Výsledky vyhledávání - "Kavita Tundwal"

Functional T Cell Assays Are Predictive of Pre-Clinical Potency to Generate Allogeneic, Hypoimmune CD19 CAR T Cells

Autor: Darin Salloum, PhD, Kavita Tundwal, Divy Kangeyan, PhD, Adam Johnson, Neal van Hoeven, PhD, Brian Granger, Jesus Moreno, Ouwen Liang, Pascal Beauchesne, Terry J. Fry, Aaron Foster

Publikováno v: Blood. 140:4524-4525

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b45db414f8e0d96262a104d7c5e49a2e
https://doi.org/10.1182/blood-2022-168372

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Establishment of Extracellular Signal-Regulated Kinase 1/2 Bistability and Sustained Activation through Sprouty 2 and Its Relevance for Epithelial Function▿

Autor: Sally E. Wenzel, Weimin Liu, Silvana Balzar, Sadee Rozario, Kavita Tundwal, Rafeul Alam, Nayeem Quayum, Q. Liang, Magdalena M. Gorska, Nick P. Goplen

Our objective was to establish an experimental model of a self-sustained and bistable extracellular signal-regulated kinase 1/2 (ERK1/2) signaling process. A single stimulation of cells with cytokines causes rapid ERK1/2 activation, which returns to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36505c34d31d847e57dfab0b280a99b1
https://europepmc.org/articles/PMC2838067/

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MED220/thyroid receptor-associated protein 220 functions as a transcriptional coactivator with Pit-1 and GATA-2 on the thyrotropin-beta promoter in thyrotropes

Autor: E C Ridgway, David F. Gordon, Kavita Tundwal, William M. Wood, Heather Hall, Elizabeth A. Tucker

Publikováno v: Molecular endocrinology (Baltimore, Md.). 20(5)

Mediator (MED) 220/thyroid receptor-associated protein (TRAP) 220 is a transcriptional mediator that interacts with liganded thyroid/steroid hormone receptors. MED220 haploinsufficient heterozygotes exhibited hypothyroidism and reduced TSHβ transcri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c138a27c9d5b8825c5a8e1fa9a46a6d6
https://pubmed.ncbi.nlm.nih.gov/16396960

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JAK and Src tyrosine kinase signaling in asthma

Autor: Kavita Tundwal, Rafeul Alam

Publikováno v: Frontiers in Bioscience. 17:2107

Tyrosine kinases play a critical role in transducing intracellular signals from the receptors. Many receptors do not have intrinsic tyrosine kinase activity, so they rely on cytosolic and/or membrane-associated tyrosine kinases for initial signal gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba606f87f2f556d852d16ef642baa84e
https://doi.org/10.2741/4040

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