Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kavitha Bhasi"'
Publikováno v:
Clinical Drug Investigation
Background Overactive bladder (OAB) is often associated with a number of co-morbid medical conditions, including diabetes mellitus. This may necessitate several concomitant treatments, thus creating the potential for drug–drug interactions (DDIs).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f0f06f67a71a76817d9d807cb37851
https://doi.org/10.1007/s40261-012-0049-6
https://doi.org/10.1007/s40261-012-0049-6
Autor:
Kara Patrick, Bianca Weinstock-Guttman, Frederick Munschauer, Miriam Tamaño-Blanco, Kavitha Bhasi, Darlene Badgett, Rohit Bakshi, Joan Feichter, Murali Ramanathan, Miranda Minhas
Publikováno v:
Journal of Neuroimmunology. 205:113-125
Purpose To characterize gene expression in multiple sclerosis (MS) patients after the first dose and chronic dosing of 30 µg, once weekly, intramuscular interferon-β1a (IFN-β) and to delineate the pharmacogenomic differences between Good Responder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e503dbd09add6afcdbf2ec9b2580c71
https://doi.org/10.1016/j.jneuroim.2008.09.004
https://doi.org/10.1016/j.jneuroim.2008.09.004
Autor:
Murali Ramanathan, Bianca Weinstock-Guttman, Kavitha Bhasi, Robert Zivadinov, Miriam Tamaño-Blanco
Publikováno v:
Journal of Neuroimmunology. 182:236-239
The myxovirus resistance A (MXA) mRNA has been extensively investigated for assessing the biologic responses of multiple sclerosis (MS) patients to interferon-beta (IFN-beta) therapy. The objective of this study was to evaluate the associations betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d7266ee0a9f12d7d7cc54e0f1cd858
https://doi.org/10.1016/j.jneuroim.2006.10.011
https://doi.org/10.1016/j.jneuroim.2006.10.011
Publikováno v:
Bioinformatics. 22:1569-1576
Motivation: The size, dimensionality and the limited range of the data values make visualization of single nucleotide polymorphism (SNP) datasets challenging. The purpose of this study is to evaluate the usefulness of 3D VizStruct, a novel multi-dime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f6907e997a036024d1c700de9ae1df
https://doi.org/10.1093/bioinformatics/btl144
https://doi.org/10.1093/bioinformatics/btl144
Publikováno v:
Bioinformatics. 21:3873-3879
Purpose: To evaluate a semi-parametric, model-based approach for obtaining transcription rates from mRNA and protein expression. Methods: The transcription profile input was modeled using an exponential function of a cubic spline and the dynamics of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbcdb98d67838789a898ce8464d263a
https://doi.org/10.1093/bioinformatics/bti624
https://doi.org/10.1093/bioinformatics/bti624
Publikováno v:
Pharmaceutical Research. 21:777-780
Data visualization techniques for the pharmaceutical sciences have not been extensively investigated. The purpose of this study was to evaluate the usefulness of VizStruct, a multidimensional visualization tool, for applications in pharmacokinetics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380bbbeeae4f943bf61b976d96bfd4da
https://doi.org/10.1023/b:pham.0000026427.30177.61
https://doi.org/10.1023/b:pham.0000026427.30177.61
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England). 13(7)
Approximately 5—25% of interferon-β (IFN-β) treated multiple sclerosis (MS) patients develop anti-IFN-β neutralizing antibodies (NAb) but the patient-specific variables associated with the risk of developing anti-IFN-β antibodies are poorly und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb560eb5cd218013dbaa2fd2128da13b
https://pubmed.ncbi.nlm.nih.gov/17468449
https://pubmed.ncbi.nlm.nih.gov/17468449
Publikováno v:
Pharmaceutical research. 23(4)
This study was conducted to evaluate the applicability of SPLINDID, a semiparametric, model-based approach for obtaining transcription rates from the pharmacodynamics of mRNA expression. A nonparametric exponential cubic spline function was used to o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b3b3321f3cd1ba0dc4f114cb6fd35f
https://pubmed.ncbi.nlm.nih.gov/16550471
https://pubmed.ncbi.nlm.nih.gov/16550471
Publikováno v:
Nucleic Acids Research
The size, dimensionality and the limited range of the data values makes visualization of single nucleotide polymorphism (SNP) datasets challenging. The purpose of this study is to evaluate the usefulness of 3D VizStruct, a novel multi-dimensional dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675f33afe5073fb0aa87824b25892039
http://europepmc.org/articles/PMC1557808
http://europepmc.org/articles/PMC1557808
Publikováno v:
Bioinformatics; Jul2006, Vol. 22 Issue 13, p1569-1576, 8p