Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Katsuyuki Nishiki"'
Autor:
Kazuhiro Kitazumi, Saburo Aimoto, Keizo Ohnaka, Hajime Nawata, Ryoichi Takayanagi, Toshiharu Shiba, Chikahisa Takasaki, Kenji Tasaka, Katsuyuki Nishiki, Yasuo Furukawa
Publikováno v:
European Journal of Pharmacology. 198:165-169
The three chimera peptides of sarafotoxins S6b (SRTb) and S6c (SRTc), [Thr 2 SRTb, [Asn 4 ]SRTb and [Glu 9 ]SRTb, were synthesized chemically. From the comparisons of lethality, vasoconstrictor activity and receptor binding activity of SRTb, SRTa ([A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d58121b513e7e05b2584a8f11e4744
https://doi.org/10.1016/0014-2999(91)90616-x
https://doi.org/10.1016/0014-2999(91)90616-x
Autor:
Masayuki Niwa, Tatsuo Hosoya, S. Nagashima, Akira Hishida, Katsuyuki Nishiki, Toshihiko Uematsu
Publikováno v:
European Journal of Clinical Pharmacology. 60
Intravenous administration of an everninomicin antibiotic, SCH27899 (Ziracin), in healthy subjects caused a marked decrease in serum urate by increasing its urinary excretion, as well as an increase in serum bilirubin in a dose-dependent manner. To c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2457819f4b4f3a13159332135091dc1
https://doi.org/10.1007/s00228-004-0755-y
https://doi.org/10.1007/s00228-004-0755-y
Publikováno v:
Antimicrobial Agents and Chemotherapy. 36:481-483
LJC 10,627 is a new parenteral carbapenem antibiotic. LJC 10,627 stability against human renal dehydropeptidase-I was compared with that of imipenem. Hydrolysis of this compound was not detectable by spectrophotometrical assay. Even after a 2-h incub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9125e9365c6cd5afd9fd953faf3e6af8
https://doi.org/10.1128/aac.36.2.481
https://doi.org/10.1128/aac.36.2.481
Autor:
Katsuyuki Nishiki, Mutsuyoshi Kazama, Hiroyuki Hamada, Katsufumi Sakyo, Shuichi Horie, Hidemi Ishii
Publikováno v:
Blood. 86(1)
Thrombomodulin (TM) is an anticoagulant endothelial cell surface glycoprotein containing six tandem epidermal growth factor (EGF)-like structures. We prepared a recombinant TM peptide (rTME1–6, from R214GHWA to DSGK466 of native TM) composed of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b29ffa6a0c45f8cd657f0c86bea3bf0
https://pubmed.ncbi.nlm.nih.gov/7795228
https://pubmed.ncbi.nlm.nih.gov/7795228
The toxicity of LJC 10,627 to the central nervous system of rats was evaluated by examining the effects of the compound on gamma-aminobutyric acidA, benzodiazepine, and glycine receptor binding in rat synaptic membranes and on the induction of behavi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed6ac3ca3316d3552527ec6bb059da4
https://europepmc.org/articles/PMC187638/
https://europepmc.org/articles/PMC187638/
Autor:
Katsuyuki Nishiki, M Yoshida, M Hikida, Kimiko Ubukata, Y Furukawa, K Tashiro, Masatoshi Konno, S Mitsuhashi
Publikováno v:
Antimicrobial agents and chemotherapy. 34(6)
The in vitro activity of LJC10,627, a new carbapenem, was compared with those of imipenem and ceftazidime. LJC10,627 had broad-spectrum activity against gram-positive and gram-negative clinical isolates. The MICs of this compound for 90% of members o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f792bcfc6b43f770339ca082eba8c2e3
https://pubmed.ncbi.nlm.nih.gov/2203313
https://pubmed.ncbi.nlm.nih.gov/2203313
Autor:
Kazuhiro Kitazumi, Toshiharu Shiba, Yasuo Furukawa, Chikahisa Takasaki, Kenji Tasaka, Katsuyuki Nishiki
Publikováno v:
FEBS letters. 260(2)
Sarafotoxins (SRTa, SRTb and SRTc) as well as endothelin-1 (ET-1) produced vasoconstrictions in rat thoracic aorta, rat isolated perfused mesentery and pithed rat in various of extents. The potency was ET-1 greater than SRTb greater than SRTa greater
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a05f24f5d709dd8da1db3adea1ab75
https://pubmed.ncbi.nlm.nih.gov/2404800
https://pubmed.ncbi.nlm.nih.gov/2404800
Autor:
Katsuyuki Nishiki, Masuhito Yoshida, Muneo Hikida, Yoshiyuki Yamazaki, Kousuke Kawashima, Susumu Mitsuhashi
Publikováno v:
The Journal of Antibiotics. 48:891-892
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4d449ca705c6ce2a0be63c486790a1
https://doi.org/10.7164/antibiotics.48.891
https://doi.org/10.7164/antibiotics.48.891
Electroencephalographic effects of CL284,846, a new non-benzodiazepine sedative-hypnotic, in rabbits
Autor:
Megumi Mori, Kazuhiro Kitazumi, Hiroto Suzuki, Katsuyuki Nishiki, Toshiharu Shiba, Hideaki Noguchi
Publikováno v:
Japanese Journal of Pharmacology. 71:181
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5acadb36e94d81fdba5f8c11f24dc0f
https://doi.org/10.1016/s0021-5198(19)36964-1
https://doi.org/10.1016/s0021-5198(19)36964-1
Publikováno v:
Japanese Journal of Pharmacology. 71:181
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42f10e80454b6f6c85db9adb18ab0910
https://doi.org/10.1016/s0021-5198(19)36965-3
https://doi.org/10.1016/s0021-5198(19)36965-3