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Autor:
Deborah H. Slee, Truc N. Nguyen, Mary Kish, Michael J. Newman, Stephen J. Mcconnell, Katy Lundeen, Abhijit S. Bhat
Publikováno v:
Journal of Medicinal Chemistry. 46:1120-1122
The regulation of lipid metabolism and it's effect on glucose control and diabetes has received intense interest. Hormone-sensitive lipase (HSL) is a vital enzyme in lipid metabolism. A series of novel pyrrolopyrazinediones has been discovered that d