Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kavitha N Rao"'
Autor:
Houda Z Elloumi, Nitsan Maharshak, Kavitha N Rao, Taku Kobayashi, Hyungjin S Ryu, Marcus Mühlbauer, Fengling Li, Christian Jobin, Scott E Plevy
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34172 (2012)
Nuclear factor of activated T cells (NFAT) plays a critical role in the development and function of immune and non-immune cells. Although NFAT is a central transcriptional regulator of T cell cytokines, its role in macrophage specific gene expression
Externí odkaz:
https://doaj.org/article/d51c08220d70414f8c907f36d88072a0
Publikováno v:
Blood. 122:2572-2581
The Ikaros gene (Ikzf1) encodes a family of zinc-finger transcription factors implicated in hematopoietic cell differentiation. Here we show that Ikaros suppresses the development of basophils, which are proinflammatory cells of the myeloid lineage.
Autor:
Kavitha N. Rao, Melissa A. Brown
Publikováno v:
Annals of the New York Academy of Sciences. 1143:83-104
Mast cells were discovered more than 100 years ago and until recently, have been considered renegades of the host with the sole purpose of perpetuating allergy. The discovery of mast cell-deficient mice that could be reconstituted with mast cells (th
Autor:
Scott E. Plevy, Aqila M. Mayle, Antonia R. Sepulveda, Leo E. Otterbein, Kavitha N. Rao, Refaat Hegazi
Publikováno v:
The Journal of Experimental Medicine
Heme oxygenase (HO)-1 and its metabolic product carbon monoxide (CO) play regulatory roles in acute inflammatory states. In this study, we demonstrate that CO administration is effective as a therapeutic modality in mice with established chronic coli
Autor:
Christian Jobin, Houda Z. Elloumi, Hyungjin Sally Ryu, Scott E. Plevy, Marcus Mühlbauer, Nitsan Maharshak, Kavitha N. Rao, Fengling Li, Taku Kobayashi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 3, p e34172 (2012)
PLoS ONE, Vol 7, Iss 3, p e34172 (2012)
Nuclear factor of activated T cells (NFAT) plays a critical role in the development and function of immune and non-immune cells. Although NFAT is a central transcriptional regulator of T cell cytokines, its role in macrophage specific gene expression
Autor:
Katsuyoshi Matsuoka, Scott E. Plevy, Bart Vanhaesebroeck, Erin C. Steinbach, Shehzad Z. Sheikh, Antonia R. Sepulveda, Fengling Li, Taku Kobayashi, Kavitha N. Rao, R. Balfour Sartor, Jennifer K. Uno
Background & Aims Innate immune responses are crucial for host defense against pathogens but need to be tightly regulated to prevent chronic inflammation. Initial characterization of mice with a targeted inactivating mutation in the p110δ subunit of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7a4f2a8ed01a2e0cda3295036924d3
https://europepmc.org/articles/PMC2967619/
https://europepmc.org/articles/PMC2967619/
Autor:
Kavitha N. Rao, Fengling Li, Chen Zhu, Scott E. Plevy, Curt M. Horvath, Khatuna Gagnidze, Huabao Xiong
Publikováno v:
The Journal of biological chemistry. 278(41)
Interleukin (IL)-12 is a heterodimeric cytokine that is critical for the development of a T-helper-1 immune response and immunity against intracellular pathogens. The IL-12 p40 gene product, expressed specifically in macrophages and dendritic cells,
Autor:
Fengling Li, Kavitha N. Rao, Jennifer K. Uno, Shehzad Z. Sheikh, Katsuyoshi Matsuoka, Scott E. Plevy
Publikováno v:
Gastroenterology. 136:A-168
Publikováno v:
The Journal of Immunology. 182:138.21-138.21
The transcription factor Ikaros has been implicated in the regulation of hematopoiesis at the level of T, B, NK and dendritic cells. In this study we examine the role of Ikaros in the development and differentiation of mast cells, using mice lacking
Pathologic prognostic factors and outcomes in patients with colon cancers with low lymph node yields
Publikováno v:
Gastroenterology. 124:A656