Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kaxi Yu"'
Publikováno v:
Crystals, Vol 12, Iss 4, p 550 (2022)
Baloxavir marboxil (BXM) is a new blockbuster FDA-approved anti-influenza virus agent. However, its poor solubility has limited its oral bioavailability. In this study, BXM was crystallized from several organic solvents, obtaining three polymorphs, a
Externí odkaz:
https://doaj.org/article/e32e06611af547ee8fec3b93fb24b03e
Autor:
Yijie Lou, Kaxi Yu, Xiajun Wu, Zhaojun Wang, Yusheng Cui, Hanxiao Bao, Jianwei Wang, Xiurong Hu, Yunxi Ji, Guping Tang
Publikováno v:
Molecules, Vol 26, Iss 18, p 5722 (2021)
Resveratrol (RSV) and polydatin (PD) have been widely used to treat several chronic diseases, such as atherosclerosis, pulmonary fibrosis, and diabetes, among several others. However, their low solubility hinders their further applications. In this w
Externí odkaz:
https://doaj.org/article/e199e939132d47d1a903fefd4321ee9b
Publikováno v:
Molecules, Vol 26, Iss 11, p 3469 (2021)
The dissolution rate is the rate-limiting step for Biopharmaceutics Classification System (BCS) class II drugs to enhance their in vivo pharmacokinetic behaviors. There are some factors affecting the dissolution rate, such as polymorphism, particle s
Externí odkaz:
https://doaj.org/article/db4ca8a4411f43eb9640b2efb9d67d70
Publikováno v:
Molecules, Vol 26, Iss 2, p 298 (2021)
Canagliflozin (CG) was a highly effective, selective and reversible inhibitor of sodium-dependent glucose co-transporter 2 developed for the treatment of type 2 diabetes mellitus. The crystal structure of CG monohydrate (CG-H2O) was reported for the
Externí odkaz:
https://doaj.org/article/7e89df25681a4c8780fe081e4a4a8ea6
Publikováno v:
Crystals, Vol 9, Iss 11, p 556 (2019)
Drugs with poor biopharmaceutical performance are the main obstacle to the development and design of medicinal preparations. The anisotropic surface chemistry of different surfaces on the crystal influences its physical and chemical properties, such
Externí odkaz:
https://doaj.org/article/0c7d3dfbc7794722bc79ef81bde22214
Publikováno v:
Crystal Growth & Design. 23:2905-2915
Publikováno v:
Nanomaterials and Nanotechnology in Medicine. :427-445
Publikováno v:
Crystal Growth & Design. 22:4421-4430
Autor:
Chander Amgoth, Yunhong He, Shuping Wang, Kaxi Yu, Jianwei Wang, Xiurong Hu, Jun Zhou, Guping Tang, Hongzhen Bai
Publikováno v:
ACS Applied Polymer Materials. 4:1675-1687
Autor:
Yunhong He, Jianwei Wang, Shuping Wang, Kaxi Yu, Jun Zhou, Jinqiang Wang, Guping Tang, Zhen Gu, Hongzhen Bai
Publikováno v:
Nano Today. 48:101700