Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kaushalya Amunugama"'
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Dysregulated lipid metabolism is common in infection and inflammation and is a part of the complex milieu underlying the pathophysiological sequelae of disease. Sepsis is a major cause of mortality and morbidity in the world and is characterized by a
Externí odkaz:
https://doaj.org/article/6e659c60fbea40dcb0b6342f62b88d46
Autor:
Kaushalya Amunugama, Matthew J. Jellinek, Megan P. Kilroy, Carolyn J. Albert, Valerio Rasi, Daniel F. Hoft, Michael G.S. Shashaty, Nuala J. Meyer, David A. Ford
Publikováno v:
Redox Biology, Vol 48, Iss , Pp 102208- (2021)
Plasmalogens are a class of phospholipids containing vinyl ether linked aliphatic groups at the sn-1 position. Plasmalogens are known to contain 16- and 18-carbon aliphatic groups at the sn-1 position. Here, we reveal that the human neutrophil plasme
Externí odkaz:
https://doaj.org/article/b5609e828bfd466eab64b90bcfed7e70
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophils are the most abundant white blood cells recruited to the sites of infection and inflammation. During neutrophil activation, myeloperoxidase (MPO) is released and converts hydrogen peroxide to hypochlorous acid (HOCl). HOCl reacts with pla
Externí odkaz:
https://doaj.org/article/d92852cb9c86460ca5bf613d09b48886
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100090- (2021)
Sepsis, defined as the dysregulated immune response to an infection leading to organ dysfunction, is one of the leading causes of mortality around the globe. Despite the significant progress in delineating the underlying mechanisms of sepsis pathogen
Externí odkaz:
https://doaj.org/article/08bc3eb2497f40df8f87026e8511b99f
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100090-(2021)
Journal of Lipid Research
Journal of Lipid Research
Sepsis, defined as the dysregulated immune response to an infection leading to organ dysfunction, is one of the leading causes of mortality around the globe. Despite the significant progress in delineating the underlying mechanisms of sepsis pathogen
Autor:
David A. Ford, Kaushalya Amunugama
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Kaushalya Amunugama, Chen Hou
Publikováno v:
Mechanisms of Ageing and Development. 149:50-64
The relationship between energy expenditure and longevity has been a central theme in aging studies. Empirical studies have yielded controversial results, which cannot be reconciled by existing theories. In this paper, we present a simple theoretical
Autor:
Chen Hou, Yue-Wern Huang, Paul Ki-souk Nam, Lihong Jiao, Chance Walker, Kaushalya Amunugama, Gayla R. Olbricht
Publikováno v:
Experimental gerontology. 82
We develop a theoretical model from an energetic viewpoint for unraveling the entangled effects of metabolic and biosynthetic rates on oxidative cellular damage accumulation during animal's growth, and test the model by experiments in hornworms. The
Autor:
Azriel Domingo, Lihong Jiao, Michael Jennings, Chen Hou, Matthew B. Hayes, Kaushalya Amunugama
Publikováno v:
The Science of Nature. 102
Growing animals must alter their energy budget in the face of environmental changes and prioritize the energy allocation to metabolism for life-sustaining requirements and energy deposition in new biomass growth. We hypothesize that when food availab