Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kau-Ming Chen"'
Publikováno v:
Journal of the Chinese Chemical Society. 61:778-784
Camptothecin (CPT), a quinoline alkaloid, was found to possess anti-tumor activity. Two semi-synthetic derivatives of CPT, irinotecan and topotecan, have lower cytotoxicity and higher water solubility than that of CPT, were found effective for the tr
Autor:
Kau-Ming Chen, Mahavir Prashad, Oljan Repic, Carmine Villa, Kapa Prasad, Lech Ciszewski, George T. Lee, John C. Amedio
Publikováno v:
Organic Process Research & Development. 6:773-776
An efficient, safe, and cost-effective synthesis of 3-carboxy-(2R)-[[hydroxy[(tetradecyl)oxy]phosphinyl]oxy]-N,N,N-trimethyl-1-propanaminium hydroxide inner salt (1, CPI975), a carnitine palmitoyltransferase I inhibitor, is described. The reaction of
Publikováno v:
Synthetic Communications. 26:4699-4710
A synthesis of terfenadine carboxylate, 1, a metabolite of terfenadine 2, is described. In the key step, the sodium salt of 2-(4-bromophenyl)-2-methylpropionic acid, 7, was lithiated via a metal-halogen exchange using t-BuLi and subsequently condense
Publikováno v:
The Journal of Organic Chemistry. 49:1013-1021
Synthese a partir de la substitution nucleophile SN2 du bromo-3 pyrroline-1 carboxylate-2 de methyle par le N-t-butoxycarbonylphenylalanyl (=X)-2' ethyl-4 phenolate de thallium suivie de reduction, de cyclisation de la benzyloxycarbonyl-1 t-butoxycar
Publikováno v:
The Journal of Organic Chemistry. 50:3997-4005
Autor:
Kau-Ming Chen, Madeleine M. Joullié
Publikováno v:
Organic Preparations and Procedures International. 18:109-112
Autor:
Madeleine M. Joullié, Kau-Ming Chen
Publikováno v:
Chemischer Informationsdienst. 17
Autor:
Kau-Ming Chen, Madeleine M. Joullié
Publikováno v:
Tetrahedron Letters. 23:4567-4568
An efficient three-step synthesis of Colletochlorin D from orcinol has been achieved.
Akademický článek
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Publikováno v:
In Tetrahedron: Asymmetry 1990 1(10):703-706