Výsledky vyhledávání - "Kausar N. Samli"

Isolation of multiple cell-binding ligands from different phage displayed-peptide libraries

Autor: Irene T. Rombel, Tsukasa Oyama, Kathlynn C. Brown, Xin Zhou, Kausar N. Samli

Publikováno v: Biosensors and Bioelectronics. 21:1867-1875

A technical challenge in the development of biosensor devices for cancer detection and diagnosis is the identification of ligands that recognize cancer cells with high affinity and specificity. Furthermore, it is unlikely that one cell-binding ligand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8754ab1d585ba7b781ecb10b60f0bff
https://doi.org/10.1016/j.bios.2005.11.016

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Novel ligands for cancer diagnosis: Selection of peptide ligands for identification and isolation of B-cell lymphomas

Autor: Kathlynn C. Brown, Ya-Ching Chang, Kausar N. Samli, Michael J. McGuire

Publikováno v: Experimental Hematology. 34:443-452

Objective Lymphoma and leukemia account for nearly 8% of cancer fatalities each year. Present treatments do not differentiate between normal and malignant cells. New reagents that distinguish malignant cells and enable the isolation of these cells fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e56c61e6961dc163a4729e0f1fbc330
https://doi.org/10.1016/j.exphem.2005.12.013

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A peptide selected by biopanning identifies the integrin alphavbeta6 as a prognostic biomarker for nonsmall cell lung cancer

Autor: Ludmila Prudkin, Ying Horng Liu, Ignacio I. Wistuba, Aihua Bian, Kathlynn C. Brown, Anissa N. Elayadi, Michael J. McGuire, Xian Jin Xie, Kausar N. Samli, Jack A. Roth

Publikováno v: Cancer research. 67(12)

The development of new modes of diagnosis and targeted therapy for lung cancer is dependent on the identification of unique cell surface features on cancer cells and isolation of reagents that bind with high affinity and specificity to these biomarke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641d774ed0daf013c24ba334a3bb7b01
https://pubmed.ncbi.nlm.nih.gov/17575158

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Isolation of a mycoplasma-specific binding peptide from an unbiased phage-displayed peptide library

Autor: Christopher B. Newgard, Stephen Albert Johnston, Kathlynn C. Brown, Jonathan C. Schisler, Kausar N. Samli, Ya Ching Chang, Jitakshi De

Publikováno v: Molecular bioSystems. 1(2)

An important goal in medicine is the development of methods for cell-specific targeting of therapeutic molecules to pathogens or pathogen-infected cells. However, little progress has been made in cell-specific targeting of bacterially infected cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e12bf92f18652d766019dfe27b1d13b
https://pubmed.ncbi.nlm.nih.gov/16880978

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Peptide-mediated targeting of the islets of Langerhans

Autor: Michael J. McGuire, Kausar N. Samli, Christopher B. Newgard, Kathlynn C. Brown, Stephen Albert Johnston

Publikováno v: Diabetes. 54(7)

Strategies for restoring β-cell function in diabetic patients would be greatly aided by the ability to target genes, proteins, or small molecules specifically to these cells. Furthermore, the ability to direct imaging agents specifically to β-cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4153f3dd94793c346c984602fdbd5f03
https://pubmed.ncbi.nlm.nih.gov/15983211

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