Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Katsuya Tanabe"'
Publikováno v:
FEBS Open Bio, Vol 13, Iss 8, Pp 1405-1414 (2023)
Wolfram syndrome is a monogenic disease mainly caused by mutations in the WFS1 gene. Mutations in the WFS1 gene give rise to diabetes. Here, we characterized mutant WFS1 proteins by studying the stability of full‐length wild‐type (WT) WFS1, a mis
Externí odkaz:
https://doaj.org/article/50d1e9465cc64119b0b5f9c148a15311
Autor:
Syota Kagawa, Katsuya Tanabe, Makoto Hiromura, Kakuyou Ogawa, Takayuki Koga, Takahiro Maeda, Kikuko Amo-Shiinoki, Hiroyuki Ochi, Yui Ichiki, Shogo Fukuyama, Saori Suzuki, Natsuki Suizu, Takaaki Ohmine, Sakurako Hamachi, Hiroshi Tsuneki, Shigeru Okuya, Toshiyasu Sasaoka, Yukio Tanizawa, Fumihiro Nagashima
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Hachimijiogan (HJG) has originally been used to ameliorate a variety of symptoms associated with low ambient temperatures. However, its pharmacological action in metabolic organs remains unclear. We hypothesized that HJG may modulate metabolic functi
Externí odkaz:
https://doaj.org/article/6a843b8816024421a6964c11f6afff37
Autor:
Shogo Amano, Shigeyuki Suenaga, Kaori Hamamoto, Shoko Yada, Takanori Tsuyama, Shuhei Shinoda, Yuya Tanaka, Yoshihiro Takemoto, Eijiro Harada, Katsuya Tanabe, Shunichiro Asahara, Kazunobu Hoshii, Taro Takami
Publikováno v:
DEN Open, Vol 3, Iss 1, Pp n/a-n/a (2023)
Abstract Herein we report the case of a patient with multiple glucagonomas that have been precisely described with endoscopic ultrasound. A 36‐year‐old woman was referred to our hospital for computed tomography investigation of multiple pancreati
Externí odkaz:
https://doaj.org/article/6c31da87bc1a45e8a3e4134d7aefc53a
Publikováno v:
Heliyon, Vol 7, Iss 2, Pp e06196- (2021)
A 39-year-old man with type 1 diabetes, who had a 4-year history of Graves' disease being treated with propylthiouracil (PTU), had developed sudden hearing loss. However, he showed no other clinical manifestations. Intratympanic administration with d
Externí odkaz:
https://doaj.org/article/98687922ee5c4c0eba785367ab80a845
Autor:
Kikuko Amo-Shiinoki, Katsuya Tanabe, Yoshinobu Hoshii, Hiroto Matsui, Risa Harano, Tatsuya Fukuda, Takato Takeuchi, Ryotaro Bouchi, Tokiyo Takagi, Masayuki Hatanaka, Komei Takeda, Shigeru Okuya, Wataru Nishimura, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe, Takumi Akashi, Tetsuya Yamada, Yoshihiro Ogawa, Eiji Ikeda, Hiroaki Nagano, Yukio Tanizawa
Publikováno v:
JCI Insight, Vol 6, Iss 1 (2021)
Dedifferentiation has been implicated in β cell dysfunction and loss in rodent diabetes. However, the pathophysiological significance in humans remains unclear. To elucidate this, we analyzed surgically resected pancreatic tissues of 26 Japanese sub
Externí odkaz:
https://doaj.org/article/92a308a1444447e78710fef4553a9fd9
Publikováno v:
Journal of Diabetes Research, Vol 2017 (2017)
Type 2 diabetes mellitus (T2DM) results from pancreatic β-cell failure in the setting of insulin resistance. In the early stages of this disease, pancreatic β-cells meet increased insulin demand by both enhancing insulin-secretory capacity and incr
Externí odkaz:
https://doaj.org/article/dc5af6378e0e402b9267513e287d177c
Autor:
Kimie Matsunaga, Katsuya Tanabe, Hiroshi Inoue, Shigeru Okuya, Yasuharu Ohta, Masaru Akiyama, Akihiko Taguchi, Yukari Kora, Naoko Okayama, Yuichiro Yamada, Yasuhiko Wada, Shin Amemiya, Shigetaka Sugihara, Yuzo Nakao, Yoshitomo Oka, Yukio Tanizawa
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106906 (2014)
BACKGROUND: Wolfram syndrome (WFS) is a recessive neurologic and endocrinologic degenerative disorder, and is also known as DIDMOAD (Diabetes Insipidus, early-onset Diabetes Mellitus, progressive Optic Atrophy and Deafness) syndrome. Most affected in
Externí odkaz:
https://doaj.org/article/24509e5a11404243807f239b76ed7a91
Autor:
Katsuya Tanabe, Yang Liu, Syed D Hasan, Sara C Martinez, Corentin Cras-Méneur, Cris M Welling, Ernesto Bernal-Mizrachi, Yukio Tanizawa, Christopher J Rhodes, Erik Zmuda, Tsonwin Hai, Nada A Abumrad, M Alan Permutt
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18146 (2011)
The combination of elevated glucose and free-fatty acids (FFA), prevalent in diabetes, has been suggested to be a major contributor to pancreatic β-cell death. This study examines the synergistic effects of glucose and FFA on β-cell apoptosis and t
Externí odkaz:
https://doaj.org/article/b671a558826147669c4f27ffce82fc99
Autor:
Katsuya Tanabe, Zhonghao Liu, Satish Patel, Bradley W Doble, Lin Li, Corentin Cras-Méneur, Sara C Martinez, Cris M Welling, Morris F White, Ernesto Bernal-Mizrachi, James R Woodgett, M Alan Permutt
Publikováno v:
PLoS Biology, Vol 6, Iss 2, p e37 (2008)
Despite treatment with agents that enhance beta-cell function and insulin action, reduction in beta-cell mass is relentless in patients with insulin resistance and type 2 diabetes mellitus. Insulin resistance is characterized by impaired signaling th
Externí odkaz:
https://doaj.org/article/204fb8f76a4a4489839e941e516b46eb
Autor:
Takayuki Tanabe, Akio Nakajima, Kazuyoshi Fukunaga, Atsushi Nakamura, Tetsuji Suzuki, Katsuya Tanabe, Koichi Sato, Yusaku Yamashita, Takahiro Nakata, Kazuhisa Tanaka, Yukihiro Takahashi
Publikováno v:
Japanese Journal of Extra-Corporeal Technology. 48:277-283
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc68151da9dcea7d921d8aaff99f971c
https://doi.org/10.7130/jject.48.277
https://doi.org/10.7130/jject.48.277