Perinatal maternal exposure to high-dose sodium phenobarbital in the modified Comparative Thyroid Assay: no significant reduction in thyroid hormones in pups despite notable effects in dams.

Autor: Hidenori Suto^1,2, Keiko Ogata¹, Kenta Minami¹, Akira Sato³, Naruto Tomiyama³, Tadashi Kosaka³, Hitoshi Hojo³, Naofumi Takahashi³, Hiroaki Aoyama³, Tomoya Yamada¹ yamadat8@sc.sumitomo-chem.co.jp

Publikováno v: Journal of Toxicological Sciences. 2024, Vol. 49 Issue 11, p509-529. 21p.

An automated computational data pipeline to rapidly acquire, score, and rank toxicological data for ecological hazard assessment.

Autor: Schaupp CM; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, USA.; US Environmental Protection Agency, Great Lakes Toxicology and Ecology Division, Center for Computational Toxicology and Exposure, Duluth, Minnesota, USA., Byrne G; General Dynamics Information Technology Inc., Supporting USEPA IV (MAINES) Contract, Research Triangle Park, North Carolina, USA., Chan M; USEPA, Center for Computational Toxicology and Exposure, Scientific Computing and Data Curation Division, Data Management and Mining Branch, Research Triangle Park, North Carolina, USA., Haggard DE; USEPA, Center for Computational Toxicology and Exposure, Scientific Computing and Data Curation Division, Data Management and Mining Branch, Research Triangle Park, North Carolina, USA., Hazemi M; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, USA.; US Environmental Protection Agency, Great Lakes Toxicology and Ecology Division, Center for Computational Toxicology and Exposure, Duluth, Minnesota, USA., Jankowski MD; USEPA, Region 10 Office, Laboratory Services & Applied Science Division, Risk Evaluation Branch, Seattle, Washington, USA., LaLone CA; US Environmental Protection Agency, Great Lakes Toxicology and Ecology Division, Center for Computational Toxicology and Exposure, Duluth, Minnesota, USA., LaTier A; USEPA, Region 10 Office, Laboratory Services & Applied Science Division, Risk Evaluation Branch, Seattle, Washington, USA., Mattingly KZ; Spec-Pro Professional Services, Duluth, Minnesota, USA., Olker JH; US Environmental Protection Agency, Great Lakes Toxicology and Ecology Division, Center for Computational Toxicology and Exposure, Duluth, Minnesota, USA., Renner J; USEPA, Scientific Computing and Data Curation Division, Center for Computational Toxicology and Exposure, Data Management and Mining Branch, Duluth, Minnesota, USA., Sharma B; USEPA, Center for Computational Toxicology and Exposure, Scientific Computing and Data Curation Division, Data Management and Mining Branch, Research Triangle Park, North Carolina, USA., Villeneuve DL; US Environmental Protection Agency, Great Lakes Toxicology and Ecology Division, Center for Computational Toxicology and Exposure, Duluth, Minnesota, USA.

Publikováno v: Integrated environmental assessment and management [Integr Environ Assess Manag] 2024 Nov; Vol. 20 (6), pp. 2203-2217. Date of Electronic Publication: 2024 May 16.

Update of the scientific opinion on tetrabromobisphenol A (TBBPA) and its derivatives in food.

Autor: Schrenk, Dieter (AUTHOR), Bignami, Margherita (AUTHOR), Bodin, Laurent (AUTHOR), Chipman, James Kevin (AUTHOR), del Mazo, Jesús (AUTHOR), Grasl‐Kraupp, Bettina (AUTHOR), Hogstrand, Christer (AUTHOR), Hoogenboom, Laurentius (AUTHOR), Leblanc, Jean‐Charles (AUTHOR), Nebbia, Carlo Stefano (AUTHOR), Nielsen, Elsa (AUTHOR), Ntzani, Evangelia (AUTHOR), Petersen, Annette (AUTHOR), Sand, Salomon (AUTHOR), Schwerdtle, Tanja (AUTHOR), Wallace, Heather (AUTHOR), Benford, Diane (AUTHOR), Hart, Andy (AUTHOR), Schroeder, Henri (AUTHOR), Rose, Martin (AUTHOR)

Publikováno v: EFSA Journal. Jul2024, Vol. 22 Issue 7, p1-146. 146p.

In vitro teratology

Autor: Schwetz, B A, Morrissey, R E, Welsch, F, Kavlock, R A

Publikováno v: Environmental Health Perspectives

The purpose of this conference was to reevaluate the need for and use of in vitro teratology assays; to examine the validation process for in vitro tests; and to discuss progress in the validation of in vitro teratology screens. Participants enthusia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f1bef6bcdf6b9439c7612f970fff6f7a
http://europepmc.org/articles/PMC1567960

A Comprehensive Review of Free Radicals, Oxidative Stress, and Antioxidants: Overview, Clinical Applications, Global Perspectives, Future Directions, and Mechanisms of Antioxidant Activity of Flavonoid Compounds.

Autor: Tumilaar, Sefren Geiner¹ (AUTHOR), Hardianto, Ari¹ (AUTHOR), Dohi, Hirofumi² (AUTHOR), Kurnia, Dikdik¹ (AUTHOR)

Publikováno v: Journal of Chemistry. 5/31/2024, Vol. 2024, p1-21. 21p.