Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Kavon Rezai-Zadeh"'
Autor:
Kavon Rezai-Zadeh, Sanghou Yu, Yanyan Jiang, Amanda Laque, Candice Schwartzenburg, Christopher D. Morrison, Andrei V. Derbenev, Andrea Zsombok, Heike Münzberg
Publikováno v:
Molecular Metabolism, Vol 3, Iss 7, Pp 681-693 (2014)
Objective: Leptin responsive neurons play an important role in energy homeostasis, controlling specific autonomic, behavioral, and neuroendocrine functions. We have previously identified a population of leptin receptor (LepRb) expressing neurons with
Externí odkaz:
https://doaj.org/article/7169261937564c9780cd6300b50cabcf
Autor:
Ching Wen Tseng, Juan Carlos Biancotti, Bethany L Berg, David Gate, Stacey L Kolar, Sabrina Müller, Maria D Rodriguez, Kavon Rezai-Zadeh, Xuemo Fan, David O Beenhouwer, Terrence Town, George Y Liu
Publikováno v:
PLoS Pathogens, Vol 11, Iss 11, p e1005292 (2015)
Staphylococcus aureus is a leading cause of skin and soft-tissue infections worldwide. Mice are the most commonly used animals for modeling human staphylococcal infections. However a supra-physiologic S. aureus inoculum is required to establish gross
Externí odkaz:
https://doaj.org/article/d46d1dd4080f435ab935ec60a432f84c
Autor:
She-Qing Zhang, Darrell Sawmiller, Song Li, Kavon Rezai-Zadeh, Huayan Hou, Shufeng Zhou, Douglas Shytle, Brian Giunta, Frank Fernandez, Takashi Mori, Jun Tan
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71913 (2013)
Our previous studies showed that the green tea-derived polyphenolic compound (-)-epigallocatechin-3 gallate (EGCG) reduces amyloid-β (Aβ) production in both neuronal and mouse Alzheimer's disease (AD) models in concert with activation of estrogen r
Externí odkaz:
https://doaj.org/article/7087004fe49c4cbf8c8beee193770d7f
Autor:
Yanyan, Jiang, Kavon, Rezai-Zadeh, Lucie D, Desmoulins, Heike, Muenzberg, Andrei V, Derbenev, Andrea, Zsombok
Publikováno v:
Autonomic Neuroscience. 245:103058
Brown adipose tissue (BAT) contributes to energy homeostasis via nonshivering thermogenesis. The BAT is densely innervated by the sympathetic nervous system (SNS) and activity of pre-autonomic neurons modulates the sympathetic outflow. Leptin, an adi
Autor:
Andrei V. Derbenev, Sangho Yu, Andrea Zsombok, Kavon Rezai-Zadeh, Yanyan Jiang, Christopher D. Morrison, Heike Münzberg, Hans-Rudolf Berthoud, Emily Qualls-Creekmore
Publikováno v:
The Journal of Neuroscience. 36:5034-5046
The preoptic area (POA) regulates body temperature, but is not considered a site for body weight control. A subpopulation of POA neurons express leptin receptors (LepRbPOAneurons) and modulate reproductive function. However, LepRbPOAneurons project t
Autor:
Javier Rodriguez, Marie-Victoire Guillot-Sestier, Kwok Wai Im, Alexander W. Vesling, Kavon Rezai-Zadeh, Terrence Town
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
Kavon Rezai-Zadeh, Kevin R. Doty, David Gate, Terrence Town, Javier Rodriguez, Marie-Victoire Guillot-Sestier, Brian P. Leung
Publikováno v:
Neuron. 85(3):534-548
Summary The impact of inflammation suppressor pathways on Alzheimer's disease (AD) evolution remains poorly understood. Human genetic evidence suggests involvement of the cardinal anti-inflammatory cytokine, interleukin-10 ( IL10 ). We crossed the AP
Publikováno v:
The American Journal of Pathology. 184:2855-2861
Activated microglia are associated with amyloid plaques in transgenic mouse models of cerebral amyloidosis and in human Alzheimer disease; yet, their implication in Alzheimer disease pathogenesis remains unclear. It has been suggested that microglia
Autor:
Michael J. Keenan, Kavon Rezai-Zadeh, Jianping Ye, Heike Münzberg, Diana Coulon, Hongyun Lu, Hans-Rudolf Berthoud, Zheng Hao
Publikováno v:
International Journal of Obesity. 39:798-805
Weight regain contributes to the therapeutic failure in 15-20% of type 2 diabetic patients after Roux-en-Y gastric bypass surgery (RYGB), and the mechanism remains largely unknown. This study was conducted to explore the mechanism of weight regain.Wi
Autor:
Kavon Rezai-Zadeh, Heike Münzberg
Publikováno v:
Physiology & Behavior. 121:49-55
The adipocyte derived hormone leptin acts in the brain to regulate body weight, food intake and energy expenditure. Even though it is well accepted that leptin regulates energy expenditure at least in part by modulating thermogenesis, the exact mecha