541422.v1
https://doi.org/10.1158/1541-7786.c.6541422.v1
Autor:
Christopher J. Kemp, Carla Grandori, Elizabeth M. Swisher, Tan A. Ince, Robert L. Diaz, Rachele Rosati, Grace Durenberger, Kay E. Gurley, Russell Moser, Reid Shaw, Goldie Y.L. Lui, Shogo Shigeta
Ovarian clear cell carcinoma (OCCC) is a rare, chemo-resistant subtype of ovarian cancer. To identify novel therapeutic targets and combination therapies for OCCC, we subjected a set of patient-derived ovarian cancer cell lines to arrayed high-throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ed4423984942ae5dd6f4830e5213cd
https://doi.org/10.1158/1535-7163.c.6543286.v1
https://doi.org/10.1158/1535-7163.c.6543286.v1
Autor:
Carla Grandori, Christopher J. Kemp, Martin Morgan, Jerry Davison, Heather L. Howie, Kay E. Gurley, Kristin Robinson, Masafumi Toyoshima, Russell Moser
PDF file - 164K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274024f2c41f89489db07c56a6fc90b0
https://doi.org/10.1158/1541-7786.22516602
https://doi.org/10.1158/1541-7786.22516602