Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Katsuya Harada"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 127, Iss 3, Pp 362-369 (2015)
Despite the human 5-HT5A receptor being cloned in 1994, the biological function of this receptor has not been extensively characterized due to a lack of specific ligands. We recently reported that the selective 5-HT5A receptor antagonist ASP5736 amel
Externí odkaz:
https://doaj.org/article/b01a7889f4fd426698797771c050b807
Autor:
Takuya Maemoto, Miho Tada, Takuma Mihara, Noriko Ueyama, Hideaki Matsuoka, Katsuya Harada, Takayuki Yamaji, Kiyoharu Shirakawa, Satoru Kuroda, Atsushi Akahane, Akinori Iwashita, Nobuya Matsuoka, Seitaro Mutoh
Publikováno v:
Journal of Pharmacological Sciences, Vol 96, Iss 1, Pp 42-52 (2004)
Adenosine A1 receptors in the brain are believed to play an important role in brain functioning. We have discovered a novel adenosine A1 receptor antagonist, FR194921 (2-(1-methyl-4-piperidinyl)-6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-3(2H)-pyridazin
Externí odkaz:
https://doaj.org/article/860f43174114496499f11078d16d5768
Autor:
Monica M. Marcus, Ai Moriyama, Masako Furutani, Mayako Yamazaki, Junko Yarimizu, Mayuko Okabe, Noriyuki Yamamoto, Katsuya Harada, Torgny H. Svensson
Publikováno v:
European Neuropsychopharmacology. 28:620-629
The 5-HT5A receptor is arguably the least understood 5-HT receptor. Despite widespread expression in human and rodent brains it lacks specific ligands. Our previous results suggest that 5-HT5A receptor antagonists may be effective against cognitive i
Autor:
Masako Furutani, Ai Moriyama, Torgny H. Svensson, Mayuko Okabe, Katsuya Harada, Noriyuki Yamamoto, Monica M. Marcus, Junko Yarimizu, Mayako Yamazaki
Publikováno v:
European Neuropsychopharmacology. 29:S414-S415
Autor:
Mayako, Yamazaki, Noriyuki, Yamamoto, Junko, Yarimizu, Mayuko, Okabe, Ai, Moriyama, Masako, Furutani, Monica M, Marcus, Torgny H, Svensson, Katsuya, Harada
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 28(5)
The 5-HT
Autor:
Katsuya Harada, Miwako Shobo, Hiroshi Yamada, Keni Ni, Takuma Mihara, Yuji Kondo, Yukihiko Kayama, Megumi Irie, Nobuya Matsuoka
Publikováno v:
Behavioural Brain Research. 216:561-568
Body weight gain is one of the most serious side effects associated with clinical use of antipsychotics. However, the mechanisms by which antipsychotics induce body weight gain are unknown, and no reliable animal models of antipsychotics-induced weig
Autor:
Katsuya Harada, Noriyuki Yamamoto, Miwako Shobo, Masaaki Katsuoka, Yuji Kondo, Nobuya Matsuoka, Takuma Mihara, Hiroshi Yamada, Keni Ni
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 333:772-781
The antipsychotic drug zotepine [ZTP; 2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethan-1-amine] is known to have not only atypical antipsychotic effects but also antidepressive effects in schizophrenia patients. Norzotepine [norZTP; N-des
Publikováno v:
Folia Pharmacologica Japonica. 136:128-132
統合失調症は,幻覚,妄想などの陽性症状,自閉,感情鈍麻などの陰性症状および認知機能障害を主要症状とする代表的な精神疾患である.統合失調症の発症機序としてドパミン神経系
Autor:
Kunio Kato, Nobumasa Kato, Katsuya Harada, A. Hoshino, T. Yamaji, N. Matsuoka, Shigeru Morinobu, Kazuhisa Kohda, J. Motohashi
Publikováno v:
Neuroscience. 148:22-33
Post-traumatic stress disorder (PTSD) is a stress-related mental disorder caused by traumatic experience, and presents with characteristic symptoms, such as intrusive memories, a state of hyperarousal, and avoidance, that endure for years. Single-pro
Autor:
Yasuharu Nishino, Masahito Nakata, Naoaki Mita, Ryou Yasuda, Katsuya Harada, Hidetoshi Amano, Teruo Kushida, Yukio Nozawa
Publikováno v:
Nuclear Technology. 151:341-345
A field emission-type scanning electron microscope (FE-SEM) for observation of irradiated fuels and materials was installed at the Reactor Fuel Examination Facility at the Japan Atomic Energy Resea...