Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Kaushik Chakrabarty"'
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Akademický článek
Bacillus anthracis peptidoglycan stimulates an inflammatory response in monocytes through the p38 mitogen-activated protein kinase pathway.
Autor: Marybeth Langer, Alexander Malykhin, Kenichiro Maeda, Kaushik Chakrabarty, Kelly S Williamson, Christa L Feasley, Christopher M West, Jordan P Metcalf, K Mark Coggeshall
Publikováno v: PLoS ONE, Vol 3, Iss 11, p e3706 (2008)
We hypothesized that the peptidoglycan component of B. anthracis may play a critical role in morbidity and mortality associated with inhalation anthrax. To explore this issue, we purified the peptidoglycan component of the bacterial cell wall and stu
Externí odkaz: https://doaj.org/article/7f65f2d302e44a71a511eff8c7ae6fa9
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4
Resistance of Human Alveolar Macrophages toBacillus anthracisLethal Toxin
Autor: K. Mark Coggeshall, Jordan P. Metcalf, J. Leland Booth, Krupa B. Patel, Harshini Mehta, Jimmy D. Ballard, Elizabeth S. Duggan, Wenxin Wu, Kaushik Chakrabarty
Publikováno v: The Journal of Immunology. 183:5799-5806
The etiologic agent of inhalational anthrax, Bacillus anthracis, produces virulence toxins that are important in the disease pathogenesis. Current studies suggest that mouse and human macrophages are susceptible to immunosuppressive effects of one of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::843bb078c37b00e039cefb22c12747e7
https://doi.org/10.4049/jimmunol.0803406
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5
Human Lung Innate Immune Response toBacillus anthracisSpore Infection
Autor: Nancy N. Nagle, Elizabeth S. Duggan, K. Mark Coggeshall, J. Leland Booth, Wenxin Wu, Jordan P. Metcalf, Kaushik Chakrabarty
Publikováno v: Infection and Immunity. 75:3729-3738
Bacillus anthracis, the causative agent of inhalational anthrax, enters a host through the pulmonary system before dissemination. We have previously shown that human alveolar macrophages participate in the initial innate immune response toB. anthraci
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b08e724b916d4bbb27a8c0b8fe4aca
https://doi.org/10.1128/iai.00046-07
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6
Sufficient Progesterone-Priming Prior to Estradiol Stimulation Is Required for Optimal Induction of the Cervical Prostaglandin System in Pregnant Sheep at 0.7 Gestations1
Autor: Turhan Coksaygan, Wen Xuan Wu, Valta Collins, Peter W. Nathanielsz, Kaushik Chakrabarty, James C. Rose
Publikováno v: Biology of Reproduction. 73:343-350
The purposes of this study were to determine the separate and interactive functions of progesterone and estradiol in regulating the cervical prostaglandin (PG) system in pregnant sheep at 0.7 gestations. At 106–108 days of gestational age (dGA), ew
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f5e17d4d53191a1394e7cb37244c13a0
https://doi.org/10.1095/biolreprod.104.037820
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7
Glutamatergic Dysfunction in OCD
Autor: Sagnik Bhattacharyya, Sumant Khanna, Kaushik Chakrabarty, Rita Christopher
Publikováno v: Neuropsychopharmacology. 30:1735-1740
The role of glutamatergic dysfunction in the pathophysiology of OCD has hardly been explored despite recent reports implicating glutamatergic dysfunction in OCD. We decided to investigate CSF glutamate levels in adult OCD probands compared to psychia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827dddebf0dc0c47a5612d327b304679
https://doi.org/10.1038/sj.npp.1300733
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8
Quality-control analytical methods: endotoxins: essential testing for pyrogens in the compounding laboratory, part2
Autor: James F, Cooper, Kaushik, Chakrabarty, Jason, McGuire, William J, Zolner, Vann, Jones, Hilary, Hedman
Publikováno v: International journal of pharmaceutical compounding. 14(6)
Ensuring that the endotoxin burden in sterile preparations is within allowable limits is one of the greatest challenges faced by compounding pharmacists. Today, endotoxin analyses can be performed in the pharmacy with a test kit or accomplished by se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cb9f5f5a840cf3429acf1c2172758410
https://pubmed.ncbi.nlm.nih.gov/23965654
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9
Gene expression profiling of human alveolar macrophages infected by B. anthracisspores demonstrates TNF-α and NF-κb are key components of the innate immune response to the pathogen
Autor: Robert E. Hurst, Kaushik Chakrabarty, Wenxin Wu, J. Leland Booth, Jordan P. Metcalf, Mikhail G. Dozmorov, K. Mark Coggeshall
Publikováno v: BMC Infectious Diseases, Vol 9, Iss 1, p 152 (2009)
BMC Infectious Diseases
Background Bacillus anthracis, the etiologic agent of anthrax, has recently been used as an agent of bioterrorism. The innate immune system initially appears to contain the pathogen at the site of entry. Because the human alveolar macrophage (HAM) pl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b56e19497584908981782fab65e2106
https://doi.org/10.1186/1471-2334-9-152
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