Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kavitha Anandalingam"'
Autor:
Ronald van den Berg, Kavitha Anandalingam, Ariel Zylberberg, Roozbeh Kiani, Michael N Shadlen, Daniel M Wolpert
Publikováno v:
eLife, Vol 5 (2016)
Decisions are accompanied by a degree of confidence that a selected option is correct. A sequential sampling framework explains the speed and accuracy of decisions and extends naturally to the confidence that the decision rendered is likely to be cor
Externí odkaz:
https://doaj.org/article/e7b8f780f7014b849812e4ee5410f8f6
Publikováno v:
Psychiatric News. 57
Autor:
Ariel Zylberberg, Daniel M. Wolpert, Roozbeh Kiani, Michael N. Shadlen, Kavitha Anandalingam, Ronald van den Berg
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
Decisions are accompanied by a degree of confidence that a selected option is correct. A sequential sampling framework explains the speed and accuracy of decisions and extends naturally to the confidence that the decision rendered is likely to be cor
Autor:
Lisa M. Ranzenhofer, Jack A. Yanovski, Kavitha Anandalingam, Marian Tanofsky-Kraff, Joan C. Han, Susan Z. Yanovski, Merel Kozlosky, Caroline A. Roza, Laura E. Wolkoff, Lauren B. Shomaker, Kelli M. Columbo, Camden Elliott
Publikováno v:
The American Journal of Clinical Nutrition. 90:1483-1488
Background: Children with rs9939609 FTO variant alleles (homozygous = AA and heterozygous = AT) are predisposed to greater adiposity than are those with 2 wild-type alleles (TT). Objective: Because FTO is highly expressed in hypothalamic regions that
Autor:
Cong Ning, Laura E. Wolkoff, Roberto E Figueroa, Rachael A Sorg, Caroline A. Roza, Marian Tanofsky-Kraff, Kavitha Anandalingam, Sheila M. Brady, Merel Kozlosky, Joan C. Han, Jack A. Yanovski, David M Savastano, Kyra S. Jefferson-George, Ethan L. Sanford, Dale A. Schoeller
Publikováno v:
The American Journal of Clinical Nutrition. 90:912-920
Background: Homozygosity for 2 protein-altering polymorphisms in the melanocortin-3 receptor gene (MC3R) coding sequence, C17A and G241A, has been reported to be associated with an obesity phenotype in children, yet how these polymorphisms affect ene
Autor:
Kavitha Anandalingam, Peter M. Glazer, Rachel J. Fields, Lee A. Polikoff, W. Mark Saltzman, Elias Quijano, Marie E. Egan, John P. Geibel, Anisha Gupta, Yong Kong, Raman Bahal, Nicole Ali McNeer, Sascha Kopic, Christina Caputo
Publikováno v:
Nature Communications. 6
Cystic fibrosis is a lethal genetic disorder commonly caused by the F508del mutation which is not amenable to gene therapy. Here, the authors use triplex-forming PNA molecules and donor DNA in biodegradable polymer nanoparticles to correct F508del an
Autor:
Nicole Ali McNeer, Peter M. Glazer, Kavitha Anandalingam, William Mark Saltzman, Adele S. Ricciardi
Publikováno v:
Methods in Molecular Biology ISBN: 9781493909919
Triplex-forming oligonucleotides (TFOs) are capable of coordinating genome modification in a targeted, site-specific manner, causing mutagenesis or even coordinating homologous recombination events. Here, we describe the use of TFOs such as peptide n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c7e8b3a19be6268deab69f2ebbdfd4
https://doi.org/10.1007/978-1-4939-0992-6_8
https://doi.org/10.1007/978-1-4939-0992-6_8
Autor:
Andrew Jackson, Dale L. Greiner, Leonard D. Shultz, Nicole Ali McNeer, Kavitha Anandalingam, Erica B. Schleifman, W. Mark Saltzman, Christopher J. Cheng, Peter M. Glazer, Priti Kumar, Amy Cuthbert, Michael A. Brehm
Publikováno v:
Gene therapy. 20(6)
In vivo delivery is a major barrier to the use of molecular tools for gene modification. Here we demonstrate site-specific gene editing of human cells in vivo in hematopoietic stem cell-engrafted NOD.Cg-Prkdc(scid)IL2rγ(tm1Wjl) (abbreviated NOD-scid