Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Katsuya Sakimura"'
Autor:
Katsuya Sakimura, Takashi Kawai, Reiko Nashida, Yuji Ishida, Kana Harada, Takashi Suzuki, Chihiro Okuma, Gregory M. Cole
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Alzheimer’s disease (AD) is the most common form of dementia. Although drugs focusing on reducing amyloid β slow progression, they fail to improve cognitive function. Deficits in glucose metabolism are reflected in FDG-PET and
Externí odkaz:
https://doaj.org/article/d0cd1b22ce1843a987fdf8ace4913d23
Publikováno v:
International Journal of Endocrinology, Vol 2018 (2018)
In patients with diabetes mellitus (DM), impairments of circadian rhythms, including the sleep–wake cycle, blood pressure, and plasma melatonin concentrations, are frequently observed. Animal models of DM are also reported to show aberrant circadia
Externí odkaz:
https://doaj.org/article/24708d9ebcb643abb1cc685f3654818b
Autor:
Takeshi Ohta, Kazuo Sasagawa, Yukihito Ishii, Katsuya Sakimura, Shinichi Kume, Tatsuya Maekawa
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 45:927-933
Depression is one of the most common psychiatric diseases and is commonly comorbid with type 1 or 2 diabetes mellitus (DM). However, the pathophysiology underlying the depressive state in DM remains poorly understood. Animal models are useful tools t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06c2a6fee0d84ff67a16bf11567931f
https://doi.org/10.1111/1440-1681.12965
https://doi.org/10.1111/1440-1681.12965
Autor:
Keisuke Hirai, Takuto Kojima, Yoshiro Tomimatsu, Takahiko Yano, Kazuyoshi Aso, Yoshikazu Ootani, Yuu Sako, Katsuya Sakimura, Maiko Tanaka
Publikováno v:
Peptides. 95:40-50
The aim of this study was to investigate peripheral and central roles of corticotropin-releasing factor (CRF) in endocrinological and behavioral changes. Plasma adrenocorticotropin (ACTH) concentration was measured as an activity of hypothalamic-pitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4324b30f8e82abf29dc0ade7b7cf9cb
https://doi.org/10.1016/j.peptides.2017.06.009
https://doi.org/10.1016/j.peptides.2017.06.009
Publikováno v:
Journal of Neuroscience Research. 94:888-895
NMDA receptor dysfunctions are hypothesized to underlie the pathophysiology of schizophrenia, and treatment with D-serine (D-Ser), an NMDA receptor coagonist, may improve the clinical symptoms of schizophrenia. Thus, upregulating the synaptic D-Ser l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b7ed939eaf95d571ecf1f7dd38d1488
https://doi.org/10.1002/jnr.23772
https://doi.org/10.1002/jnr.23772
Publikováno v:
International Journal of Endocrinology, Vol 2018 (2018)
International Journal of Endocrinology
International Journal of Endocrinology
In patients with diabetes mellitus (DM), impairments of circadian rhythms, including the sleep–wake cycle, blood pressure, and plasma melatonin concentrations, are frequently observed. Animal models of DM are also reported to show aberrant circadia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c1252e1ab48ab1d12e777c25e7fc46
Autor:
Takahiko Yano, Yusuke Adachi, Yuji Shimizu, Masaharu Nakayama, Taiji Asami, Katsuya Sakimura, Yasuko Terao
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(11)
Oxytocin (OT) is a neuropeptide involved in a wide variety of physiological actions, both peripherally and centrally. Many human studies have revealed the potential of OT to treat autism spectrum disorders and schizophrenia. OT interacts with the OT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c5cecdcae546073b098d7e86007695
https://pubmed.ncbi.nlm.nih.gov/28438540
https://pubmed.ncbi.nlm.nih.gov/28438540
Autor:
Maiko, Tanaka, Yoshiro, Tomimatsu, Katsuya, Sakimura, Yoshikazu, Ootani, Yuu, Sako, Takuto, Kojima, Kazuyoshi, Aso, Takahiko, Yano, Keisuke, Hirai
Publikováno v:
Peptides. 95
The aim of this study was to investigate peripheral and central roles of corticotropin-releasing factor (CRF) in endocrinological and behavioral changes. Plasma adrenocorticotropin (ACTH) concentration was measured as an activity of hypothalamic-pitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c458f45c2a082376a6f8d6f1a8b2c0c6
https://pubmed.ncbi.nlm.nih.gov/28689880
https://pubmed.ncbi.nlm.nih.gov/28689880
Publikováno v:
Journal of neuroscience research. 94(10)
NMDA receptor dysfunctions are hypothesized to underlie the pathophysiology of schizophrenia, and treatment with D-serine (D-Ser), an NMDA receptor coagonist, may improve the clinical symptoms of schizophrenia. Thus, upregulating the synaptic D-Ser l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81e364cb04a0781eb00e2f55b8328625
https://pubmed.ncbi.nlm.nih.gov/27302861
https://pubmed.ncbi.nlm.nih.gov/27302861
Publikováno v:
Neuropharmacology. 55:1300-1306
We previously reported the involvement of cannabinoid CB1 receptors (CB1Rs) and nicotinic acetylcholine receptors (nAChRs) in the reinstatement of methamphetamine (MAP)-seeking behavior (lever-pressing response for MAP reinforcement under saline infu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7017159d17d4a60b3b502f50fbb8817d
https://doi.org/10.1016/j.neuropharm.2008.08.012
https://doi.org/10.1016/j.neuropharm.2008.08.012