Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Katsuyoshi Sunaga"'
Autor:
Bo Yuan, Jingmei Li, Shin-Ich Miyashita, Hidetomo Kikuchi, Meiyan Xuan, Hirokazu Matsuzaki, Naohiro Iwata, Shinya Kamiuchi, Katsuyoshi Sunaga, Takeshi Sakamoto, Yasuhide Hibino, Mari Okazaki
Publikováno v:
Molecules, Vol 27, Iss 19, p 6577 (2022)
The cytotoxicity of a trivalent arsenic derivative (arsenite, AsIII) combined with arenobufagin or gamabufotalin was evaluated in human U-87 glioblastoma cells. Synergistic cytotoxicity with upregulated intracellular arsenic levels was observed, when
Externí odkaz:
https://doaj.org/article/4d4495d3f7594f838dd141bd8cc2b1c7
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 12, Iss 5, Pp 464-469 (2017)
We previously demonstrated that tomato juice (TJ) contains potent mechanism-based inhibitor(s) of CYP3A4. In this study, we investigated the effects of TJ and grapefruit juice (GFJ) on the pharmacokinetics of the CYP3A4-substrate drugs, nifedipine (N
Externí odkaz:
https://doaj.org/article/a4a77f4a695a4cb0981e164aec4e42cf
Autor:
Akihiko Hirose, Tohru Yamazaki, Takeshi Sakamoto, Katsuyoshi Sunaga, Tadashi Tsuda, Atsushi Mitsumoto, Naomi Kudo, Yoichi Kawashima
Publikováno v:
Journal of Pharmacological Sciences, Vol 116, Iss 4, Pp 362-372 (2011)
Abstract.: The effects of 2-(4-chlorophenoxy)-2-methylpropionic acid (clofibric acid) on the formation of oleic acid (18:1) from stearic acid (18:0) and utilization of the 18:1 formed for phosphatidylcholine (PC) formation in endoplasmic reticulum in
Externí odkaz:
https://doaj.org/article/e4dfa00c8f734b929469281c3ab85a3f
Autor:
YUSEI OTAKA, MAKI IZAWA, HIROSHI SAKAGAMI, NORIYOSHI SHIBA, NOBUTOSHI TAKAHASHI, SEI-ICHI TANUMA, SHIGERU AMANO, SHIN UOTA, MEGUMI INOMATA, SATOSHI YOKOSE, KATSUYOSHI SUNAGA, SHINICHIRO HAYASHI, YUKARI KOGA-OGAWA, GIICHIROU NAKAYA, SHINJI KITO
Publikováno v:
In Vivo; Nov/Dec2023, Vol. 37 Issue 6, p2464-2472, 9p
Autor:
Yuki Toguchi, Hidetomo Kikuchi, Yoshio Nishimura, Bo Yuan, Rie Arai, Hidetsura Cho, Katsuyoshi Sunaga
Dihydropyrimidines (DPs), one of the six-membered heterocyclic compounds, are well known to have a wide range of pharmacological activities including anticancer. Recently, our previous studies have demonstrated that 6-unsubstituted 2-thioxo-, 2-oxo-,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a88efdc75deb27d12ce35bae909d4a79
https://doi.org/10.21203/rs.3.rs-2071332/v1
https://doi.org/10.21203/rs.3.rs-2071332/v1
Autor:
MAKI IZAWA, YUSEI OTAKA, HIROSHI SAKAGAMI, SEI-ICHI TANUMA, SHIGERU AMANO, SHIN UOTA, MEGUMI INOMATA, YUKA KATO, HIROSHI KADOKURA, SATOSHI YOKOSE, KATSUYOSHI SUNAGA, YUKARI KOGA-OGAWA, GIICHIROU NAKAYA, SHINJI KITO
Publikováno v:
In Vivo; Jul/Aug2023, Vol. 37 Issue 4, p1540-1551, 12p
Autor:
Yoshio Nishimura, Hidetomo Kikuchi, Takanori Kubo, Rie Arai, Yuki Toguchi, Bo Yuan, Katsuyoshi Sunaga, Hidetsura Cho
Publikováno v:
Chemicalpharmaceutical bulletin. 70(2)
An efficient synthetic method for novel 4,4-disubstituted 3,4-dihydropyrimidin-2(1H)-ones 5 and -thiones 6 was developed. The cyclocondensation reaction of O-methylisourea hemisulfate salt 11 with 8 gives a tautomeric mixture of dihydropyrimidines 12
Autor:
Jingmei Li, Bo Yuan, Meiyan Xuan, Hidetomo Kikuchi, Katsuyoshi Sunaga, Shinya Kamiuchi, Yasuhide Hibino, Hirokazu Matsuzaki, Mari Okazaki
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:3
Autor:
Shiori Yoshida, Nana Toyoda, Satoko Ezawa, Katsuyoshi Sunaga, Hidetomo Kikuchi, Yasuhide Hibino
Publikováno v:
Molecular medicine reports. 22(4)
α‑glucosidase is a key enzyme that plays a role in glucose absorption in the gastrointestinal tract, and the inhibition of its activity induces the prevention of postprandial hyperglycemia. Several α‑glucosidase inhibitors have been used as med
Autor:
Katsuyoshi Sunaga, Hidetomo Kikuchi, Hidetsura Cho, Mari Oguni, Takanori Kubo, Bo Yuan, Yoshio Nishimura, Ibuki Nakakita, Rie Arai, Misaki Ohta
Publikováno v:
Tetrahedron Letters. 76:152913