Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kavita Ramamoorthy"'
Autor:
Jeong-Eun Lee, Stephen Safe, Mona Sethi Gupta, Andrew McDougal, David A. Morrow, Kavita Ramamoorthy
Publikováno v:
Breast Cancer Research and Treatment. 66:147-157
Diindolylmethane (DIM) is formed by acid catalyzed dimerization of the phytochemical indole-3-carbinol, and both compounds inhibit formation and/or growth of mammary tumors in rodents. In this study, we have investigated the aryl hydrocarbon receptor
Publikováno v:
Molecular and Cellular Endocrinology. 162:211-220
Differences in ligand-activation of estrogen receptor alpha (ER(alpha)) were investigated in human HepG2 liver carcinoma and U2 osteogenic sarcoma cells transfected with wild-type ER (ER-wt) and variants expressing only activation function 1 (ERAF1)
Publikováno v:
Carcinogenesis. 20:115-123
3,3',4,4'-Tetrachlorobiphenyl (tetraCB) binds to the aryl hydrocarbon receptor (AhR), and several reports have demonstrated that AhR agonists exhibit antiestrogenic and antitumorigenic activities in human breast cancer cells, the rodent uterus and br
Autor:
Ichen Chen, C. Vyhlidal, Stephen Safe, Kevin W. Gaido, Fen Wang, Kavita Ramamoorthy, Linda S. Leonard, Donald P. McDonnell
Publikováno v:
Toxicology and Applied Pharmacology. 147:93-100
The estrogenic activity of 2',4',6'-trichloro-4-biphenylol (HO-PCB3), 2',3',4',5'-tetrachloro-4-biphenylol (HO-PCB4), and an equimolar mixture of both compounds (HO-PCB3/HO-PCB4) was investigated in the 21-day-old B6C3F1 mouse uterus, MCF-7 and MDA-M
Autor:
Kevin W. Gaido, Linda S. Leonard, John D. Norris, Stephen Safe, Ichen Chen, Kavita Ramamoorthy, Donald P. McDonnell, Wayne P. Bocchinfuso, Kenneth S. Korach, Fan Wang
Publikováno v:
Endocrinology. 138:1520-1527
The estrogenic activity of dieldrin, toxaphene, and an equimolar mixture of both compounds (dieldrin/toxaphene) was investigated in the 21-day-old B6C3F1 mouse uterus, MCF-7 human breast cancer cells, and in yeast-based reporter gene assays. Treatmen
Publikováno v:
Cancer letters. 151(2)
This study investigates the antiestrogenic/estrogenic and antitumorigenic activities of the following diindolylmethane (DIM) derivatives: 4,4′-dichloro-, 5,5′-dichloro-, 6,6′-dichloro-, 5,5′-dibromo-, 5,5′-difluoro- and 5,5′-dichloro-2,2
Autor:
B Blankvoort, Ichen Chen, Kevin W. Gaido, Fen Wang, Stephen Safe, L Dohme, Kavita Ramamoorthy
Publikováno v:
Environmental Health Perspectives 106 (1998) Suppl. 6
Environmental Health Perspectives, 106(Suppl. 6), 1347-1351
Environmental Health Perspectives
Environmental Health Perspectives, 106(Suppl. 6), 1347-1351
Environmental Health Perspectives
The human diet contains industrial-derived, endocrine-active chemicals and higher levels of naturally occurring compounds that modulate multiple endocrine pathways. Hazard and risk assessment of these mixtures is complicated by noadditive interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4135c8706c8906f46408dfd1f6dda720
https://research.wur.nl/en/publications/comparative-estrogenic-activity-of-wine-extracts-and-organochlori
https://research.wur.nl/en/publications/comparative-estrogenic-activity-of-wine-extracts-and-organochlori
Autor:
Bradley E. Gillesby, Ichen Chen, K. Connor, M. Mustain, Stephen Safe, M. Moore, Patrick Balaguer, A. Joyeux, Timothy R. Zacharewski, Kavita Ramamoorthy
Publikováno v:
Toxicology and applied pharmacology. 145(1)
The effects of structure on the estrogenicity and antiestrogenicity of hydroxylated polychlorinated biphenyls were investigated using the following estrogen-sensitive assays: competitive binding to the rat and mouse cytosolic estrogen receptor (ER);
Autor:
John D. Norris, Ichen Chen, Bridgette M. Collins, Diane M. Klotz, Kenneth S. Korach, Kevin W. Gaido, Fen Wang, Louis J. Guillette, Peter M. Vonier, Wayne P. Bocchinfuso, Donald P. McDonnell, Kavita Ramamoorthy, John A. McLachlan, Stephen Safe, Steven F. Arnold
Publikováno v:
Science. 275:405-406