Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Kavisha Arora"'
Autor:
Jean-Pierre Amoakon, Jesun Lee, Pramodha Liyanage, Kavisha Arora, Anja Karlstaedt, Goutham Mylavarapu, Raouf Amin, Anjaparavanda P. Naren.
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110703- (2024)
Summary: Cystic fibrosis (CF) is a genetic disease caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Despite reports of CFTR expression on endothelial cells, pulmonary vascular perturbations, and perfusion d
Externí odkaz:
https://doaj.org/article/6c9f9478621e48cbaaa119d0b4927401
Autor:
Yunjie Huang, Kavisha Arora, Kyu Shik Mun, Fanmuyi Yang, ChangSuk Moon, Sunitha Yarlagadda, Anil Jegga, Timothy Weaver, Anjaparavanda P. Naren
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract The molecular mechanism of Endoplasmic Reticulum-associated degradation (ERAD) of Cystic fibrosis transmembrane-conductance regulator (CFTR) is largely unknown. Particularly, it is unknown what ER luminal factor(s) are involved in ERAD. Here
Externí odkaz:
https://doaj.org/article/a9ead2c7e3d246a98726846c361c73db
Autor:
Kyu Shik Mun, Kavisha Arora, Yunjie Huang, Fanmuyi Yang, Sunitha Yarlagadda, Yashaswini Ramananda, Maisam Abu-El-Haija, Joseph J. Palermo, Balamurugan N. Appakalai, Jaimie D. Nathan, Anjaparavanda P. Naren
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Defective CFTR protein, responsible for Cystic Fibrosis (CF), is highly expressed in pancreatic ductal epithelial cells (PDECs) but their impact on insulin secreting pancreatic islets is not fully understood. Here the authors develop a non-CF and CF
Externí odkaz:
https://doaj.org/article/fc92be52f03349bab8a0daee67da4a27
Autor:
Jun Hyoung Park, Sajna Vithayathil, Santosh Kumar, Pi-Lin Sung, Lacey Elizabeth Dobrolecki, Vasanta Putluri, Vadiraja B. Bhat, Salil Kumar Bhowmik, Vineet Gupta, Kavisha Arora, Danli Wu, Efrosini Tsouko, Yiqun Zhang, Suman Maity, Taraka R. Donti, Brett H. Graham, Daniel E. Frigo, Cristian Coarfa, Patricia Yotnda, Nagireddy Putluri, Arun Sreekumar, Michael T. Lewis, Chad J. Creighton, Lee-Jun C. Wong, Benny Abraham Kaipparettu
Publikováno v:
Cell Reports, Vol 14, Iss 9, Pp 2154-2165 (2016)
Transmitochondrial cybrids and multiple OMICs approaches were used to understand mitochondrial reprogramming and mitochondria-regulated cancer pathways in triple-negative breast cancer (TNBC). Analysis of cybrids and established breast cancer (BC) ce
Externí odkaz:
https://doaj.org/article/28c753416ec244359418fa4cf4d08719
Autor:
Kavisha Arora, Nambirajan Sundaram, Yashaswini Ramananda, Michael Helmrath, Anjaparavanda P Naren
Publikováno v:
Physiology. 38
Background: Stem cell-derived organotypic culture has become a revolutionary tool in transforming care for patients with multiple GI-disorders. Cystic fibrosis is a deadly genetic disorder with multiple GI complications, such as Distal intestinal obs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19332e423efeee19a3c03dad0be148e1
https://doi.org/10.1152/physiol.2023.38.s1.5711443
https://doi.org/10.1152/physiol.2023.38.s1.5711443
Autor:
Anjaparavanda P. Naren, Alexander R. Cortez, Herbert Luke Ogden, Kavisha Arora, John J. Brewington, Fanmuyi Yang, John P. Clancy, Nambirajan Sundaram, Michael A. Helmrath, Yashaswini Ramananda, Gary L. McPhail
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Cystic fibrosis is a deadly multiorgan disorder caused by loss of function mutations in the gene that encodes for the cystic fibrosis transmembrane conductance regulator (CFTR) chloride/bicarbonate ion channel. More than 1,700 CFTR genetic variants e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8db53beb5386cb91d568dcc3e6030a
https://doi.org/10.1152/ajpgi.00095.2021
https://doi.org/10.1152/ajpgi.00095.2021
Autor:
Anjaparavanda P. Naren, Kavisha Arora
Publikováno v:
Reference Module in Biomedical Sciences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1441bd202556e6dc0892c5e1c13f9d6
https://doi.org/10.1016/b978-0-12-820472-6.00137-7
https://doi.org/10.1016/b978-0-12-820472-6.00137-7
Autor:
Changsuk Moon, Yunjie Huang, Sunitha Yarlagadda, Kyu Shik Mun, Kavisha Arora, Anil G. Jegga, Anjaparavanda P. Naren, Fanmuyi Yang, Timothy E. Weaver
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
The molecular mechanism of Endoplasmic Reticulum-associated degradation (ERAD) of Cystic fibrosis transmembrane-conductance regulator (CFTR) is largely unknown. Particularly, it is unknown what ER luminal factor(s) are involved in ERAD. Herein, we us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8801f52626c5e29792d8eae0730073b
https://doaj.org/article/a9ead2c7e3d246a98726846c361c73db
https://doaj.org/article/a9ead2c7e3d246a98726846c361c73db
Autor:
Amnah Yamani, Mark Rochman, Philip E. Putnam, Marc E. Rothenberg, Kavisha Arora, John A. Besse, Vincent A. Mukkada, Taeko K. Noah, Mirna Chehade, David Wu, Simone Vanoni, Julie M. Caldwell, Ting Wen, Chang Zeng, Simon P. Hogan, Margaret H. Collins, Lisa Waggoner, Justin C. Wheeler, Jazib Uddin, Anjaparavanda P. Naren
Publikováno v:
J Allergy Clin Immunol
Background Eosinophilic esophagitis (EoE) is characterized by histopathologic modifications of esophageal tissue, including eosinophil-rich inflammation, basal zone hyperplasia, and dilated intercellular spaces (DIS). The underlying molecular process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10fb425fe100da3e94cdbae794681a48
https://doi.org/10.1016/j.jaci.2018.03.017
https://doi.org/10.1016/j.jaci.2018.03.017
Publikováno v:
Gastroenterology. 162:S-704
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca4f699c75a55ce52dbe2871ba1c4fb8
https://doi.org/10.1016/s0016-5085(22)61650-0
https://doi.org/10.1016/s0016-5085(22)61650-0