Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kaushik Gurunathan"'
Publikováno v:
Current Biology. 24(13):1437-1446
Summary Background The kinetochore is a multiprotein machine that couples chromosome movement to microtubule (MT) polymerization and depolymerization. It uses numerous copies of at least three MT-binding proteins to generate bidirectional movement. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ede30d3af7d8555f8d15099212f17c4
Publikováno v:
Journal of Molecular Biology. 411:430-448
Nucleosomes sterically occlude their wrapped DNA from interacting with many large protein complexes. How proteins gain access to nucleosomal DNA target sites in vivo is not known. Outer stretches of nucleosomal DNA spontaneously unwrap and rewrap wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11d397b0b258111745c05a23bd7e801
https://doi.org/10.1016/j.jmb.2011.05.044
https://doi.org/10.1016/j.jmb.2011.05.044
Autor:
Marcia Levitus, Kaushik Gurunathan
Publikováno v:
Current Pharmaceutical Biotechnology. 10:558-567
Single-molecule techniques have transformed dramatically the way we think about biophysics, making it possible to address questions about the dynamics of systems in equilibrium that were practically unthinkable just a decade ago. This review focuses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c390a25db2ec14949a07b0a5c10ba5c8
https://doi.org/10.2174/138920109788922074
https://doi.org/10.2174/138920109788922074
Autor:
Marcia Levitus, Kaushik Gurunathan
Publikováno v:
Biophysical Journal. 98(3)
Nucleosomes are the fundamental repeating unit of eukaryotic chromatin. Often large protein complexes encounter a hurdle when their target DNA sites are sterically occluded inside these nucleosomes. One of the models by which DNA sites are exposed is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca277d2cc9d06881a4c29d2807ddd23
Autor:
Kaushik Gurunathan, Marcia Levitus
Publikováno v:
The journal of physical chemistry. B. 114(2)
The use of fluorescence correlation spectroscopy (FCS) to study conformational dynamics in diffusing biopolymers requires that the contributions to the signal due to translational diffusion are separated from those due to conformational dynamics. A s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b73718a817d76057b9dd9342184f68
https://pubmed.ncbi.nlm.nih.gov/20030305
https://pubmed.ncbi.nlm.nih.gov/20030305
Publikováno v:
The journal of physical chemistry. B. 113(22)
We have investigated the photophysical properties of backbone fluorescent DNA modifications with the goal of reducing many of the sources of uncertainty commonly encountered in Forster resonance energy transfer (FRET) measurements. We show that backb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4b8185764cc2759eaa08b5f9db251c
https://pubmed.ncbi.nlm.nih.gov/19473039
https://pubmed.ncbi.nlm.nih.gov/19473039
Autor:
Kaushik, Gurunathan, Marcia, Levitus
Publikováno v:
Progress in nucleic acid research and molecular biology. 82
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9182ac77ddb6bd1576cdfde631054c2
https://pubmed.ncbi.nlm.nih.gov/18929138
https://pubmed.ncbi.nlm.nih.gov/18929138
Publikováno v:
The journal of physical chemistry. B. 111(37)
The sulfoindocyanine Cy3 is one of the most commonly used fluorescent dyes in the investigation of the structure and dynamics of nucleic acids by means of fluorescence methods. In this work, we report the fluorescence and photophysical properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5e335abd8788ff37a523f710e71924
https://pubmed.ncbi.nlm.nih.gov/17718469
https://pubmed.ncbi.nlm.nih.gov/17718469
Autor:
Kaushik Gurunathan, Marcia Levitus
Publikováno v:
Journal of Physical Chemistry B; Jan2010, Vol. 114 Issue 2, p980-986, 7p
Publikováno v:
Journal of Physical Chemistry B; Jun2009, Vol. 113 Issue 22, p7861-7866, 6p