Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Katsunori Sasaki"'
Autor:
Yuta Takeuchi, Yizheng Wang, Katsunori Sasaki, Osamu Sato, Takahiro Tsuchikawa, Linan Wang, Yasunori Amaishi, Sachiko Okamoto, Junichi Mineno, Yoshifumi Hirokawa, Kanako C. Hatanaka, Yutaka Hatanaka, Takuma Kato, Hiroshi Shiku, Satoshi Hirano
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 116052- (2024)
Chimeric antigen receptor T-cell (CAR-T) therapy has demonstrated impressive success in the treatment of patients with hematologic tumors yet achieved very limited efficacy for solid tumors due to hurdles unique to solid tumors. It is also noted that
Externí odkaz:
https://doaj.org/article/88465710c13d4cf39acdbf42b435c5e8
Autor:
Kengo Sasaki, Daisuke Sasaki, Katsunori Sasaki, Yuto Nishidono, Akihiro Yamamori, Ken Tanaka, Akihiko Kondo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Daikenchuto (DKT) is a Japanese traditional herbal (Kampo) medicine containing ginseng, processed ginger, and Japanese or Chinese pepper. We aimed to determine how DKT affects human colonic microbiota. An in vitro microbiota model was establ
Externí odkaz:
https://doaj.org/article/e26380f2dca04cc094b9a7b231294925
Autor:
Mitsunobu Oba, Yoshitsugu Nakanishi, Tomoko Mitsuhashi, Katsunori Sasaki, Kanako C. Hatanaka, Masako Sasaki, Ayae Nange, Asami Okumura, Mariko Hayashi, Yusuke Yoshida, Takeo Nitta, Takashi Ueno, Toru Yamada, Masato Ono, Shota Kuwabara, Keisuke Okamura, Takahiro Tsuchikawa, Toru Nakamura, Takehiro Noji, Toshimichi Asano, Kimitaka Tanaka, Kiyoshi Takayama, Yutaka Hatanaka, Satoshi Hirano
Publikováno v:
Cancers, Vol 15, Iss 6, p 1878 (2023)
The epithelial–mesenchymal transition (EMT) contributes to the metastatic cascade in various tumors. C-C chemokine receptor 7 (CCR7) interacts with its ligand, chemokine (C-C motif) ligand 19 (CCL19), to promote EMT. However, the association betwee
Externí odkaz:
https://doaj.org/article/27c5b411d76a42038eacf2928c534354
Autor:
Osamu Sato, Takahiro Tsuchikawa, Takuma Kato, Yasunori Amaishi, Sachiko Okamoto, Junichi Mineno, Yuta Takeuchi, Katsunori Sasaki, Toru Nakamura, Kazufumi Umemoto, Tomohiro Suzuki, Linan Wang, Yizheng Wang, Kanako C. Hatanaka, Tomoko Mitsuhashi, Yutaka Hatanaka, Hiroshi Shiku, Satoshi Hirano
Publikováno v:
Cancers, Vol 15, Iss 3, p 601 (2023)
Chimeric antigen receptor engineered T cell (CAR-T) therapy has high therapeutic efficacy against blood cancers, but it has not shown satisfactory results in solid tumors. Therefore, we examined the therapeutic effect of CAR-T therapy targeting carci
Externí odkaz:
https://doaj.org/article/e6979d59a4204000be80c906f54b0464
Autor:
Hiroki Kushiya, Kei Hiraoka, Tomohiro Suzuki, Kazuho Inoko, Akihito Inagaki, Hiroki Niwa, Katsunori Sasaki, Toru Nakamura, Takahiro Tsuchikawa, Toshiaki Shichinohe, Douglas J. Jolly, Noriyuki Kasahara, Satoshi Hirano
Publikováno v:
Cancers, Vol 14, Iss 23, p 5820 (2022)
Therapeutic efficacy of retroviral replicating vector (RRV)-mediated prodrug activator gene therapy has been demonstrated in a variety of tumor models, but clinical investigation of this approach has so far been restricted to glioma and gastrointesti
