Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Katsumi Uohama"'
Autor:
Katsumi Uohama, Yoshio Esumi, Masanori Hatsuoka, Hideaki Seki, Masayoshi Tanaka, Shin-ichi Ninomiya, Satoru Kimura
Publikováno v:
Drug Metabolism and Pharmacokinetics. 11:160-177
The absorption, distribution, metabolism and excretion of Ritipenem acoxil (RIPM-AC), an oral prodrug of antibiotic Ritipenem (RIPM), were investigated in rats and dogs after a single oral administration of 14C-RIPM-AC. 1. A fter oral administration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::038191c6436b56b7347d03fbfb8a0179
https://doi.org/10.2133/dmpk.11.160
https://doi.org/10.2133/dmpk.11.160
Autor:
Katsumi Uohama, Hideaki Seki, Masanori Hatsuoka, Masayoshi Tanaka, Satoru Kimura, Shin-ichi Ninomiya, Yoshio Esumi
Publikováno v:
Drug Metabolism and Pharmacokinetics. 11:188-193
1. Placental transfer of Ritipenem acoxil (RIPM-AC), an oral prodrug of antibiotic Ritipenem (RIPM), was investigated in rats on the 12th and 18th days of gestation after oral administration of 14C-RIPM-AC. Minor quantity of radioactivity was transfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e9a115aa4b8b886c133eb80dde32e19
https://doi.org/10.2133/dmpk.11.188
https://doi.org/10.2133/dmpk.11.188
Autor:
Hideaki Seki, Satoru Kimura, Shin-ichi Ninomiya, Masanori Hatsuoka, Shinobu Gunji, Yoshio Esumi, Masayoshi Tanaka, Katsumi Uohama
Publikováno v:
Drug Metabolism and Pharmacokinetics. 11:178-187
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de19effb6a52d5e569bc81b3344e3884
https://doi.org/10.2133/dmpk.11.178
https://doi.org/10.2133/dmpk.11.178
Autor:
Tetsuya Oida, Terumichi Nakagawa, Katsumi Uohama, Hideki Aishita, Yoshio Karasawa, Masafumi Sawada, Yoshihiro Kuroda, Yajimu Miyake, Toshihiko Fujii, Nobuyuki Hamanaka, Hisashi Miyazaki, Yoshio Esumi, Yutaka Sekine, Toshikazu Yamaguchi, Teruo Hatoyama
Publikováno v:
Drug Metabolism and Pharmacokinetics. 9:750-761
Metabolism of ataprost [5(E)-15-cyclopentyl-6, 9-deoxa-6, 9α-methylene 16, 17, 18, 19, 20-pentanor-PGI2, OP-41483], a prostacyclin derivative, was investigated in rats. After intravenous administration of [3H]ataprost, its metabolites in urine, bile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9057b31647b0e34d7098942eb217c02
https://doi.org/10.2133/dmpk.9.750
https://doi.org/10.2133/dmpk.9.750
Autor:
Yoshiharu Katami, Masashi Hirayama, Katsumi Uohama, Yoshinari Hasegawa, Yoshitaka Jin, Tatsuo Manabe, Yoshio Esumi
Publikováno v:
Drug Metabolism and Pharmacokinetics. 9:762-792
The placental transfer, excretion into milk and site of absorption of 14C RU44570 were investigated in normal rats and male rats with ligated loops of gas trointestinal tract. The absorption, distribution, metabolism and excretion of 14C-RU44570 were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e97aff37dee534aec6488a78f9b33be
https://doi.org/10.2133/dmpk.9.762
https://doi.org/10.2133/dmpk.9.762
Autor:
Minoru NAKAOKA, Hideo HAKUSUI, Yoshitaka JIN, Syuichirou TUTUMI, Akiko HIRONAKA, Hiromi HIRANO, Tomoyuki NOGUCHI, Katsumi UOHAMA, Michika TAKASAKI, Namiko SEKI, Yoshio ESUMI
Publikováno v:
Drug Metabolism and Pharmacokinetics. 9:247-257
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc45e76fea512cadce70bcfa5e638e0f
https://doi.org/10.2133/dmpk.9.247
https://doi.org/10.2133/dmpk.9.247
Autor:
Shigemi Kimura, Shin-ichi Ninomiya, James W Barnett, Katsumi Uohama, Takafumi Ichikawa, Yukio Yanagimoto, Jun Hiraki, Hideaki Seki, Hiroshi Seki
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 37(2)
Epsilon-polylysine is a homopolymer of L-lysine, containing approximately 30 L-lysine subunits, as synthesized in aerobic bacterial fermentation by Streptomyces albulus. epsilon -Polylysine is approved for food use in Japan as an antimicrobial preser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afacc394bf7669131b7e96b03b0a95b1
https://pubmed.ncbi.nlm.nih.gov/12726761
https://pubmed.ncbi.nlm.nih.gov/12726761
Autor:
Ken-ichiro Yoshida, George A. Sim, Katsumi Uohama, Akihiko Matsuo, Joseph D. Connolly, Shûichi Hayashi
Publikováno v:
Chemistry Letters. 14:935-938
The structures and conformations of 6β,12β-dihydroxy-3E,7E-dolabelladiene 6-p-bromobenzoate and acetoxyodontoschismenol 3S,4S-epoxide have been established By X-ray crystallographic analysis. The original assignment of the stereochemistry at C-12 o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a400ca3546937f8db864ed3d80672e50
https://doi.org/10.1246/cl.1985.935
https://doi.org/10.1246/cl.1985.935
Autor:
Akihiko Matsuo, Ken-ichiro Yoshida, Ki-ichiro Kamio, Joseph D. Connolly, George A. Sim, Katsumi Uohama
Publikováno v:
Phytochemistry. 27:1153-1159
Five new dolabellane diterpenoids have been isolated from the liverwort Odontoschisma denudatum, and their structures and absolute configurations have been determined on the basis of 1H and 13C NMR evidence and chemical correlation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::179e0e8e19530c2351ed3fedc66dfe3b
https://doi.org/10.1016/0031-9422(88)80293-0
https://doi.org/10.1016/0031-9422(88)80293-0
(+)-ACETOXYODONTOSCHISMENOL, A NEW DOLABELLANE DITERPENOID FROM THE LIVERWORTODONTOSCHISMA DENUDATUM
Publikováno v:
Chemistry Letters. 13:599-602
A new dolabellane diterpenoid, (+)-acetoxyodontoschismenol, displaying antifungal properties, has been isolated from the liverwort Odontoschisma denudatum, and its structure, including the absolute configuration, has been determined as (1R,6R,11R,12S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32fe20d86d52d2779057152a1b354b1c
https://doi.org/10.1246/cl.1984.599
https://doi.org/10.1246/cl.1984.599