Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Katsunori Shirane"'
Autor:
Katsunori Shirane, Atsushi Mizoguchi, Yasuyo Shimomura, Ken Sugimoto, Atsuhiro Ogawa, Kiyotaka Nagahama
Publikováno v:
Gastroenterology. 134:459-469
Background & Aims: Dysregulated host/microbial interactions induce the development of colitis by activating deleterious acquired immune responses. Activation of CD4 + T cells is mainly induced through signaling machinery associated with immunologic s
Autor:
Yasuyo Shimomura, Kiyotaka Nagahama, Atsushi Mizoguchi, Emiko Mizoguchi, Atsushiro Ogawa, Richard S. Blumberg, Ken Sugimoto, Atul K. Bhan, Takashi Nagaishi, Katsunori Shirane, Hidetoshi Takedatsu
Publikováno v:
Journal of Clinical Investigation. 117:605-615
Granulomas represent a localized inflammatory reaction that is characteristically observed in many inflammatory conditions. However, the mechanisms of granuloma formation have not been fully defined. Herein we demonstrate, by using experimental model
Autor:
Yukiha Ishikawa, Kaoru Segawa, Ryo Kuji, Yukito Kobayashi, Seiji Kubota, Katsunori Shirane, Takeshi Sato, Takayuki Murata, Shiori Furukawa, Chiemi Tareyanagi, Kiyoshi Furukawa
Publikováno v:
Glycobiology. 24(6)
Our previous studies showed that mouse β4-galactosyltransferase 5 (β4GalT5) is a lactosylceramide (Lac-Cer) synthase, and that its gene expression increases by 2- to 3-fold upon malignant transformation of cells. In the present study, we examined w
Publikováno v:
Glycobiology. 11:813-820
Several studies showed that Sf-9 cells can synthesize the galactosylated N-linked oligosaccharides if beta-1,4-galactosyltransferase (beta-1,4-GalT) is supplied. The full-length human beta-1,4-GalT I, II, III, IV, V, and VI cDNAs were independently t
Publikováno v:
Biochemical and Biophysical Research Communications. 265:434-438
In spite of marked changes in the glycosylation upon malignant transformation of cells, no biological significance of beta-1, 4-galactosyltransferase (beta-1,4-GalT) activities has been elucidated. When beta-1,4-GalT activities toward 1 mM GlcNAcbeta
Publikováno v:
Biochemical and biophysical research communications. 276(3)
Since our previous study showed that the gene expression level of beta-1,4-galactosyltransferase (beta-1,4-GalT) V is only increased in mouse NIH3T3 transformant and that beta-1,4-GalT V preferentially galactosylates the GlcNAcbeta1 --> 6Man branch o
Autor:
Yasushi Okamoto, Hiroyuki Yamazaki, Katsunori Shirane, Kiyoshi Fukuchi, Kiyoshi Furukawa, Masahiro Tsuji
Publikováno v:
Biochimica et biophysica acta. 1268(3)
N-3554S, an optically active S-isomer of α-dihydrodecaprenyl phosphate, reduced the tumorigenicity of cultured B16-F10 mouse melanoma cells probably by affecting protein N -glycosylation. Accordingly, membrane glycoprotein samples were prepared from
Publikováno v:
Atherosclerosis. 102:227-228
Endothelin-1 (ET-l) is a potent vasoconstrictor peptide with 2 1 -amino-acid-residue originally isolated from culture medium of porcine endothelial cells [ 11. Human ET-l is generated from big ET-l with 38-amino-acid-residue by an endothelin converti