Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Kavitha Sunassee"'
Autor:
Julia E. Blower, Jayanta K. Bordoloi, Alex Rigby, Matthew Farleigh, Jana Kim, Hugh O'Brien, Jonathan Jackson, Constantinos Poyiatzis, James Bezer, Kavitha Sunassee, Philip J. Blower, Lefteris Livieratos
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
Background: Multi-tracer PET/SPECT imaging enables different modality tracers to be present simultaneously, allowing multiple physiological processes to be imaged in the same subject, within a short time-frame. Fluorine-18 and technetium-99m, two com
Externí odkaz:
https://doaj.org/article/852703950763404891786400377a7ca0
Autor:
Saima Nawaz, Gregory E. D. Mullen, Kavitha Sunassee, Jayanta Bordoloi, Philip J. Blower, James R. Ballinger
Publikováno v:
EJNMMI Research, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Background Labelling proteins with gallium-68 using bifunctional chelators is often problematic because of unsuitably harsh labelling conditions such as low pH or high temperature and may entail post-labelling purification. To determine whet
Externí odkaz:
https://doaj.org/article/1eba01461c5641209fa69a4900294b03
Autor:
Ehsan Sharif-Paghaleh, Kavitha Sunassee, Richard Tavaré, Kulachelvy Ratnasothy, Alexander Koers, Niwa Ali, Rowa Alhabbab, Philip J Blower, Robert I Lechler, Lesley A Smyth, Gregory E Mullen, Giovanna Lombardi
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25857 (2011)
Regulatory T cells (Tregs) were identified several years ago and are key in controlling autoimmune diseases and limiting immune responses to foreign antigens, including alloantigens. In vivo imaging techniques including intravital microscopy as well
Externí odkaz:
https://doaj.org/article/0ea4ae1396b74ba491e13c829f5520f6
Autor:
Johanna Pruller, Truc Thuy Pham, Julia E. Blower, Putthiporn Charoenphun, Alessia Volpe, Kavitha Sunassee, Gregory E. D. Mullen, Philip J. Blower, Richard A. G. Smith, Michelle T. Ma
Publikováno v:
RSC Chemical Biology. 4:65-73
An indium-111-labelled peptide binds to myeloma cells, enabling SPECT imaging of myeloma cell accumulation in lungs after intravenous administration. This is the first report of a radiolabelled cell-membrane binding peptide for cell tracking.
Autor:
Martin L. Read, Katie Brookes, Ling Zha, Selvambigai Manivannan, Jana Kim, Merve Kocbiyik, Alice Fletcher, Caroline M. Gorvin, George Firth, Gilbert O. Fruhwirth, Juan P. Nicola, Sissy Jhiang, Matthew D. Ringel, Moray J. Campbell, Kavitha Sunassee, Philip J. Blower, Kristien Boelaert, Hannah R. Nieto, Vicki E. Smith, Christopher J. McCabe
The sodium/iodide symporter (NIS) frequently shows diminished plasma membrane (PM) targeting in differentiated thyroid cancer (DTC), resulting in suboptimal radioiodide (RAI) treatment and poor prognosis. The mechanisms which govern the endocytosis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0a757baf79e22f16a69b80be8a04fd2
https://doi.org/10.1101/2023.05.22.541733
https://doi.org/10.1101/2023.05.22.541733
Autor:
Katie Brookes, Ling Zha, Jana Kim, Benjamin Small, Merve Kocbiyik, Selvambigai Manivannan, Vinodh Kannappan, Weiguang Wang, Kavitha Sunassee, Philip Blower, Hannah Nieto, Vicki Smith, Martin Read, Christopher Mccabe
Publikováno v:
Endocrine Abstracts.
Autor:
Ling Zha, Katie Brookes, Caitlin Thornton, Alice Fletcher, Jana Kim, Kavitha Sunassee, Philip J Blower, Hannah R Nieto, Vicki E Smith, Martin L Read, Christopher J McCabe
Publikováno v:
Endocrine Abstracts.
Autor:
Martin Read, Katie Brookes, Ling Zha, Jana Kim, Mehjabi Moolla, Merve Kocbiyik, Selvambigai Manivannan, Rachel Hoare, Vinodh Kannappan, Weiguang Wang, Kavitha Sunassee, Philip Blower, Hannah Nieto, Vicki Smith, Christopher McCabe
Publikováno v:
Endocrine Abstracts.
Autor:
Katie Brookes, Ling Zha, Jana Kim, Vinodh Kannappans, Weiguang Wang, Kavitha Sunassee, Philip J. Blower, Vicki E. Smith, Martin L. Read, Christopher J. McCabe
Publikováno v:
Cancer Research. 83:5053-5053
New drug approaches are urgently required to improve radioiodide (RAI) uptake for efficient ablation of thyroid cancer cells in RAI-refractory disease. Employing high-throughput screening of FDA-approved compounds we recently identified drugs capable
Autor:
Kavitha Sunassee, Teresa Sementa, Philip J. Blower, Joel Dunn, Jayanta Bordoloi, Antony D. Gee, Salvatore Bongarzone
Publikováno v:
Journal of Medicinal Chemistry
The water-soluble vitamin biotin is essential for cellular growth, development, and well-being, but its absorption, distribution, metabolism, and excretion are poorly understood. This paper describes the radiolabeling of biotin with the positron emis