Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kaushik P. Sharma"'
Publikováno v:
IET Image Processing, Vol 15, Iss 3, Pp 735-745 (2021)
Abstract This paper presents an approach to segment lesions from brain magnetic resonance images in a fully automatic manner. The proposed idea leverages the strength of classical random walker algorithm and graph cut optimization technique in a sing
Externí odkaz:
https://doaj.org/article/92244de4245949eeb3b6213ca26af29a
Publikováno v:
Sensors & Transducers, Vol 209, Iss 2, Pp 45-49 (2017)
In this paper identification of a faulty load bus has been done in a multi-bus power system for double line fault, monitoring the feeder operating points and load angles in presence of various frequencies in harmonic P-d plane. The usage of a new adv
Externí odkaz:
https://doaj.org/article/cfbd0380b6ab446284874420a1acfbb5
Publikováno v:
Neurobiology of Stress, Vol 9, Iss, Pp 9-21 (2018)
Neurobiology of Stress
Neurobiology of Stress
Microglia are the predominant immune cells of the central nervous system (CNS) that exert key physiological roles required for maintaining CNS homeostasis, notably in response to chronic stress, as well as mediating synaptic plasticity, learning and
Akademický článek
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Autor:
Li Tian, Song Chen, Yunlong Tan, Marie-Ève Tremblay, Xiang Yang Zhang, Kaushik P. Sharma, Chin Wai Hui, Kanchan Bisht
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 79:27-39
Mounting evidence indicates the importance of microglia for proper brain development and function, as well as in complex stress-related neuropsychiatric disorders and cognitive decline along the aging trajectory. Considering that microglia are reside
Publikováno v:
Communicative & Integrative Biology
Communicative & Integrative Biology, Vol 9, Iss 6 (2016)
Communicative & Integrative Biology, Vol 9, Iss 6 (2016)
Using transmission electron microscopy (TEM) we recently characterized a microglial phenotype that is induced by chronic stress, fractalkine receptor deficiency, aging, or Alzheimer disease pathology. These ‘dark’ microglia appear overly active c
Autor:
Luc Vallières, Diego Gomez-Nicola, Oleg Butovsky, Cynthia Lecours, Kaushik P. Sharma, Adrian Olmos-Alonso, Maria Gabriela Sánchez, Giampaolo Milior, Kanchan Bisht, Hassan El Hajj, Laura Maggi, Igor Branchi, Marie-Ève Tremblay, Cristina Limatola, Giamal N. Luheshi
Publikováno v:
Glia
The past decade has witnessed a revolution in our understanding of microglia. These immune cells were shown to actively remodel neuronal circuits, leading to propose new pathogenic mechanisms. To study microglial implication in the loss of synapses,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0938075231a738fd94c10bb9b1b8c009
http://hdl.handle.net/11573/854985
http://hdl.handle.net/11573/854985
Publikováno v:
Neuroscience. 167:354-360
Phosphorylation is critically involved in synaptic plasticity and memory. Recent studies have shown that another posttranslational modification, acetylation, particularly of histone H3, also plays important roles in long-term potentiation and memory.
Publikováno v:
Learningmemory (Cold Spring Harbor, N.Y.). 22(10)
Massed training is less effective for long-term memory formation than the spaced training. The role of acetylation in synaptic plasticity and memory is now well established. However, the role of this important protein modification in synaptic plastic
Publikováno v:
Neuroreport. 25(7)
Protein phosphorylation is known to regulate synaptic plasticity and memory. Protein kinases including protein kinase A and extracellular signal-regulated kinase (ERK) play important roles in these processes. Forskolin, a protein kinase A activator,