Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Katy A. Chalmers"'
Autor:
Sara T. Brookes, Katy A. Chalmers, Kerry N. L. Avery, Karen Coulman, Jane M. Blazeby, on behalf of the ROMIO study group
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Core outcome set (COS) developers increasingly employ Delphi surveys to elicit stakeholders’ opinions of which outcomes to measure and report in trials of a particular condition or intervention. Research outside of Delphi survey
Externí odkaz:
https://doaj.org/article/5e38fcd64cbb40dd943c5e9927b9bcfd
Autor:
Clare Evans, Doug West, Kerry N L Avery, Timothy J.P. Batchelor, Katy A Chalmers, Rakesh Krishnadas, Jane M Blazeby, Gianluca Casali, Eveline Internullo
Publikováno v:
Annals of Surgical Oncology
Background Video-assisted thoracoscopic surgery (VATS) approaches are increasingly used in lung cancer surgery, but little is known about their impact on patients’ health-related quality of life (HRQL). This prospective study measured recovery and
Autor:
Andrew Carr, Marion K Campbell, David J Beard, Natalie S Blencowe, Katy A Chalmers, Carmen Tsang, Jonathan Cook, Ava Lorenc, Sian Cousins, Jane M Blazeby
Publikováno v:
Journal of Clinical Epidemiology
Cousins, S, Blencowe, N S, Tsang, C, Lorenc, A, Chalmers, K, Carr, A J, Campbell, M K, Cook, J A, Beard, D J & Blazeby, J M 2020, ' Reporting of key methodological issues in placebo-controlled trials of surgery needs improvement : a systematic review ', Journal of Clinical Epidemiology, vol. 119, pp. 109-116 . https://doi.org/10.1016/j.jclinepi.2019.11.016
Cousins, S, Blencowe, N S, Tsang, C, Lorenc, A, Chalmers, K, Carr, A J, Campbell, M K, Cook, J A, Beard, D J & Blazeby, J M 2020, ' Reporting of key methodological issues in placebo-controlled trials of surgery needs improvement : a systematic review ', Journal of Clinical Epidemiology, vol. 119, pp. 109-116 . https://doi.org/10.1016/j.jclinepi.2019.11.016
Objectives To examine key methodological considerations for using a placebo intervention in randomized controlled trials (RCTs) evaluating invasive procedures, including surgery. Study Design and Setting RCTs comparing an invasive procedure with a pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d885c569c517332db99130a4bd8744
https://ora.ox.ac.uk/objects/uuid:fad7af53-e66c-430c-a481-7a806b4ae361
https://ora.ox.ac.uk/objects/uuid:fad7af53-e66c-430c-a481-7a806b4ae361
Autor:
Ameen Mardanpour, Andrew Carr, David J Beard, Carmen Tsang, Katy A Chalmers, Sian Cousins, Marion K Campbell, Natalie S Blencowe, Jane M Blazeby, Jonathan Cook
Publikováno v:
Cousins, S, Blencowe, N S, Tsang, C, Chalmers, K, Mardanpour, A, Carr, A J, Campbell, M K, Cook, J A, Beard, D J & Blazeby, J M 2020, ' Optimizing the design of invasive placebo interventions in randomized controlled trials ', British Journal of Surgery . https://doi.org/10.1002/bjs.11509
Cousins, S E, Blencowe, N S, Tsang, C, Chalmers, K A, Mardanpour, A, Carr, A, Campbell, M K, Cook, J, Beard, D & Blazeby, J M 2020, ' Optimizing the design of invasive placebo interventions in randomized controlled trials ', British Journal of Surgery, vol. 107, no. 9, pp. 1114-1122 . https://doi.org/10.1002/bjs.11509
The British Journal of Surgery
Cousins, S E, Blencowe, N S, Tsang, C, Chalmers, K A, Mardanpour, A, Carr, A, Campbell, M K, Cook, J, Beard, D & Blazeby, J M 2020, ' Optimizing the design of invasive placebo interventions in randomized controlled trials ', British Journal of Surgery, vol. 107, no. 9, pp. 1114-1122 . https://doi.org/10.1002/bjs.11509
The British Journal of Surgery
