Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Katsunori Kobayashi"'
Autor:
Keisuke Otsubo, Naoko Sakashita, Yuki Nishimoto, Yo Sato, Takehisa Tsutsui, Katsunori Kobayashi, Kanzo Suzuki, Eri Segi-Nishida
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Desmoplakin (Dsp) is a component of desmosomal cell–cell junctions that interacts with the cadherin complex and cytoskeletal intermediate filaments. In addition to its function as an adhesion component, Dsp is involved in various biological process
Externí odkaz:
https://doaj.org/article/07bd43a4187c443fbaa5b98173376a26
Autor:
Kei-ichi Katayama, Naoko Morimura, Katsunori Kobayashi, Danielle Corbett, Takehito Okamoto, Veravej G. Ornthanalai, Hayato Matsunaga, Wakako Fujita, Yoshifumi Matsumoto, Takumi Akagi, Tsutomu Hashikawa, Kazuyuki Yamada, Niall P. Murphy, Soichi Nagao, Jun Aruga
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104604- (2022)
Summary: SLITRK2 encodes a transmembrane protein that modulates neurite outgrowth and synaptic activities and is implicated in bipolar disorder. Here, we addressed its physiological roles in mice. In the brain, the Slitrk2 protein was strongly detect
Externí odkaz:
https://doaj.org/article/4c551bbb671f4e9d99a3161fe1d0f72d
Publikováno v:
Molecular Therapy: Oncolytics, Vol 19, Iss , Pp 294-307 (2020)
For cutaneous squamous cell carcinoma (cSCC), topical treatment is an essential option for patients who are not candidates for, or who refuse, surgery. Epidermal growth factor receptor (EGFR) plays a key role in the development of cSCC, but EGFR tyro
Externí odkaz:
https://doaj.org/article/7fe27f8daceb40538d6a9fd561077a75
Autor:
Masahiro Kishikawa, Jun Inoue, Hidetoshi Hamamoto, Katsunori Kobayashi, Takahiro Asakage, Johji Inazawa
Publikováno v:
Biochemistry and Biophysics Reports, Vol 26, Iss , Pp 101009- (2021)
Anaplastic thyroid cancer (ATC) is one of the most lethal types of human tumors. Lenvatinib can improve the disease control and prognosis in patients with ATC. However, there is an unmet need to develop a therapeutically safer and non-invasive strate
Externí odkaz:
https://doaj.org/article/99c42b063efc48c8b701f212359f48fc
Autor:
Katsunori Kobayashi, Hidenori Suzuki
Publikováno v:
Neuropsychopharmacology Reports, Vol 38, Iss 4, Pp 197-203 (2018)
Abstract Aim The identification of 7,8‐dihydroxyflavone (DHF) as a small molecule agonist for tropomyosin‐related kinase B (TrkB) facilitated understanding of the role of TrkB signaling in regulating higher brain functions. DHF can penetrate the
Externí odkaz:
https://doaj.org/article/9649d18470ba4307be44336666cc3dde
Autor:
Katsunori Kobayashi, Yasunori Mikahara, Yuka Murata, Daiki Morita, Sumire Matsuura, Eri Segi-Nishida, Hidenori Suzuki
Publikováno v:
iScience, Vol 23, Iss 4, Pp - (2020)
Summary: The hippocampal mossy fiber (MF) synapse has been implicated in the pathophysiology and treatment of psychiatric disorders. Alterations of dopaminergic and serotonergic modulations at this synapse are candidate mechanisms underlying antidepr
Externí odkaz:
https://doaj.org/article/19ca920428774f1e981c2f29d80138ae
Publikováno v:
Molecular Brain, Vol 11, Iss 1, Pp 1-4 (2018)
Abstract The dentate gyrus of the hippocampus has been implicated in the pathophysiological basis of neuropsychiatric disorders including schizophrenia. We have identified several mouse models of neuropsychiatric disorders with robust molecular and f
Externí odkaz:
https://doaj.org/article/3f4f459e873547e9af8e92a8a9f1b142
Autor:
Katsunori Kobayashi, Yumiko Ikeda, Minoru Asada, Hirofumi Inagaki, Tomoyuki Kawada, Hidenori Suzuki
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63662 (2013)
The hippocampal dentate gyrus has been implicated in a neuronal basis of antidepressant action. We have recently shown a distinct form of neuronal plasticity induced by the serotonergic antidepressant fluoxetine, that is, a reversal of maturation of
Externí odkaz:
https://doaj.org/article/6aca2915e1f84b9d90ce0e5275fe4727
Autor:
Katsunori Kobayashi, Satomi Umeda-Yano, Hidenaga Yamamori, Masatoshi Takeda, Hidenori Suzuki, Ryota Hashimoto
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18113 (2011)
Dysbindin-1 (dystrobrevin-binding protein 1, DTNBP1) is one of the promising schizophrenia susceptibility genes. Dysbindin protein is abundantly expressed in synaptic regions of the hippocampus, including the terminal field of the mossy fibers, and t
Externí odkaz:
https://doaj.org/article/223fe020aa504b1d81109d9063c5da63
Autor:
Katsunori, Kobayashi, Kisako, Shikano, Mahomi, Kuroiwa, Mio, Horikawa, Wakana, Ito, Akinori, Nishi, Eri, Segi-Nishida, Hidenori, Suzuki
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(33)
Dopamine D