Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Katsuyuki Mitomo"'
Autor:
Katsuyuki Mitomo, Ping Huang, Takao Hamakubo, Masato Yasui, Kaori Miyazaki-Komine, Yoshiki Takai, Katsushi Koda, Toshiko Sakihama, Yoichiro Abe, Hiroko Iwanari, Yoshiaki Toyama, Tatsuro Misu, Osamu Kusano-Arai, Kazuo Fujihara
Publikováno v:
British Journal of Pharmacology. 173:103-114
Background and Purpose Most of the cases of neuromyelitis optica (NMO) are characterized by the presence of an autoantibody, NMO-IgG, which recognizes the extracellular domains of the water channel, aquaporin-4. Binding of NMO-IgG to aquaporin-4 expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::393b3ab1affe6a89b6de9266228df2a9
https://doi.org/10.1111/bph.13340
https://doi.org/10.1111/bph.13340
Autor:
Katsuyuki Mitomo, Yuko Tagawa, Hidetaka Yakura, Tatsuo Katagiri, Mami Ogimoto, Noriyuki Watanabe, Kazuya Mizuno
Publikováno v:
The Journal of Immunology. 169:778-786
Src homology region 2 domain-containing phosphatase 1 (SHP-1) is a key mediator in lymphocyte differentiation, proliferation, and activation. We previously showed that B cell linker protein (BLNK) is a physiological substrate of SHP-1 and that B cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a997d4976e5b1f691fa9cbcfedaf46a
https://doi.org/10.4049/jimmunol.169.2.778
https://doi.org/10.4049/jimmunol.169.2.778
Autor:
Kaori, Miyazaki-Komine, Yoshiki, Takai, Ping, Huang, Osamu, Kusano-Arai, Hiroko, Iwanari, Tatsuro, Misu, Katsushi, Koda, Katsuyuki, Mitomo, Toshiko, Sakihama, Yoshiaki, Toyama, Kazuo, Fujihara, Takao, Hamakubo, Masato, Yasui, Yoichiro, Abe
Publikováno v:
British journal of pharmacology. 173(1)
Most of the cases of neuromyelitis optica (NMO) are characterized by the presence of an autoantibody, NMO-IgG, which recognizes the extracellular domains of the water channel, aquaporin-4. Binding of NMO-IgG to aquaporin-4 expressed in end-feet of as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e4a850041945f5a8062a9fe1417640e
https://pubmed.ncbi.nlm.nih.gov/26398585
https://pubmed.ncbi.nlm.nih.gov/26398585
Autor:
Tsukasa Ohmori, Jun Mimuro, Katsuhiro Takano, Seiji Madoiwa, Yuji Kashiwakura, Akira Ishiwata, Masanori Niimura, Katsuyuki Mitomo, Toshiaki Tabata, Mamoru Hasegawa, Keiya Ozawa, Yoichi Sakata
Publikováno v:
The FASEB Journal. 20:1522-1524
Platelets release several mediators that modify vascular integrity and hemostasis. In the present study, we developed a technique for efficient transgene expression in platelets in vivo and examined whether this targeted-gene-product delivery system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72f375b9285a1c76f0ea87ef72a1079
https://doi.org/10.1096/fj.05-5161fje
https://doi.org/10.1096/fj.05-5161fje
Autor:
Lucinda Somerton, Yasuji Ueda, Mamoru Hasegawa, Uta Griesenbach, Cuixiang Meng, Felix M. Munkonge, Gad Frankel, Sara Escudero-Garcia, Makoto Inoue, Eric W.F.W. Alton, Andrea Brum, Mario Chan, Raymond Farley, Katsuyuki Mitomo, Stefania Xenariou, Charanjit Singh, Eiji Akiba, Toshiaki Tabata
Gene therapy for cystic fibrosis (CF) is making encouraging progress into clinical trials. However, further improvements in transduction efficiency are desired. To develop a novel gene transfer vector that is improved and truly effective for CF gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17b8d1ce4721b8d68ab5c9ca7623b49
https://europepmc.org/articles/PMC2889732/
https://europepmc.org/articles/PMC2889732/
Autor:
Jun Mimuro, Akira Ishiwata, Hidenori Suzuki, Katsuyuki Mitomo, Yoichi Sakata, Mamoru Hasegawa, Seiji Madoiwa, Tsukasa Ohmori, Yuji Kashiwakura
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 16(8)
Platelets are receiving much attention as novel target cells to secrete a coagulation factor for hemophilia gene therapy. In order to extend the application of platelet-directed gene therapy, we examined whether ectopic expression of activated factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4065e959dade070f9e0a4409ebdac37b
https://pubmed.ncbi.nlm.nih.gov/18523449
https://pubmed.ncbi.nlm.nih.gov/18523449
Publikováno v:
Molecular and Cellular Biology. 10:561-568
Interleukin-6 (IL-6) is one of the major mediators of inflammation, and its expression is inducible by the other inflammatory lymphokines, interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF-alpha). We demonstrate that a common IL-6 promoter el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a2c5f5e681690885c58b4ed42ddb12
https://doi.org/10.1128/mcb.10.2.561-568.1990
https://doi.org/10.1128/mcb.10.2.561-568.1990
Autor:
Yukio Sudo, Katsushi Kouda, Yoshinori Ukai, Katsuyuki Mitomo, Youichi Aikawa, Fumiko Nomura, Lilin Zhang, Yoko Kayukawa, Gene Kurosawa, Kazuhiro Morishita, Romi Kodaka, Yoshikazu Kurosawa
Publikováno v:
Cancer Research. 73:4323-4323
Transferrin receptor (TfR) is a type II transmembrane glycoprotein regulating intracellular uptake of iron, and is therefore involved in cell survival and proliferation. TfR has been reported to be more abundantly expressed in dividing cells, e.g. ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05765e101873febd231ab4720989564b
https://doi.org/10.1158/1538-7445.am2013-4323
https://doi.org/10.1158/1538-7445.am2013-4323
Autor:
Ken Ichi Yamamoto, Mami Ogimoto, Katsuyuki Mitomo, Tatsuo Katagiri, Kazuya Mizuno, Yutaka Arimura, Hidetaka Yakura, Siniša Volarević
Stimulation of B cell antigen receptor (BCR) may induce proliferation, differentiation, or apoptosis, depending upon the maturational stage of the cell and the presence or absence of signals transmitted via coreceptors. One such signal is delivered v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3624916b46c6402b3dac53ca645e0e92
https://www.bib.irb.hr/186245
https://www.bib.irb.hr/186245
Autor:
Keisuke Mashima, Kiminori Hasegawa, Mami Ogimoto, Katsuyuki Mitomo, Kazuya Mizuno, Hidetaka Yakura, Hiroaki Yajima, Yutaka Arimura, Tatsuo Katagiri
Publikováno v:
European journal of immunology. 29(3)
Signaling events leading to B cell growth or apoptosis are beginning to be unravelled, but detailed information is still lacking. To identify signaling molecules involved in B cell antigen receptor (BCR)-initiated pathways, we used the immature B cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c052078b440e1fe89e78e34b132bd7c
https://pubmed.ncbi.nlm.nih.gov/10092092
https://pubmed.ncbi.nlm.nih.gov/10092092