Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Katsuyuki Kusuzaki"'
Autor:
Gemma Di Pompo, Katsuyuki Kusuzaki, Marco Ponzetti, Vito Ferdinando Leone, Nicola Baldini, Sofia Avnet
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1904 (2022)
Current multimodal treatment of bone metastases is partially effective and often associated with side effects, and novel therapeutic options are needed. Acridine orange is a photosensitizing molecule that accumulates in acidic compartments. After pho
Externí odkaz:
https://doaj.org/article/e4af9cfc512a42c1ac565c50543c7275
Autor:
Katsuyuki Kusuzaki, Takao Matsubara, Hiroaki Murata, Mariantonia Logozzi, Elisabetta Iessi, Rossella Di Raimo, Fabrizio Carta, Claudiu T. Supuran, Stefano Fais
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 908-916 (2017)
Photodynamic molecules represent an alternative approach for cancer therapy for their property (i) to be photo-reactive; (ii) to be not-toxic for target cells in absence of light; (iii) to accumulate specifically into tumour tissues; (iv) to be activ
Externí odkaz:
https://doaj.org/article/f76dc04949d74e688c0662decc1a6ca6
Publikováno v:
Journal of Orthopaedic Surgery, Vol 18 (2010)
Tophaceous pseudogout in the knee joint is rare. We report an 82-year-old man who presented with a one-year history of pain and swelling of the right knee joint. Treatment with non-steroidal anti-inflammatory drugs and aspiration of the joint effusio
Externí odkaz:
https://doaj.org/article/f533614e75724385ac15fea42d999008
Autor:
Tomohito Hagi, Kunihiro Asanuma, Takao Matsubara, Katsuyuki Kusuzaki, Hiroaki Murata, Akihiro Sudo, Tomoki Nakamura
Publikováno v:
Photodiagnosis and Photodynamic Therapy. 23:165-170
Background We investigated the long-term clinical efficacy of acridine orange (AO) therapy on the inhibition of local recurrence after marginal or intra-lesional tumor resection in high-grade soft tissue sarcomas (STSs). Methods Our study consisted o
Autor:
Rossella Di Raimo, Stefano Fais, Hiroaki Murata, Fabrizio Carta, Katsuyuki Kusuzaki, Claudiu T. Supuran, Mariantonia Logozzi, Elisabetta Iessi, Takao Matsubara
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 908-916 (2017)
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry
Photodynamic molecules represent an alternative approach for cancer therapy for their property (i) to be photo-reactive; (ii) to be not-toxic for target cells in absence of light; (iii) to accumulate specifically into tumour tissues; (iv) to be activ
Autor:
Emanuela Maria Morello, Marina Martano, Katsuyuki Kusuzaki, Francesco Costa, Nicola Baldini, Federica Sammartano, Sofia Avnet
Publikováno v:
BioMed Research International, Vol 2019 (2019)
BioMed Research International
BioMed Research International
Musculoskeletal sarcomas are rare and aggressive human malignancies affecting bones and soft tissues with severe consequences, in terms of both morbidity and mortality. An innovative technique that combines photodynamic surgery (PDS) and therapy (PDT
Autor:
Tokuhiro Chano, Silvia Lemma, Sofia Avnet, Massimo Dominici, Nicoletta Zini, Margherita Cortini, Nicola Baldini, Giulia Grisendi, Francesca Perut, Katsuyuki Kusuzaki, Angelo De Milito, Paola Pellegrini
Publikováno v:
Oncotarget
// Sofia Avnet 1 , Silvia Lemma 1 , Margherita Cortini 1 , Paola Pellegrini 2 , Francesca Perut 1 , Nicoletta Zini 3, 4 , Katsuyuki Kusuzaki 5 , Tokuhiro Chano 6 , Giulia Grisendi 7 , Massimo Dominici 7 , Angelo De Milito 2 , Nicola Baldini 1, 8 1 Or
Autor:
Kazuya Inoue, Tetsuo Takai, Nicola Baldini, Hitoshi Yoshimura, Shigeo Takai, Katsuyuki Kusuzaki
Publikováno v:
Anticancer Research. 38
Aim We previously found that low-dose X-ray treatment after systemic administration of acridine orange (AO), which is known to have a low toxicity in animals, inhibited tumor growth in experimental studies using mouse osteosarcoma. In this pilot stud
Publikováno v:
Scopus-Elsevier
Acridine orange (AO) is an antimalarial drug that accumulates into acidic cellular compartments. Lysosomes are quite acidic in cancer cells, and on this basis we have demonstrated that photoactivated AO is selectively toxic in sarcomas. However, phot
Publikováno v:
Journal of Cellular and Molecular Medicine
The purpose of the present study was to clarify roles of cytosolic chloride ion (Cl(-) ) in regulation of lysosomal acidification [intra-lysosomal pH (pHlys )] and autophagy function in human gastric cancer cell line (MKN28). The MKN28 cells cultured