Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kaveesha, Bodiyabadu"'
Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium
Autor:
Duygu Durukan, Michelle Doyle, Gerald Murray, Kaveesha Bodiyabadu, Lenka Vodstrcil, Eric P.F. Chow, Jorgen S. Jensen, Christopher K. Fairley, Ivette Aguirre, Catriona S. Bradshaw
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 8, Pp 1870-1874 (2020)
Antimicrobial-resistant Mycoplasma genitalium is becoming increasingly common and creating major treatment challenges. We present early data on combination therapy with doxycycline and sitafloxacin to treat highly resistant M. genitalium. We found th
Externí odkaz:
https://doaj.org/article/faba4b9a41a94648ba5acd66a2d800cc
Autor:
Cheng Rui Peh, Jennifer Danielewski, Teck Phui Chua, Kaveesha Bodiyabadu, Dorothy A Machalek, Suzanne M Garland, Catriona S Bradshaw, Gerald L Murray
Publikováno v:
Letters in Applied Microbiology.
Mycoplasma genitalium is a sexually transmitted infection with increasing concerns around antimicrobial resistance. Droplet digital PCR (ddPCR) is rapid quantification method with high precision that may be useful for absolute quantitation of bacteri
Autor:
Gerald L Murray, Erica L Plummer, Kaveesha Bodiyabadu, Lenka A Vodstrcil, Jose L Huaman, Jennifer A Danielewski, Teck Phui Chua, Dorothy A Machalek, Suzanne Garland, Michelle Doyle, Emma L Sweeney, David M Whiley, Catriona S Bradshaw
Publikováno v:
Clinical Infectious Diseases.
BackgroundAlthough single nucleotide polymorphisms (SNPs) in Mycoplasma genitalium parC contribute to fluoroquinolone treatment failure, data are limited for the homologous gene, gyrA. This study investigated the prevalence of gyrA SNPs and their con
Autor:
Lenka A Vodstrcil, Erica L Plummer, Michelle Doyle, Gerald L Murray, Kaveesha Bodiyabadu, Jorgen S Jensen, David Whiley, Emma Sweeney, Deborah A Williamson, Eric P F Chow, Christopher K Fairley, Catriona S Bradshaw
Publikováno v:
Clinical Infectious Diseases. 75:813-823
Background Mycoplasma genitalium (MG) infection is challenging to cure because of rising antimicrobial resistance and limited treatment options. Methods This was a prospective evaluation of the efficacy and tolerability of resistance-guided combinati
Autor:
Gerald L. Murray, Kaveesha Bodiyabadu, Lenka A. Vodstrcil, Dorothy A. Machalek, Jennifer Danielewski, Erica L. Plummer, Suzanne M. Garland, David M. Whiley, Emma L. Sweeney, Catriona S. Bradshaw
Publikováno v:
Antimicrob Agents Chemother
Prevalence, trends, and treatment outcome estimates were generated for parC variants in macrolide-resistant Mycoplasma genitalium. Among 539 cases, the most common amino acid change was S83I, which increased from 13% in 2012 to 2013, to 23% in 2019 t
Autor:
Rosie L. Latimer, Michelle Doyle, Eric P F Chow, Catriona S. Bradshaw, Christopher K Fairley, Erica L Plummer, Kaveesha Bodiyabadu, Matthew S. Payne, Suzanne M. Garland, Lenka A. Vodstrcil, Gerald L. Murray
Publikováno v:
Clinical Infectious Diseases. 73:659-668
Background There is limited evidence supporting an association between Mycoplasma hominis, Ureaplasma urealyticum, and Ureaplasma parvum with symptoms or disease in nonpregnant women. However, testing and reporting of these organisms frequently occur
Autor:
Teck-Phui Chua, Jennifer Danielewski, Kaveesha Bodiyabadu, Catriona S. Bradshaw, Dorothy A. Machalek, Suzanne M. Garland, Erica L. Plummer, Lenka A. Vodstrcil, Gerald L. Murray
Publikováno v:
Antimicrob Agents Chemother
Doxycycline targets the 16S rRNA and is widely used for the treatment of sexually transmitted infections. While it is not highly effective at eradicating Mycoplasma genitalium infections, it can reduce organism load. The aim of this study was to inve
Autor:
Gerald L. Murray, Suzanne M. Garland, Michelle L Doyle, Dorothy A Machalek, Lenka A. Vodstrcil, Teck-Phui Chua, Jennifer Danielewski, Catriona S. Bradshaw, Erica L Plummer, Kaveesha Bodiyabadu
Publikováno v:
Journal of Medical Microbiology
Introduction. Failure of fluoroquinolones, the principal treatment option for macrolide-resistant Mycoplasma genitalium infections, has recently emerged. This is of particular concern for men who have sex with men (MSM), who have high proportions of
Autor:
Marie Lundgren, Suzanne M. Garland, Gerald L. Murray, Catriona S. Bradshaw, Samantha Ebeyan, Jennifer Danielewski, Kaveesha Bodiyabadu, Joshua Birnie, Dorothy A Machalek
Publikováno v:
Journal of Medical Microbiology. 70
Introduction. Increasing levels of antibiotic resistance are complicating treatment for the sexually transmitted pathogen Mycoplasma genitalium . Resistance to fluoroquinolones is associated with mutations in the parC gene. Although the precise mutat
Autor:
Kaveesha, Bodiyabadu, Jennifer, Danielewski, Suzanne M, Garland, Dorothy A, Machalek, Catriona S, Bradshaw, Joshua, Birnie, Samantha, Ebeyan, Marie, Lundgren, Gerald, Murray
Publikováno v:
Journal of Medical Microbiology
Introduction Increasing levels of antibiotic resistance are complicating treatment for the sexually transmitted pathogen Mycoplasma genitalium . Resistance to fluoroquinolones is associated with mutations in the parC gene. Although the precise mutati