Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Katsutoshi Yokoi"'
Autor:
Etsuko Shibuya, Toshikatsu Kaburaki, Shunya Sakamoto, Katsutoshi Yokoi, Yuri Asukata, Yujiro Fujino, Hiroshi Goto, Nobuhisa Mizuki, Akira Meguro, Nobuyoshi Kitaichi, Shigeaki Ohno, Kenichi Namba
Publikováno v:
Ocular Immunology and Inflammation. 23:S1-S23
Diagnosis and treatment of Behçet's disease (BD) have continued to undergo new changes in recent years. We organized a Compilation Committee for Guidelines on Diagnosis and Treatment of Ocular Behçet's Disease with five ophthalmology research facil
Autor:
S. Iqball, Naoyasu Umeda, Shu Kachi, Katsutoshi Yokoi, Peter A. Campochiaro, Katie Binley, Daisuke Muramatu, O. Kan, Hideo Akiyama, Stuart Naylor
Publikováno v:
Human Gene Therapy. 20:31-39
Equine infectious anemia virus (EIAV) is a nonprimate lentivirus that does not cause human disease. Subretinal injection into mice of a recombinant EIAV lentiviral vector in which lacZ is driven by a CMV promoter (EIAV CMV LacZ) resulted in rapid and
Autor:
Jon Cao, Naoyasu Umeda, Shu Kachi, Katsutoshi Yokoi, Dellamary Luis A, Betty Tam, John Doukas, Adrienne Racanelli-Layton, Michael D. Martin, Hideo Akiyama, Zoe Chen, Sankaranarayana Pillai Mahesh, Peter A. Campochiaro, Glenn Noronha, Richard Soll, John Hood
Publikováno v:
Journal of Cellular Physiology. 216:29-37
Age-related macular degeneration, diabetic retinopathy, and retinal vein occlusions are complicated by neovascularization and macular edema. Multi-targeted kinase inhibitors that inhibit select growth factor receptor tyrosine kinases and/or component
Publikováno v:
Ocular Immunology and Inflammation. 11:269-275
To characterize the clinical features of ocular toxocariasis and to describe the unique aspects of the disease in Japan.Thirty-six cases diagnosed as ocular toxocariasis at the uveitis clinic of Tokyo Medical University Hospital were analyzed retrosp
Publikováno v:
Japanese journal of ophthalmology. 54(5)
To characterize retinal macroaneurysm, which although rare, has been reported as a specific complication of ocular sarcoidosis. Ninety-seven sarcoidosis patients with intraocular inflammation diagnosed at the Uveitis Clinic of Tokyo Medical Universit
Autor:
Tsunehiko Yoshida, Katsutoshi Yokoi, Peter A. Campochiaro, Aling Dong, Jikui Shen, Bing Xie, Sean F. Hackett
Publikováno v:
Journal of cellular physiology. 219(3)
Mice deficient in superoxide dismutase 1 (Sod1(-/-) mice) develop many features seen in patients with age-related macular degeneration (AMD) including choroidal neovascularization (NV). We sought to determine if the absence of SOD1 contributes to the
Autor:
Ved P. Pathak, Chun P. Chow, Shiyin Yee, Michael D. Martin, Binqi Zeng, Hong Zhu, Shu Kachi, John Doukas, Naoyasu Umeda, Andrew McPherson, Dellamary Luis A, Hideo Akiyama, J. Hood, Boris Klebansky, Moorthy S.S. Palanki, Richard M. Fine, Katsutoshi Yokoi, Peter A. Campochiaro, Ahmed A Kousba, Joel Renick, Glenn Noronha, Dan Lohse, Xinshan Kang, Richard M. Soll, Colleen Gritzen, Chi Ching Mak, Steven Hu, Jianguo Cao
Publikováno v:
Journal of medicinal chemistry. 51(6)
Age-related macular degeneration (AMD) is one of the leading causes of loss of vision in the industrialized world. Attenuating the VEGF signal in the eye to treat AMD has been validated clinically. A large body of evidence suggests that inhibitors ta
Autor:
Richard T. Surosky, Katsutoshi Yokoi, Dmitry Guschin, Philip D. Gregory, Shu Kachi, Liza M Africa, Huanda Steve Zhang, Qi Yu, Sharon Kaye Spratt, Robin R. Ali, James W B Bainbridge, Kamaljit S. Balaggan, Peter A. Campochiaro, Mike Kunis
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 15(11)
Zinc finger protein transcription factors (ZFP TFs) have been shown to positively or negatively regulate the expression of endogenous genes involved in a number of different disease processes. In this study we investigated whether gene transfer of an
Autor:
Philip D. Gregory, S. Kaye Spratt, Shu Kachi, Peter A. Campochiaro, Katsutoshi Yokoi, H. Steve Zhang, R. Jude Samulski
Publikováno v:
Investigative ophthalmologyvisual science. 48(7)
Purpose Self-complementary AAV (scAAV) vectors have been developed to circumvent rate-limiting second-strand synthesis in single-stranded AAV vector genomes and to facilitate robust transgene expression at a minimal dose. In this study, the authors i
Autor:
Katsuji Kiuchi, Shu Kachi, Wei Hong Xiao, Raquel Lima e Silva, Sean F. Hackett, Naw Htee Khu, Maria C. Hatara, Catherine Thut, Jikui Shen, Peter A. Campochiaro, Hideo Akiyama, Thomas Lauer, Yuan Yuan Gong, Sadia Aslam, Katsutoshi Yokoi
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 21(12)
Hypoxia causes increased expression of several proteins that have the potential to promote neovascularization. Vascular endothelial growth factor (VEGF) is up-regulated by hypoxia in the retina and plays a central role in the development of several t