Background Placebo‐controlled trials play an important role in the evaluation of healthcare interventions. However, they can be challenging to design and deliver for invasive interventions, including surgery. In‐depth understanding of the compone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920012da387504f25d605f61e61bf776
https://research-information.bris.ac.uk/en/publications/optimizing-the-design-of-invasive-placebo-interventions-in-randomized-controlled-trials(fd1f34fa-5fbd-47ea-a9d6-169da4ec000b).html
https://research-information.bris.ac.uk/en/publications/optimizing-the-design-of-invasive-placebo-interventions-in-randomized-controlled-trials(fd1f34fa-5fbd-47ea-a9d6-169da4ec000b).html
Autor:
Sanjeeva Kariyawasam, Katy A Chalmers, James Chrichton, Ceri Rowlands, Natalie S Blencowe, Sean Strong, Sarah K Richards, John Mason, Daniel Stevens, Laura Gould, Victoria Pegna, Jane M Blazeby, Katie Whale, Jelena Savović, Noah Howes
Publikováno v:
The British Journal of Surgery
Savović, J, Blencowe, N, Strong, S, Howes, N, Chalmers, K, Chrichton, J, Gould, L, Kariyawasam, S, Mason, J, Pegna, V, Richards, S, Rowlands, C, Stevens, D, Whale, K & Blazeby, J 2017, ' Methodological overview of systematic reviews to establish the evidence base for emergency general surgery ', British Journal of Surgery, vol. 104, no. 5, pp. 513-524 . https://doi.org/10.1002/bjs.10476
Savović, J, Blencowe, N, Strong, S, Howes, N, Chalmers, K, Chrichton, J, Gould, L, Kariyawasam, S, Mason, J, Pegna, V, Richards, S, Rowlands, C, Stevens, D, Whale, K & Blazeby, J 2017, ' Methodological overview of systematic reviews to establish the evidence base for emergency general surgery ', British Journal of Surgery, vol. 104, no. 5, pp. 513-524 . https://doi.org/10.1002/bjs.10476
Background The evidence for treatment decision‐making in emergency general surgery has not been summarized previously. The aim of this overview was to review the quantity and quality of systematic review evidence for the most common emergency surgi
Autor:
Martyn Lee Humphreys, Christopher Streets, Chris A Rogers, Naheed Farooq, Anni Skilton, Kerry N L Avery, Timothy J. Underwood, James P. Byrne, Newton Wong, Carolyn Hindmarsh, Grant Sanders, Rachel Cm Brierley, Richard J E Skipworth, Natalie S Blencowe, Robin A Wickens, Kish Pursnani, Bilal Alkhaffaf, Joanna Nicklin, R Berrisford, Nicola Rea, Simon L. Parsons, Jill Cooke, Alexander P. Boddy, Richard Krysztopik, Chris Metcalfe, David J. Bowrey, William Hollingworth, Fergus Noble, Arun Ariyarathenam, Marcus Jepson, Rachel Schranz, Ram Chaparala, Rebecca J Houlihan, David Exon, Paul Wilkerson, Tim Wheatley, Jamie Kelly, Graeme Couper, Lucy Culliford, Sally Maitland, Rachael Heys, Caoimhe Rice, Chris Deans, Sukhbir Ubhi, Lucy Howie, R S Vohra, James A Catton, Jenny L Donovan, CP Barham, Jane M Blazeby, Peter Lamb, Katy A Chalmers, Alexandra Williams, Sian Cousins, Paul Turner, Neil T. Welch, Dan Titcomb, Aida Moure-Fernandez, Khurshid Akhtar, Vinutha Daya Shetty, Rachel Melhado, Andrew Hollowood, Robert N. Williams, Daisy Gaunt, Joanne Smith, Benjamin Howes, Jackie Elliott
Publikováno v:
BMJ Open
Brierley, RC, Gaunt, D, Metcalfe, C, Blazeby, JM, Blencowe, NS, Jepson, M, Berrisford, RG, Avery, KNL, Hollingworth, W, Rice, CT, Moure-Fernandez, A, Wong, N & Barham, CP 2019, ' Laparoscopically assisted versus open oesophagectomy for patients with oesophageal cancer-the Randomised Oesophagectomy: Minimally Invasive or Open (ROMIO) study: protocol for a randomised controlled trial (RCT). ', BMJ Open . https://doi.org/10.1136/bmjopen-2019-030907
