Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Kavithalakshmi Sataranatarajan"'
Autor:
Kavithalakshmi Sataranatarajan, Shishir Adhikari, Ngoc Nguyen, Madhusudhanan Narasimhan, Jyoti Balani, Alagarraju Muthukumar
Publikováno v:
Diagnostics, Vol 14, Iss 16, p 1744 (2024)
Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal (GI) tract. Fecal calprotectin (fCAL) is a noninvasive laboratory test used in the diagnosis and monitoring of IBDs such as Crohn’s disease and ulcera
Externí odkaz:
https://doaj.org/article/ef54da33105b48ac803ad3b0eb6c7b4e
Autor:
Madhusudhanan Narasimhan, Alagarraju Muthukumar, Kavithalakshmi Sataranatarajan, Lenin Mahimainathan, Luke Mahan, Irina Timofte, Srinivas Bollineni, John Joerns, Song Zhang, April Gorman, Amit Banga, Manish Mohanka, Fernando Torres, Adrian Lawrence, Mohanakumar Thalachallour, Vaidehi Kaza
Publikováno v:
Viruses, Vol 15, Iss 10, p 2045 (2023)
The presence of a certain group of auto-antibodies (AAbs) is known to correlate with the severity of COVID-19. It is, however, unknown if such AAbs are prevalent and impact COVID-19-related outcomes in lung transplant recipients (LTRs) who are immuno
Externí odkaz:
https://doaj.org/article/dd17f06550e441f5a1188343701ffae4
Autor:
Rizwan Qaisar, Shylesh Bhaskaran, Rojina Ranjit, Kavithalakshmi Sataranatarajan, Pavithra Premkumar, Kendra Huseman, Holly Van Remmen
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 68-74 (2019)
Molecular targets to reduce muscle weakness and atrophy due to oxidative stress have been elusive. Here we show that activation of Sarcoplasmic Reticulum (SR) Ca2+ ATPase (SERCA) with CDN1163, a novel small molecule allosteric SERCA activator, amelio
Externí odkaz:
https://doaj.org/article/1109ff0a1f05410a8f10d187f34502b4
Autor:
Jacob L. Brown, David E. Lee, Megan E. Rosa‐Caldwell, Lemuel A. Brown, Richard A. Perry, Wesley S. Haynie, Kendra Huseman, Kavithalakshmi Sataranatarajan, Holly Van Remmen, Tyrone A. Washington, Michael P. Wiggs, Nicholas P. Greene
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 9, Iss 5, Pp 987-1002 (2018)
Abstract Background Cancer cachexia occurs in approximately 80% of cancer patients and is a key contributor to cancer‐related death. The mechanisms controlling development of tumour‐induced muscle wasting are not fully elucidated. Specifically, t
Externí odkaz:
https://doaj.org/article/34e2fe6cc5db40f29d728458fc6773bb
Autor:
Gavin Pharaoh, Kavithalakshmi Sataranatarajan, Kaitlyn Street, Shauna Hill, Jake Gregston, Bumsoo Ahn, Caroline Kinter, Michael Kinter, Holly Van Remmen
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Many Amyotrophic Lateral Sclerosis (ALS) patients experience hypermetabolism, or an increase in measured vs. calculated metabolic rate. The cause of hypermetabolism and the effects on neuronal metabolism in ALS are currently unknown, but the efficacy
Externí odkaz:
https://doaj.org/article/fb0c1e0437db4566b4d13cf17819ea20
Publikováno v:
Redox Biology, Vol 8, Iss C, Pp 430-438 (2016)
Mice deficient in the electron transport chain (ETC) complex IV assembly protein SURF1 have reduced assembly and activity of cytochrome c oxidase that is associated with an upregulation of components of the mitochondrial unfolded protein response (UP
Externí odkaz:
https://doaj.org/article/aa2fc58866764184added2e583834ed6
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Mitochondria are established essential regulators of cellular function and metabolism. Mitochondria regulate redox homeostasis, maintain energy (ATP) production through oxidative phosphorylation, buffer calcium levels, and control cell death through
Externí odkaz:
https://doaj.org/article/783c6cbbed8742eea2f74b52ff732f28
Autor:
Kavithalakshmi Sataranatarajan, Rizwan Qaisar, Carol Davis, Giorgos K. Sakellariou, Aphrodite Vasilaki, Yiqiang Zhang, Yuhong Liu, Shylesh Bhaskaran, Anne McArdle, Malcolm Jackson, Susan V. Brooks, Arlan Richardson, Holly Van Remmen
Publikováno v:
Redox Biology, Vol 5, Iss , Pp 140-148 (2015)
Our previous studies showed that adult (8 month) mice lacking CuZn-superoxide dismutase (CuZnSOD, Sod1KO mice) have neuromuscular changes resulting in dramatic accelerated muscle atrophy and weakness that mimics age-related sarcopenia. We have furthe
Externí odkaz:
https://doaj.org/article/68ada85f180744b49b4e7e265f79dec8
Autor:
Sergio Dominguez-Lopez, Bumsoo Ahn, Kavithalakshmi Sataranatarajan, Rojina Ranjit, Pavithra Premkumar, Holly Van Remmen, Michael J. Beckstead
Acute and neurotoxic regimens of METH are known to increase reactive oxygen species (ROS), affect redox homeostasis, and lead to cellular damage in dopamine neurons. However, functional changes induced by long-term METH self-administration on mitocho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b5fcc1b739dfd5899db3b022ef4abe9
https://doi.org/10.1101/2022.09.12.507550
https://doi.org/10.1101/2022.09.12.507550
Autor:
Sergio Dominguez-Lopez, Bumsoo Ahn, Kavithalakshmi Sataranatarajan, Rojina Ranjit, Pavithra Premkumar, Holly Van Remmen, Michael J. Beckstead
Publikováno v:
Neuropharmacology. 227:109436
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adedae74b99d0f79905beaabdb8f12c0
https://doi.org/10.1016/j.neuropharm.2023.109436
https://doi.org/10.1016/j.neuropharm.2023.109436