Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Katy M. Alden"'
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Cryptococcus neoformans is an important human fungal pathogen for which the external environment is its primary niche. Previous work has shown that two nonessential acetyl-CoA metabolism enzymes, ATP-citrate lyase (ACL1) and acetyl-CoA synth
Externí odkaz:
https://doaj.org/article/bd16bbc803804fdeb26e1007ccc8eab4
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Cryptococcus neoformans is an environmental yeast and an opportunistic human pathogen. The ability to cause disease depends on the ability to adapt to the human host. Previous studies implicated infectivity-related kinase 3 (IRK3, CNAG_03048
Externí odkaz:
https://doaj.org/article/186a109b7d36473eb4575083a549f2f3
Autor:
Jan Abendroth, Katy M Alden, Jameson Bullen, Taiwo E Esan, Timothy J. Hagen, Damian J. Krysan, Nicholas D DeBouver, Daniel M Murante, Andrew J. Jezewski, Brandy Calhoun, David A. Fox, Kristy T Potts
Publikováno v:
ACS Chemical Biology
Acetyl CoA synthetases (ACSs) are Acyl-CoA/NRPS/Luciferase (ANL) superfamily enzymes that couple acetate with CoA to generate acetyl CoA, a key component of central carbon metabolism in eukaryotes and prokaryotes. Normal mammalian cells are not depen