Brierley, R C M, Gaunt, D M, Metcalfe, C, Blazeby, J M, Blencowe, N S, Jepson, M, Berrisford, R, Avery, K N L, Hollingworth, W, Rice, C, Moure Fernandez, A, Wong, N A C S, Nicklin, J K, Skilton, A, Boddy, A P, Byrne, J, Underwood, T, Vohra, R S, Catton, J A, Pursnani, K, Melhado, R, Alkhaffaf, B, Krysztopik, R, Lamb, P, Culliford, L A, Rogers, C A, Howes, B, Chalmers, K A, Cousins, S E, Elliott, J, Donovan, J L, Heys, R L, Wickens, R A, Wilkeron, P, Hollowood, A, Streets, C G, Titcomb, D R, Humphreys, M L, Wheatley, T, Sanders, G, Ariyarathenam, A, Kelly, J, Noble, F, Couper, G, Skipworth, R J E, Deans, C, Ubhi, S, Williams, R, Bowrey, D, Exon, D, Turner, P, Shetty, V, Chaparala, R, Akhtar, K, Farooq, N, Parsons, S, Welch, N, Houlihan, R, Smith, J, Schranz, R, Rea, N, Cooke, J, Williams, A, Hindmarsh, C, Maitland, S, Howie, L & Barham, C P 2019, ' Laparoscopically assisted vs open oesophagectomy for patients with oesophageal cancer – the ROMIO (Randomised Oesophagectomy : Minimally Invasive or Open) study: protocol for a randomized controlled trial (RCT) ', BMJ Open, vol. 9, e030907 . https://doi.org/10.1136/bmjopen-2019-030907
Brierley, R, Gaunt, D M, Metcalfe, C, Blazeby, J M, Blencowe, N S, Jepson, M, Berrisford, R, Avery, K N L, Hollingworth, W, Rice, C T, Moure-Fernandez, A, Wong, N A, Nicklin, J, Skilton, A, Boddy, A, Byrne, J, Underwood, T, Vohra, R, Catton, J A, Pursnani, K, Melhado, R, Alkhaffaf, B, Krysztopik, R, Lamb, P, Culliford, L A, Rogers, C A, Howes, B, Chalmers, K, Cousins, S, Elliott, J, Donovan, J, Heys, R, Wickens, R A, Wilkerson, P, Hollowood, A, Streets, C, Titcomb, D, Humphreys, M L, Wheatley, T, Sanders, G, Ariyarathenam, A, Kelly, J, Noble, F, Couper, G W, Skipworth, R J E, Deans, C, Ubhi, S, Williams, R, Bowrey, D, Exon, D, Turner, P, Shetty, V, Chaparala, R, Akhtar, K, Farooq, N, Parsons, S L, Welch, N T, Houlihan, R J, Smith, J, Schranz, R, Rea, N, Cooke, J, Williams, A, Hindmarsh, C, Maitland, S, Howie, L & Barham, C P 2019, ' Laparoscopically assisted vs open oesophagectomy for patients with oesophageal cancer – the ROMIO (Randomised Oesophagectomy: Minimally Invasive or Open) study: protocol for a randomized controlled trial (RCT) ', BMJ Open . https://doi.org/10.1136/bmjopen-2019-030907
Brierley, RC, Gaunt, D, Metcalfe, C, Blazeby, JM, Blencowe, NS, Jepson, M, Berrisford, RG, Avery, KNL, Hollingworth, W, Rice, CT, Moure-Fernandez, A, Wong, N & Barham, CP 2019, ' Laparoscopically assisted versus open oesophagectomy for patients with oesophageal cancer-the Randomised Oesophagectomy: Minimally Invasive or Open (ROMIO) study: protocol for a randomised controlled trial (RCT). ', BMJ Open . https://doi.org/10.1136/bmjopen-2019-030907
Brierley, R C M, Gaunt, D M, Metcalfe, C, Blazeby, J M, Blencowe, N S, Jepson, M, Berrisford, R, Avery, K N L, Hollingworth, W, Rice, C, Moure Fernandez, A, Wong, N A C S, Nicklin, J K, Skilton, A, Boddy, A P, Byrne, J, Underwood, T, Vohra, R S, Catton, J A, Pursnani, K, Melhado, R, Alkhaffaf, B, Krysztopik, R, Lamb, P, Culliford, L A, Rogers, C A, Howes, B, Chalmers, K A, Cousins, S E, Elliott, J, Donovan, J L, Heys, R L, Wickens, R A, Wilkeron, P, Hollowood, A, Streets, C G, Titcomb, D R, Humphreys, M L, Wheatley, T, Sanders, G, Ariyarathenam, A, Kelly, J, Noble, F, Couper, G, Skipworth, R J E, Deans, C, Ubhi, S, Williams, R, Bowrey, D, Exon, D, Turner, P, Shetty, V, Chaparala, R, Akhtar, K, Farooq, N, Parsons, S, Welch, N, Houlihan, R, Smith, J, Schranz, R, Rea, N, Cooke, J, Williams, A, Hindmarsh, C, Maitland, S, Howie, L & Barham, C P 2019, ' Laparoscopically assisted vs open oesophagectomy for patients with oesophageal cancer – the ROMIO (Randomised Oesophagectomy : Minimally Invasive or Open) study: protocol for a randomized controlled trial (RCT) ', BMJ Open, vol. 9, e030907 . https://doi.org/10.1136/bmjopen-2019-030907
