Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Katsuya, Morita"'
Autor:
Ayako Jinzenji, Chiharu Sogawa, Takuya Miyawaki, Xue-fang Wen, Dan Yi, Kazumi Ohyama, Shigeo Kitayama, Norio Sogawa, Katsuya Morita
Publikováno v:
Journal of Pharmacological Sciences, Vol 125, Iss 2, Pp 217-226 (2014)
Abstract.: The GABAergic system in the spinal cord has been shown to participate in neuropathic pain in various animal models. GABA transporters (GATs) play a role in controlling the synaptic clearance of GABA; however, their role in neuropathic pain
Externí odkaz:
https://doaj.org/article/7a8ceb6c96eb48a485de19a2de948d9d
Autor:
Katsuya Morita, Minoru Saida, Norimitsu Morioka, Tomoya Kitayama, Yasumasa Akagawa, Toshihiro Dohi
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 3, Pp 492-504 (2008)
Although cyclic ADP-ribose (cADPR), a novel Ca2+-mobilizing mediator, is suggested to be involved in the functions of neutrophils in rodents, its role in human neutrophils remains unclear. The present study examined the ability of cADPR to mobilize C
Externí odkaz:
https://doaj.org/article/79f8f52cbf0d48fa9f3dd518049d6014
Autor:
Katsuya Morita, Seiji Shiraishi, Naoyo Motoyama, Tomoya Kitayama, Takashi Kanematsu, Yasuhito Uezono, Toshihiro Dohi
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91746 (2014)
Bone cancer pain is the most severe among cancer pain and is often resistant to current analgesics. Thus, the development of novel analgesics effective at treating bone cancer pain are desired. Platelet-activating factor (PAF) receptor antagonists we
Externí odkaz:
https://doaj.org/article/fc5716b84f98406c8afa26062897669e
Autor:
Chiharu Sogawa, Chieko Mitsuhata, Kei Kumagai-Morioka, Norio Sogawa, Kazumi Ohyama, Katsuya Morita, Katsuyuki Kozai, Toshihiro Dohi, Shigeo Kitayama
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e11945 (2010)
BACKGROUND: The transporters for dopamine (DAT) and norepinephrine (NET) are members of the Na+- and Cl--dependent neurotransmitter transporter family SLC6. There is a line of evidence that alternative splicing results in several isoforms of neurotra
Externí odkaz:
https://doaj.org/article/670a8e5b939e4fe5ac3434a7b83d12df
Publikováno v:
In Journal of Pharmacological Sciences 2006 101(1):40-51
Autor:
Kae Harada, Katsuya Morita, Tomoya Kitayama, Mitsugi Okada, Masato Hirata, Taiga Yoshinaka, Kana Oue, Masaki Hayashiuchi, Satoshi Asano, Youngnam Kang, Masahiro Irifune, Takashi Kanematsu, Yosuke Yamawaki
Publikováno v:
Journal of Anesthesia. 31:531-538
The aim of this study was to investigate the action of general anesthetics in phospholipase C-related catalytically inactive protein (PRIP)-knockout (KO) mice that alter GABAA receptor signaling. PRIP regulates the intracellular trafficking of β sub
Publikováno v:
Neurochemistry International. 101:120-131
We previously demonstrated, using a DNA microarray analysis, the down-regulated expression of the slc30a1 gene (zinc transporter 1, ZnT1) in a neuropathic pain model induced by partial sciatic nerve ligation (PSNL). Zinc is an essential trace mineral
Autor:
Shigeko Katoh, Nanao Kamada, Masahiro Okada, Yumiko Yamaguchi, Hidemi Sasaki, Kosuke Okada, Katsuya Morita, Masayuki Kakehashi
Publikováno v:
Geriatrics & Gerontology International. 17:262-269
AIM: In an attempt to decrease the incidence of falls and fall-related fractures at a special geriatric nursing home, we endeavored to reduce diuretic doses, and examined the relationship between the effectiveness of this approach with the body compo
Autor:
Tomoya Kitayama, Naoyo Motoyama, Fusanori Nishimura, Katsuya Morita, Yasuhito Uezono, Seiji Shiraishi, Takashi Kanematsu, Toshihiro Dohi
Publikováno v:
European Journal of Pain. 17:1156-1167
Background Platelet-activating factor (PAF) has been implicated in the pathology of neuropathic pain. Previous studies reported that PAF receptor (PAF-R) antagonists have varied anti-allodynia effects by route of administration and nerve injury model
Autor:
Keisuke Mgita, Katsuya Morita, Nami Kikushige, Shinya Ueno, Takashi Kanematsu, Rizia Sultana, Tomoya Kitayama, Masato Hirata
Publikováno v:
Molecular Pain
Background An inositol 1, 4, 5-trisphosphate binding protein, comprising 2 isoforms termed PRIP-1 and PRIP-2, was identified as a novel modulator for GABAA receptor trafficking. It has been reported that naive PRIP-1 knockout mice have hyperalgesic r