Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Kawula, T H"'
Autor:
Chen, C.-j., Roberts, L. M., Cumming, R. I., Tuladhar, S., Riebe, K. J., Kawula, T. H., Frelinger, J. A., Steele, S. P., Seay, S., Sempowski, G. D., Frothingham, R.
The adaptive immune response to Francisella tularensis is dependent on the route of inoculation. Intradermal inoculation with the F. tularensis live vaccine strain (LVS) results in a robust Th1 response in the lungs, whereas intranasal inoculation pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ef1317b1c0fdaff27fbb77c7b41421b
Autor:
Steele, S. P., Fuller, J. R., Miller, C. N., Kijek, T. M., LoVullo, E. D., Taft-Benz, S. A., Kawula, T. H., Brunton, J. C., Richardson, A. R.
Pantothenate, commonly referred to as vitamin B5, is an essential molecule in the metabolism of living organisms and forms the core of coenzyme A. Unlike humans, some bacteria and plants are capable of de novo biosynthesis of pantothenate, making thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c72286cecaaa89aa83c7b66615a7020
Francisella tularensis is a Gram-negative coccobacillus and is the etiological agent of the disease tularemia. Expression of the cytoplasmic membrane protein RipA is required for Francisella replication within macrophages and other cell types; howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e8a4bda0e60896654f9181bcc6e776c
Autor:
Kijek, T. M., Fuller, J. R., Miller, C. N., Huang, M. T. H., Kawula, T. H., Mortensen, B. L., Taft-Benz, S.
Francisella tularensis is a highly virulent Gram-negative bacterium and is the etiological agent of the disease tularemia. IclR, a presumed transcriptional regulator, is required for full virulence of the animal pathogen, F. tularensis subspecies nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448bfc9df0fc7288bab9af126c3b6dd3
Francisella tularensis is a highly virulent bacterial pathogen that invades and replicates within numerous host cell types, including macrophages and epithelial cells. In an effort to better understand this process, we screened a transposon insertion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdd73e20796fdc2fc10d4a1c253d5120
Francisella tularensis, a gram-negative facultative intracellular bacterial pathogen, causes disseminating infections in humans and other mammalian hosts. Macrophages and other monocytes have long been considered the primary site of F. tularensis rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a96c7516b5f423f056175a96cc116f47
Two key routes of Francisella tularensis infection are through the skin and airway. We wished to understand how the route of inoculation influenced the primary acute adaptive immune response. We show that an intranasal inoculation of the F. tularensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38054daa9d59fa1facc8bcb1542056d2
Francisella tularensis is a gram-negative pathogen that causes life-threatening infections in humans and has potential for use as a biological weapon. The genetic basis of the F. tularensis virulence is poorly understood. This study screened a total
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7d36b74da20085fbf78ca6707621874
Francisella tularensis replicates in macrophages and dendritic cells, but interactions with other cell types have not been well described. F. tularensis LVS invaded and replicated within alveolar epithelial cell lines. Following intranasal inoculatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccaefaa5403b9723996294a8f07002aa
Autor:
Katz, B. P., Cole, L. E., Orndorff, P. E., Kawula, T. H., Fulcher, R. A., Spinola, S. M., Fortney, K. R., Toffer, K. L., Janowicz, D. M.
Haemophilus ducreyi, the etiologic agent of the sexually transmitted genital ulcer disease chancroid, has been shown to associate with dermal collagen fibers within infected skin lesions. Here we describe NcaA, a previously uncharacterized outer memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42b000ab720ed03aa50a3e4ea3d61f6f