Brierley, R, Gaunt, D M, Metcalfe, C, Blazeby, J M, Blencowe, N S, Jepson, M, Berrisford, R, Avery, K N L, Hollingworth, W, Rice, C T, Moure-Fernandez, A, Wong, N A, Nicklin, J, Skilton, A, Boddy, A, Byrne, J, Underwood, T, Vohra, R, Catton, J A, Pursnani, K, Melhado, R, Alkhaffaf, B, Krysztopik, R, Lamb, P, Culliford, L A, Rogers, C A, Howes, B, Chalmers, K, Cousins, S, Elliott, J, Donovan, J, Heys, R, Wickens, R A, Wilkerson, P, Hollowood, A, Streets, C, Titcomb, D, Humphreys, M L, Wheatley, T, Sanders, G, Ariyarathenam, A, Kelly, J, Noble, F, Couper, G W, Skipworth, R J E, Deans, C, Ubhi, S, Williams, R, Bowrey, D, Exon, D, Turner, P, Shetty, V, Chaparala, R, Akhtar, K, Farooq, N, Parsons, S L, Welch, N T, Houlihan, R J, Smith, J, Schranz, R, Rea, N, Cooke, J, Williams, A, Hindmarsh, C, Maitland, S, Howie, L & Barham, C P 2019, ' Laparoscopically assisted vs open oesophagectomy for patients with oesophageal cancer – the ROMIO (Randomised Oesophagectomy: Minimally Invasive or Open) study: protocol for a randomized controlled trial (RCT) ', BMJ Open . https://doi.org/10.1136/bmjopen-2019-030907
IntroductionSurgery (oesophagectomy), with neoadjuvant chemo(radio)therapy, is the main curative treatment for patients with oesophageal cancer. Several surgical approaches can be used to remove an oesophageal tumour. The Ivor Lewis (two-phase proced
Autor:
Katy A Chalmers, Christopher Lee, Maya El Hindy, Patrick G. Kehoe, Vinood B. Patel, Mohammed Hezwani, Esther Odeleye, Seth Love, Myra E. Conway, Jonathon Hull
Publikováno v:
Journal of Alzheimer's Disease. 45:891-905
BACKGROUND The human branched chain aminotransferases (hBCATm, mitochondrial and hBCATc, cytosolic) are major contributors to brain glutamate production. This excitatory neurotransmitter is thought to contribute to neurotoxicity in neurodegenerative
Autor:
David Mahon, Noah Howes, Richard Welbourn, Robert Andrews, Katie Whale, Katy A Chalmers, Karen D Coulman, Jane M Blazeby, James P. Byrne, Jelena Savović, James Hopkins, Robert N. Whistance
Publikováno v:
Obesity Reviews. 16:88-106
Summary Outcome reporting in bariatric surgery needs a core outcome set (COS), an agreed minimum set of outcomes reported in all studies of a particular condition. The aim of this study was to summarize outcome reporting in bariatric surgery to infor
Autor:
Robert H. Perry, Elaine K. Perry, Gordon K. Wilcock, Seth Love, Katy A Chalmers, Clive Ballard, Harry V. Vinters
Cholinesterase inhibitors (ChEIs) are widely used for the symptomatic treatment of Alzheimer's disease (AD). In vitro and in animal studies, ChEIs have been shown to influence the processing of Abeta and the phosphorylation of tau, proteins that are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9a5b402234807069da5ca9e3feb085
https://doi.org/10.1007/s00415-009-5000-2
https://doi.org/10.1007/s00415-009-5000-2
Publikováno v:
University of Bristol-PURE
Abnormalities of cerebral white matter are present in a majority of patients with Alzheimer's disease (AD) and probably contribute to motor dysfunction and cognitive impairment. The white matter abnormalities are usually attributed to degenerative va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98655ce505a98327eef08f0b19cf12d0
https://ora.ox.ac.uk/objects/uuid:a85608eb-965a-4d27-98b5-7b685449643d
https://ora.ox.ac.uk/objects/uuid:a85608eb-965a-4d27-98b5-7b685449643d