Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Katsura Hata"'
Autor:
Darline Dize, Mariscal Brice Tchatat Tali, Cyrille Armel Njanpa Ngansop, Rodrigue Keumoe, Eugenie Aimée Madiesse Kemgne, Lauve Rachel Tchokouaha Yamthe, Patrick Valere Tsouh Fokou, Boniface Pone Kamdem, Katsura Hata, Fabrice Fekam Boyom
Publikováno v:
Future Pharmacology, Vol 4, Iss 1, Pp 188-198 (2024)
Malaria, leishmaniasis, and African trypanosomiasis are protozoan diseases that constitute major global health problems, especially in developing countries; however, the development of drug resistance coupled with the toxicity of current treatments h
Externí odkaz:
https://doaj.org/article/0bdcdad3f31f4ef38faab4a008125d0e
A Strategic Partnership for Medicine Creation and Access to Medicine for Neglected Tropical Diseases
Autor:
Katsura, Hata
Publikováno v:
YAKUGAKU ZASSHI. 142:703-708
Neglected tropical diseases (NTDs) are communicable diseases that are uncommon in developed countries but epidemic in developing countries of the tropical and subtropical regions around the world. One of the important contributions expected of pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368c2f1f7d92452f5e737fe07c333b77
https://doi.org/10.1248/yakushi.21-00210-4
https://doi.org/10.1248/yakushi.21-00210-4
Autor:
Katsura Hata
Publikováno v:
Parasitology international. 81
Neglected tropical diseases (NTDs) are communicable diseases that are uncommon in developed countries but epidemic in developing countries in tropical and subtropical regions of the world. One of the important contributions expected of pharmaceutical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34175a659ea89fdd26305a2cd3e60483
https://pubmed.ncbi.nlm.nih.gov/33370607
https://pubmed.ncbi.nlm.nih.gov/33370607
Autor:
Jayme Fernandes, Igor Estevao, Joaquim Gascon, Isabela Ribeiro, Erika Correia, Rudy Parrado, Graeme Bilbe, Faustino Torrico, Gimena Rojas, Lourdes Ortiz, Daniel Lozano, Wilson Garcia, Uriel Ortega-Rodriguez, Alejandro Palacios, Roger Arteaga, Michel Vaillant, Katsura Hata, Lineth Garcia, Edgar Schuck, Fabiana Barreira, Cristina Alonso-Vega, Makoto Asada, Jimmy Pinto, Juan Carlos Ramirez, Tayná Barboza, Nathalie Strub-Wourgaft, María-Jesús Pinazo, Anabelle de la Barra, Bethania Blum, Maria Tays Mendes, Sergio Sosa-Estani, Alejandro G. Schijman, Igor C. Almeida, Ivana Martinez, Noritsugu Maki, Jhonny Camacho Borja
Publikováno v:
The Lancet. Infectious diseases. 21(8)
Current treatment for Chagas disease with the only available drugs, benznidazole or nifurtimox, has substantial limitations, including long treatment duration and safety and tolerability concerns. We aimed to evaluate the efficacy and safety of new b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6105a98e4de2ebe2b2c1177ce5d150
https://pubmed.ncbi.nlm.nih.gov/34331889
https://pubmed.ncbi.nlm.nih.gov/34331889
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:960-971
Continued research toward the development of new antifungals that act via inhibition of glycosylphosphatidylinositol (GPI) biosynthesis led to the design of E1210. In this study, we assessed the selectivity of the inhibitory activity of E1210 against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c117b9fd092aa3242e82179a19100b74
https://doi.org/10.1128/aac.00731-11
https://doi.org/10.1128/aac.00731-11
Autor:
Norio Murai, Naoaki Watanabe, Kentaro Yoshimatsu, Kazutaka Nakamoto, Satoshi Inoue, Katsura Hata, Miyuki Okubo, Jiro Sonoda, Syuji Shirotori, Shinya Abe, Makoto Asada, Takaaki Horii, Mamiko Miyazaki, Masayuki Matsukura, Keigo Tanaka
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:4543-4551
E1210 is a first-in-class, broad-spectrum antifungal with a novel mechanism of action—inhibition of fungal glycosylphosphatidylinositol biosynthesis. In this study, the efficacies of E1210 and reference antifungals were evaluated in murine models o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257f83af702974ea221537565b73ae97
https://doi.org/10.1128/aac.00366-11
https://doi.org/10.1128/aac.00366-11
Autor:
Katsura Hata
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :SY45-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd1d8cd427bc868e32f1e60442a9a0b5
https://doi.org/10.1254/jpssuppl.wcp2018.0_sy45-1
https://doi.org/10.1254/jpssuppl.wcp2018.0_sy45-1
Autor:
Kentaro Yoshimatsu, Yoshifumi Jigami, Junko Kai, Kazutaka Nakamoto, Junro Kuromitsu, Katsura Hata, Naoaki Watanabe, Mamiko Tsuchiya, Takeshi Nagasu, Koji Sagane, Fuminori Ohba, Kappei Tsukahara
Publikováno v:
Molecular Microbiology. 48:1029-1042
Glycosylphosphatidylinositol (GPI)-anchored cell wall mannoproteins are required for the adhesion of pathogenic fungi, such as Candida albicans, to human epithelium. Small molecular inhibitors of the cell surface presentation of GPI-anchored mannopro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e93d7cb1d94e0bf41f18bd69dfe5bff
https://doi.org/10.1046/j.1365-2958.2003.03481.x
https://doi.org/10.1046/j.1365-2958.2003.03481.x
Autor:
Shinya Abe, Masayuki Matsukura, Satoshi Inoue, Makoto Asada, Naoaki Watanabe, Katsura Hata, Takaaki Horii, Keigo Tanaka, Kazutaka Nakamoto, Mamiko Miyazaki, Norio Murai, Syuji Shirotori
Publikováno v:
Chemistry Letters. 39:1033-1035
We described a rare example of an effective isoxazole synthesis via a 1,3-dipolar cycloaddition using ZnCl2, which allowed us to synthesize novel (2-aminopyridin-3-yl)isoxazole derivatives effectiv...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dd117f8339b7778f42ffa322a015d2e
https://doi.org/10.1246/cl.2010.1033
https://doi.org/10.1246/cl.2010.1033
Autor:
Kentaro Yoshimatsu, Masayuki Matsukura, Katsura Hata, Norio Murai, Naoaki Watanabe, Makoto Asada, Keigo Tanaka, Kazutaka Nakamoto, Shinya Abe, Satoshi Inoue, Itaru Tsukada, Toru Haneda, Mamiko Miyazaki, Norihiro Ueda
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:4624-4626
Quinoline amide, azaindole amide and pyridine amides were synthesized and tested for in vitro antifungal activity against fungi. These synthesized amides have potent antifungal activity against Candida albicans and Aspergillus fumigatus. Our results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4838bd0aa2a4b8c399d03d69b139286
https://doi.org/10.1016/j.bmcl.2010.06.005
https://doi.org/10.1016/j.bmcl.2010.06.005