Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kausalia Vijayaragavan"'
Autor:
Yunhao Bai, Bokai Zhu, John-Paul Oliveria, Bryan J. Cannon, Dorien Feyaerts, Marc Bosse, Kausalia Vijayaragavan, Noah F. Greenwald, Darci Phillips, Christian M. Schürch, Samuel M. Naik, Edward A. Ganio, Brice Gaudilliere, Scott J. Rodig, Michael B. Miller, Michael Angelo, Sean C. Bendall, Xavier Rovira-Clavé, Garry P. Nolan, Sizun Jiang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Cellular organization and functions encompass multiple scales in vivo. Emerging high-plex imaging technologies are limited in resolving subcellular biomolecular features. Expansion Microscopy (ExM) and related techniques physically expand sa
Externí odkaz:
https://doaj.org/article/1aaa853ff55a4176b7b32d00970f18f6
Autor:
Kausalia Vijayaragavan, Bryan J. Cannon, Dmitry Tebaykin, Marc Bossé, Alex Baranski, J. P. Oliveria, Syed A. Bukhari, Dunja Mrdjen, M. Ryan Corces, Erin F. McCaffrey, Noah F. Greenwald, Yari Sigal, Diana Marquez, Zumana Khair, Trevor Bruce, Mako Goldston, Anusha Bharadwaj, Kathleen S. Montine, R. Michael Angelo, Thomas J. Montine, Sean C. Bendall
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-22 (2022)
Abstract Neurodegenerative disorders are characterized by phenotypic changes and hallmark proteopathies. Quantifying these in archival human brain tissues remains indispensable for validating animal models and understanding disease mechanisms. We pre
Externí odkaz:
https://doaj.org/article/634355137dcd41ebab2eb6ab532fbf74
Autor:
Erin Soon, Tyler Risom, Noah F. Greenwald, Dunja Mrdjen, Kausalia Vijayaragavan, Erin McCaffrey, Sean C. Bendall, Michael Angelo, John-Paul Oliveria, Candace C. Liu, Dmitry Tebaykin, Marc Bosse
Publikováno v:
Annual Review of Pathology: Mechanisms of Disease. 17:403-423
Next-generation tools for multiplexed imaging have driven a new wave of innovation in understanding how single-cell function and tissue structure are interrelated. In previous work, we developed multiplexed ion beam imaging by time of flight, a highl
Autor:
Suzanne Craft, Ramin Fallahzadeh, Kausalia Vijayaragavan, Christopher Dirk Keene, Thomas C. Register, Kathleen L. Poston, Caitlin S. Latimer, Carol A. Shively, Thanaphong Phongpreecha, Nima Aghaeepour, Emily Sherfield, Kathleen S. Montine, Michael Angelo, Dmitry Tebaykin, Rosemary Fernandez, Nadia Postupna, Thomas J. Montine, Candace C. Liu, Chandresh R. Gajera, Alan L. Chang, Martin Becker, Edward J Fox, Sean C. Bendall
Publikováno v:
Science Advances
Description
Multiplex single-synapse events from multiple regions of Alzheimer’s disease brain revealed new alterations unique to humans.
Synaptic molecular characterization is limited for Alzheimer’s disease (AD). Our newly invented ma
Multiplex single-synapse events from multiple regions of Alzheimer’s disease brain revealed new alterations unique to humans.
Synaptic molecular characterization is limited for Alzheimer’s disease (AD). Our newly invented ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e81dff204c1da72d9755ec0df3ce95
https://doi.org/10.1101/2021.06.14.448240
https://doi.org/10.1101/2021.06.14.448240
Autor:
Samuel C. Kimmey, Marc Bosse, Joan Domingo-Reinés, Kara L. Davis, Sean C. Bendall, Verónica Ramos-Mejía, Kausalia Vijayaragavan
Publikováno v:
Cancer Research. 80:B29-B29
Pediatric acute myeloid leukemia (AML) is a rare disease characterized by an accumulation of immature white blood cells in the bone marrow and/or peripheral blood. In some cases, it is thought that the predisposition to leukemia begins in utero. Ofte
Autor:
Dmitry Tebaykin, Kausalia Vijayaragavan, Thomas J. Montine, Marc Bosse, Michael Angelo, Sean C. Bendall, John-Paul Oliveria
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
Jonathan S. Draper, James Ellis, Mickie Bhatia, Peter Pasceri, Cheryle A. Séguin, Kausalia Vijayaragavan, Akitsu Hotta, Natalie Farra, Janet Rossant, Dixie L. Mager, Aaron Y. L. Cheung, Irina A. Maksakova
Publikováno v:
Nature Methods. 6:370-376
Induced pluripotent stem (iPS) cells may be of use in regenerative medicine. However, the low efficiency of reprogramming is a major impediment to the generation of patient-specific iPS cell lines. Here we report the first selection system for the is
Autor:
Eva Szabo, Mickie Bhatia, Kausalia Vijayaragavan, Randall T. Moon, Marc Bossé, Verónica Ramos-Mejía
Publikováno v:
Cell Stem Cell. 4(3):248-262
SummaryDuring human development, signals that govern lineage specification versus expansion of cells committed to a cell fate are poorly understood. We demonstrate that activation of canonical Wnt signaling by Wnt3a promotes proliferation of human em
Publikováno v:
Trends in Pharmacological Sciences. 26:496-502
Voltage-gated Na(+) channels have an essential role in the biophysical properties of nociceptive neurons. Factors that regulate Na(+) channel function are of interest from both pathophysiological and therapeutic perspectives. Increasing evidence indi
Publikováno v:
British Journal of Pharmacology. 142:576-584
1 Voltage-gated Na+ channels are transmembrane proteins that are essential for the propagation of action potentials in excitable cells. Nav1.7 and Nav1.8 dorsal root ganglion Na+ channels exhibit different kinetics and sensitivities to tetrodotoxin (