Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Katy West"'
Autor:
Olmo Sonzogni, Daniel E. Zak, Maria Stella Sasso, Rochelle Lear, Alice Muntzer, Manuela Zonca, Katy West, Brian R. Champion, James B. Rottman
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Although chimeric antigen receptor (CAR) T cells have emerged as highly effective treatments for patients with hematologic malignancies, similar efficacy has not been achieved in the context of solid tumors. There are several reasons for this dispari
Externí odkaz:
https://doaj.org/article/fc074a31364141db8230cf60b8ebcac2
Autor:
Janet Lei, Egon J. Jacobus, William K. Taverner, Kerry D. Fisher, Silvio Hemmi, Katy West, Lorna Slater, Fred Lilley, Alice Brown, Brian Champion, Margaret R. Duffy, Len W. Seymour
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-16 (2018)
Abstract Background Oncolytic viruses are currently experiencing accelerated development in several laboratories worldwide, with some forty-seven clinical trials currently recruiting. Many oncolytic viruses combine targeted cytotoxicity to cancer cel
Externí odkaz:
https://doaj.org/article/44a96f0e06e746ad9b16a6d3e39bf2b3
Autor:
Manuela Zonca, Katy West, Carla Cerqueira, Alice Muntzer, Rochelle Lear, Samuel Hardy, Darren Plumb, Maria Stella Sasso, Eva Vainiute, Tae Hyun Jang, Samantha Bucktrout, Brian Champion
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Maria Stella Sasso, Rachel Bergin, Manuela Zonca, Eva Vainiute, Tae Hyun Jang, Zahra Oubihi, Meg Snowden, Alice Muntzer, Carla Cerqueira, Rochelle Lear, Katy West, Brian Champion
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Maria Stella Sasso, Rachel Bergin, Rochelle Lear, Darren Plumb, Manuela Zonca, Eva Vainiute, Meg Snowden, Tae Hyun Jang, Alice Muntzer, Carla C. Cerqueira, Katy West, Samantha Bucktrout, Brian R. Champion
Publikováno v:
Cancer Research. 83:5746-5746
Efficacy of Chimeric Antigen Receptor (CAR) T cell therapy against solid tumors is hampered by multiple barriers, including tumor-associated immunosuppression, poor CAR-T cell trafficking into solid tumor masses and shortage of highly expressed cance
Publikováno v:
Marine and Coastal Fisheries. 11:393-413
Autor:
Katy West, Daniel Zak, Rochelle Lear, James B. Rottman, Alice Muntzer, Brian Robert Champion, Olmo Sonzogni
Publikováno v:
Cancer Research. 81:1582-1582
Chimeric antigen receptor (CAR) T cell therapy is an effective treatment for hematologic malignancies but has demonstrated limited efficacy in solid tumors. This is largely attributed to the immunosuppressive tumor microenvironment (TME) that impairs
Autor:
Elena Ivanova, Moataz Noureddine, John Wain, Sylvia V Alarcon, Elizabeth Isaacson, Katy West, David A. Barbie, Brian Robert Champion, Christopher S. Lathan, Cloud P. Paweletz
Publikováno v:
Cancer Research. 81:1710-1710
Tumor-Specific Immuno-Gene (T-SIGn) cancer gene therapy vectors, which are based on the oncolytic adenovirus enadenotucirev, carry a gene cassette encoding combinations of human transgenes under control of the virus major late promoter (MLP) which re
Autor:
Margaret R. Duffy, Len Seymour, Lorna Slater, Janet Lei, Silvio Hemmi, Brian R. Champion, Katy West, Fred Lilley, Kerry D. Fisher, Alice Brown, Egon J. Jacobus, William K. Taverner
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-16 (2018)
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-16 (2018)
Background Oncolytic viruses are currently experiencing accelerated development in several laboratories worldwide, with some forty-seven clinical trials currently recruiting. Many oncolytic viruses combine targeted cytotoxicity to cancer cells with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7a5e7b3014a547ffe74b61fdbadf01
https://doi.org/10.1186/s40425-018-0350-x
https://doi.org/10.1186/s40425-018-0350-x
Autor:
Marilena Patsalidou, Paul Cockle, Matthieu Besneux, Lorna Slater, Katy West, Nalini Marino, Alice Brown, Sam Illingworth, Manuela Zonca, Gianfranco di Genova, Stefania Fedele, Fred Lilley, Ana Marta Silva, Darren Plumb, Brian Robert Champion
Publikováno v:
Cancer Research. 79:5013-5013
NG-641 is a modified variant of enadenotucirev (EnAd), an Ad11p/Ad3 chimeric group B adenovirus, which retains all the functional properties of enadenotucirev while also expressing transgenes designed to target breakdown of the stromal barrier and im