Externí odkaz:
https://doaj.org/article/4144a73fb2e4439788ff1754fbd50090
Autor:
Daihachiro Tomotsune, Kanji Hirashima, Masako Fujii, Fengming Yue, Ken Matsumoto, Sakiko Takizawa-Shirasawa, Tadayuki Yokoyama, Katsunori Sasaki
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162693 (2016)
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) are potential resources for the regeneration of defective organs, including the liver. However, some obstacles must be overcome before this becomes reality. Undifferentiated cells
Externí odkaz:
https://doaj.org/article/9fe789ed5d3c4a1d85e7ce89d3ea7d71
Autor:
Katsunori Sasaki, Hinako Ichikawa, Shunsuke Takei, Hee Sung No, Daihachiro Tomotsune, Yoshiya Kano, Tadayuki Yokoyama, Sakiko Sirasawa, Akimi Mogi, Susumu Yoshie, Shujiro Sasaki, Satoshi Yamada, Ken Matsumoto, Masahiro Mizuguchi, Fengming Yue, Yoshiki Tanaka
Publikováno v:
The Scientific World Journal, Vol 9, Pp 884-890 (2009)
To induce hepatocytes from human embryonic stem (hES) cells easily and effectively, a simple suspension culture method that separates ES colonies with a scraper and transfers them into newly developed, nonadherent MPC (2-methacryloyloxyethyl phosphor
Externí odkaz:
https://doaj.org/article/b7a6da6b14614c26ac697d43060af61b
Autor:
Ikkei Takashimizu, Yoshiki Tanaka, Susumu Yoshie, Yoshiya Kano, Hinako Ichikawa, Li Cui, Naoko Ogiwara, Kohei Johkura, Katsunori Sasaki
Publikováno v:
The Scientific World Journal, Vol 9, Pp 190-199 (2009)
The objective of this study was to establish Liv2, a surface marker of mouse immature hepatocytes (hepatoblasts), as a selection tool for embryonic stem (ES) cell–derived immature hepatocytes by acquiring basic data on Liv2 in normal mouse embryos
Externí odkaz:
https://doaj.org/article/ea8e7fdbde3748709b45a825c4db111b
Autor:
Kazumasa Nakamura, Junpei Sasajima, Yusuke Mizukami, Yoshiaki Sugiyama, Madoka Yamazaki, Rie Fujii, Toru Kawamoto, Kazuya Koizumi, Kazuya Sato, Mikihiro Fujiya, Katsunori Sasaki, Satoshi Tanno, Toshikatsu Okumura, Norihiko Shimizu, Jun-ichi Kawabe, Hidenori Karasaki, Toru Kono, Masaaki Ii, Nabeel Bardeesy, Daniel C Chung, Yutaka Kohgo
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8824 (2010)
The hedgehog (Hh) pathway has been implicated in the pathogenesis of cancer including pancreatic ductal adenocarcinoma (PDAC). Recent studies have suggested that the oncogenic function of Hh in PDAC involves signaling in the stromal cells rather than
Externí odkaz:
https://doaj.org/article/4a2414c8d3ae4660a90536fd62dd8b3e
Autor:
Shunsuke Takei, Makoto Yamamoto, Li Cui, Fengming Yue, Kohei Johkura, Naoko Ogiwara, Hisae Iinuma, Kota Okinaga, Katsunori Sasaki
Publikováno v:
Cell Transplantation, Vol 14 (2005)
Because cardiomyocytes lose the ability to divide upon differentiation, myocardial failure is assumed to be generally irreversible. For terminal cardiac insufficiency, the potential for regenerative treatment by stem cells, especially embryonic stem
Externí odkaz:
https://doaj.org/article/d4fc569ca98b428d8f95df88fc2d67c2