Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kavan H, Hess"'
Autor:
Talon J. Aitken, Jeffery S. Tessem, Brennan R. Leininger, Kavan H. Hess, Jacqueline E. Crabtree, Daelin M. Jensen
Publikováno v:
Biology of the Cell. 113:507-521
BACKGROUND Over 400 million people are diabetic. Type 1 and type 2 diabetes are characterized by decreased functional β-cell mass and, consequently, decreased glucose-stimulated insulin secretion. A potential intervention is transplantation of β-ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cce43fe00e30f7130a9f57b345ad759c
https://doi.org/10.1111/boc.202100035
https://doi.org/10.1111/boc.202100035
Autor:
Talon J, Aitken, Jacqueline E, Crabtree, Daelin M, Jensen, Kavan H, Hess, Brennan R, Leininger, Jeffery S, Tessem
Publikováno v:
Biol Cell
BACKGROUND: Over 400 million people are diabetic. Type 1 and type 2 diabetes are characterized by decreased functional β-cell mass and, consequently, decreased glucose-stimulated insulin secretion. A potential intervention is transplantation of β-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8b5946e53fa999b6a33a844f5f44efc1
https://pubmed.ncbi.nlm.nih.gov/34523154
https://pubmed.ncbi.nlm.nih.gov/34523154
Autor:
Jacob Herring, Jeffery S. Tessem, Yann Deleye, Robert W. McGarrah, Brennan Leininger, Phillip J. White, Kavan H. Hess
Publikováno v:
Diabetes. 70
Phosphorylation of ribosomal protein S6 (RPS6) on ser235/236 and ser240/244 in the pancreatic beta cell increases cell size and insulin content and influences systemic glucose homeostasis. Our phosphoproteomic analysis identified the protein phosphat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbfb34cfeb3cfeae2fe0332be94b97af
https://doi.org/10.2337/db21-1244-p
https://doi.org/10.2337/db21-1244-p
Autor:
Brennan Leininger, Phillip J. White, Jeffery S. Tessem, Robert W. McGarrah, Kavan H. Hess, Yann Deleye, Jacob Herring
Publikováno v:
Diabetes. 69
The protein phosphatase m1K (PPm1K) dephosphorylates and activates the rate limiting enzyme in the branched-chain amino acid (BCAA) catabolism pathway, branched chain a-keto acid dehydrogenase (BCKDH). A common single nucleotide polymorphism upstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c78c20b897087b0110fc9a47c5260f4
https://doi.org/10.2337/db20-2120-p
https://doi.org/10.2337/db20-2120-p
Autor:
Kavan H. Hess, Inna Astapova, Jeffery S. Tessem, Brennan Leininger, Sarah A. Hannou, Jacob Herring, Phillip J. White, Mark A. Herman, Yann Deleye
Publikováno v:
Diabetes. 68
A single nucleotide polymorphism in the gene encoding the protein phosphatase m1K (PPm1K) is associated with increased risk for the development of type 2 diabetes but not insulin resistance in humans. We recently discovered that expression of the PPM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb0b293fbe83845217e7b8804947c4d4
https://doi.org/10.2337/db19-2191-p
https://doi.org/10.2337/db19-2191-p
Autor:
Kyle B. Kener, Aaron H. Leifer, Amanda Haines, Jeffery S. Tessem, Courtney J. Smith, Patrick T. Fueger, Kavan H. Hess, Angelina Hernandez-Carretero, Michelle Arlotto, Lanair A. Lett, Carrie Draney, Matthew C. Austin, Talon J. Aitken
Publikováno v:
The Biochemical journal. 475(24)
The homeobox transcription factor Nkx6.1 is sufficient to increase functional β-cell mass, where functional β-cell mass refers to the combination of β-cell proliferation, glucose-stimulated insulin secretion (GSIS) and β-cell survival. Here, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82da34a1daca34183a96d4b0f1623c5
https://pubmed.ncbi.nlm.nih.gov/30322885
https://pubmed.ncbi.nlm.nih.gov/30322885